Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Kidney Diseases D007674 29 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Lactose Intolerance D007787 2 associated lipids
Leukemia D007938 74 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Liver Diseases D008107 31 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lymphopenia D008231 2 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Melanosis D008548 4 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Ma C et al. NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis. 2016 Nature pmid:26934227
Padayachee T et al. The Detection of Metabolite-Mediated Gene Module Co-Expression Using Multivariate Linear Models. 2016 PLoS ONE pmid:26918614
Troche JR et al. Alcohol Consumption-Related Metabolites in Relation to Colorectal Cancer and Adenoma: Two Case-Control Studies Using Serum Biomarkers. 2016 PLoS ONE pmid:26967509
Medema S et al. Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. 2016 Schizophr Bull pmid:26385764
Arnold WR et al. Asymmetric Binding and Metabolism of Polyunsaturated Fatty Acids (PUFAs) by CYP2J2 Epoxygenase. 2016 Biochemistry pmid:27992998
Conte R et al. Pressurized liquid extraction and chemical characterization of safflower oil: A comparison between methods. 2016 Food Chem pmid:27451200
Montaño A et al. Fatty Acid and Phenolic Compound Concentrations in Eight Different Monovarietal Virgin Olive Oils from Extremadura and the Relationship with Oxidative Stability. 2016 Int J Mol Sci pmid:27886101
Zhao Z et al. The Association of Fatty Acid Levels and Gleason Grade among Men Undergoing Radical Prostatectomy. 2016 PLoS ONE pmid:27880795
Takabe W et al. Esterification of 24S-OHC induces formation of atypical lipid droplet-like structures, leading to neuronal cell death. 2016 J. Lipid Res. pmid:27647838
Zhang YH et al. The Use of Gene Ontology Term and KEGG Pathway Enrichment for Analysis of Drug Half-Life. 2016 PLoS ONE pmid:27780226
Rodrigues HG et al. Oral Administration of Linoleic Acid Induces New Vessel Formation and Improves Skin Wound Healing in Diabetic Rats. 2016 PLoS ONE pmid:27764229
Kojima K et al. A simple method for isolation and construction of markerless cyanobacterial mutants defective in acyl-acyl carrier protein synthetase. 2016 Appl. Microbiol. Biotechnol. pmid:27704180
Ishida K and Jolly ER Hsp70 May Be a Molecular Regulator of Schistosome Host Invasion. 2016 PLoS Negl Trop Dis pmid:27611863
Matthaus B et al. Some rape/canola seed oils: fatty acid composition and tocopherols. 2016 Z. Naturforsch., C, J. Biosci. pmid:27023318
Tel-Çayan G et al. A new fatty acid ester from an edible mushroom Rhizopogon luteolus. 2016 Nat. Prod. Res. pmid:26987031
Bothun GD et al. Cooperative effects of fatty acids and n-butanol on lipid membrane phase behavior. 2016 Colloids Surf B Biointerfaces pmid:26700234
Ramsden CE et al. Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids: Implications for idiopathic pain syndromes? 2016 Mol Pain pmid:27030719
Domenichiello AF et al. The effect of linoleic acid on the whole body synthesis rates of polyunsaturated fatty acids from α-linolenic acid and linoleic acid in free-living rats. 2016 J. Nutr. Biochem. pmid:27012633
Yary T et al. Serum n-6 polyunsaturated fatty acids, Δ5- and Δ6-desaturase activities, and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study. 2016 Am. J. Clin. Nutr. pmid:27009754
Abdullah BM et al. Polyesters Based on Linoleic Acid for Biolubricant Basestocks: Low-Temperature, Tribological and Rheological Properties. 2016 PLoS ONE pmid:27008312