Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Carcinoma, Hepatocellular D006528 140 associated lipids
Olfaction Disorders D000857 17 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Seizures D012640 87 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Ferry DR et al. A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. 2000 Ann. Oncol. pmid:11061613
French P et al. Fatty acid composition, including conjugated linoleic acid, of intramuscular fat from steers offered grazed grass, grass silage, or concentrate-based diets. 2000 J. Anim. Sci. pmid:11063308
Brynes AE et al. Diet-induced change in fatty acid composition of plasma triacylglycerols is not associated with change in glucagon-like peptide 1 or insulin sensitivity in people with type 2 diabetes. 2000 Am. J. Clin. Nutr. pmid:11063437
Granot E et al. Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. 2000 Am. J. Clin. Nutr. pmid:11063450
Cahoon EB et al. Formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid. 2001 J. Biol. Chem. pmid:11067856
Hochi S et al. Nuclear transfer in cattle : effect of linoleic acid-albumin on freezing sensitivity of enucleated oocytes. 2000 J. Vet. Med. Sci. pmid:11073086
Grechkin AN et al. The lipoxygenase pathway in tulip (Tulipa gesneriana): detection of the ketol route. 2000 Biochem. J. pmid:11085944
Lehtinen P and Laakso S Inhibition of linoleic acid oxidation by interaction with a protein-rich oat fraction. 2000 J. Agric. Food Chem. pmid:11087534
Louw L and Dannhauser A Keloids in rural black South Africans. Part 2: dietary fatty acid intake and total phospholipid fatty acid profile in the blood of keloid patients. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090250
Louw L Keloids in rural black South Africans. Part 3: a lipid model for the prevention and treatment of keloid formations. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090251