Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Pneumonia, Viral D011024 3 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Pain D010146 64 associated lipids
Otitis Externa D010032 8 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Melanosis D008548 4 associated lipids
Malabsorption Syndromes D008286 16 associated lipids
Lymphopenia D008231 2 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Diseases D008107 31 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Ripoll-Rozada J et al. Type IV traffic ATPase TrwD as molecular target to inhibit bacterial conjugation. 2016 Mol. Microbiol. pmid:26915347
Ishida K and Jolly ER Hsp70 May Be a Molecular Regulator of Schistosome Host Invasion. 2016 PLoS Negl Trop Dis pmid:27611863
Venäläinen TM et al. Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. 2016 Am. J. Clin. Nutr. pmid:27581473
Bothun GD et al. Cooperative effects of fatty acids and n-butanol on lipid membrane phase behavior. 2016 Colloids Surf B Biointerfaces pmid:26700234
Alzate A et al. Preeclampsia prevention: a case-control study nested in a cohort. 2015 Colomb. Med. pmid:26848195
Lee CW et al. Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin. 2015 Biochem. Biophys. Res. Commun. pmid:26206084
Tucker RM et al. No Difference in Perceived Intensity of Linoleic Acid in the Oral Cavity between Obese and Nonobese Individuals. 2015 Chem. Senses pmid:26232811
Evans SJ et al. Plasma linoleic acid partially mediates the association of bipolar disorder on self-reported mental health scales. 2015 J Psychiatr Res pmid:26228402
Min JS et al. Monitoring the formation of cholesterol oxidation products in model systems using response surface methodology. 2015 Lipids Health Dis pmid:26201850
Farvid MS et al. Response to Letters Regarding Article, "Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies". 2015 Circulation pmid:26195494
Negrini R et al. pH-responsive lyotropic liquid crystals and their potential therapeutic role in cancer treatment. 2015 Chem. Commun. (Camb.) pmid:25783035
Fajardo VA et al. Cardiolipin linoleic acid content and mitochondrial cytochrome c oxidase activity are associated in rat skeletal muscle. 2015 Chem. Phys. Lipids pmid:25727371
Hashim RB et al. Fatty acid compositions of silver catfish, Pangasius sp. farmed in several rivers of Pahang, Malaysia. 2015 J Oleo Sci pmid:25748380
Chang TS et al. Palm oil derived trimethylolpropane triesters synthetic lubricants and usage in industrial metalworking fluid. 2015 J Oleo Sci pmid:25748374
Tyurina YY et al. LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. 2015 Free Radic. Res. pmid:25740198
Wang S et al. Plasma nutrient biomarkers are associated with waist-to-height ratio in youth with type 1 diabetes. 2015 J. Nutr. pmid:25733475
Nardi F et al. Proteasomal modulation of cellular SNAT2 (SLC38A2) abundance and function by unsaturated fatty acid availability. 2015 J. Biol. Chem. pmid:25653282
Fala AM et al. Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α. 2015 Sci Rep pmid:26237540
Beam J et al. Excess Linoleic Acid Increases Collagen I/III Ratio and "Stiffens" the Heart Muscle Following High Fat Diets. 2015 J. Biol. Chem. pmid:26240151
Okazaki H et al. Bongkrekic acid as a selective activator of the peroxisome proliferator-activated receptor γ (PPARγ) isoform. 2015 J Toxicol Sci pmid:25786526