Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Seizures D012640 87 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
pmid:
Cogo PE et al. Endogenous surfactant metabolism in critically ill infants measured with stable isotope labeled fatty acids. 1999 Pediatr. Res. pmid:10022597
Umezawa M et al. High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice. 1999 J. Nutr. pmid:10024623
Cunnane SC The long history of essential fatty acids but belated knowledge about linoleate deficiency per se: a paradox. 1999 J. Nutr. pmid:10024625
Aki T et al. Molecular cloning and functional characterization of rat delta-6 fatty acid desaturase. 1999 Biochem. Biophys. Res. Commun. pmid:10049752
Avery SV et al. Stimulation of strontium accumulation in linoleate-enriched Saccharomyces cerevisiae is a result of reduced Sr2+ efflux. 1999 Appl. Environ. Microbiol. pmid:10049882
Josyula S et al. Inhibition of DNA adduct formation of PhIP in female F344 rats by dietary conjugated linoleic acid. 1998 Nutr Cancer pmid:10050262
Josyula S and Schut HA Effects of dietary conjugated linoleic acid on DNA adduct formation of PhIP and IQ after bolus administration to female F344 rats. 1998 Nutr Cancer pmid:10050263
Jussila M et al. Separation of linoleic acid oxidation products by micellar electrokinetic capillary chromatography and nonaqueous capillary electrophoresis. 1999 Electrophoresis pmid:10065966
Rukkwamsuk T et al. Hepatic fatty acid composition in periparturient dairy cows with fatty liver induced by intake of a high energy diet in the dry period. 1999 J. Dairy Sci. pmid:10068949