| MeSH term | MeSH ID | Detail |
|---|---|---|
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Hypertension, Renal | D006977 | 9 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Exocrine Pancreatic Insufficiency | D010188 | 6 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chatterjee MT et al. | Alterations in cellular lipids may be responsible for the transient nature of the yeast heat shock response. | 1997 | Microbiology (Reading, Engl.) | pmid:9308188 |
| Hayakawa F et al. | DNA cleavage reaction and linoleic acid peroxidation induced by tea catechins in the presence of cupric ion. | 1997 | Biochim. Biophys. Acta | pmid:9305782 |
| Moran JH et al. | Cytotoxicity of linoleic acid diols to renal proximal tubular cells. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9299596 |
| Rusnak A et al. | Cardiolipin remodeling in a Chinese hamster lung fibroblast cell line deficient in oxidative energy production. | 1997 | J. Bioenerg. Biomembr. | pmid:9298714 |
| de Waart FG et al. | Vitamin E supplementation in elderly lowers the oxidation rate of linoleic acid in LDL. | 1997 | Atherosclerosis | pmid:9298686 |
| Hall JA et al. | Lipid composition of hepatic and adipose tissues from normal cats and from cats with idiopathic hepatic lipidosis. | 1997 Jul-Aug | J. Vet. Intern. Med. | pmid:9298479 |
| López-Nicolás JM et al. | Kinetic characteristics of the enzymatic conversion in presence of cyclodextrins: study of the oxidation of polyunsaturated fatty acids by lipoxygenase. | 1997 | Biochim. Biophys. Acta | pmid:9295158 |
| Jensen CL et al. | Effect of dietary linoleic/alpha-linolenic acid ratio on growth and visual function of term infants. | 1997 | J. Pediatr. | pmid:9290604 |
| Carlson SE | Functional effects of increasing omega-3 fatty acid intake. | 1997 | J. Pediatr. | pmid:9290597 |
| Usha S and Balakrishnan A | c-myc, c-H-ras, and IP3 elevation in 18:2 n-6 dependent proliferation of lung cells. | 1997 Jul-Aug | In Vitro Cell. Dev. Biol. Anim. | pmid:9282304 |
| Batna A et al. | Lipid peroxidation in presence of ebselen. | 1997 | Chem. Phys. Lipids | pmid:9275309 |
| Fabritius D et al. | Biotransformation of linoleic acid with the Candida tropicalis M25 mutant. | 1997 | Appl. Microbiol. Biotechnol. | pmid:9274051 |
| Lopez Jimenez JA et al. | Linoleic acid metabolism in primary cultures of adult rat cardiomyocytes is impaired by aging. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9266846 |
| Jenkins TC | Ruminal fermentation and nutrient digestion in sheep fed hydroxyethylsoyamide. | 1997 | J. Anim. Sci. | pmid:9263076 |
| Feussner I et al. | Structural elucidation of oxygenated storage lipids in cucumber cotyledons. Implication of lipid body lipoxygenase in lipid mobilization during germination. | 1997 | J. Biol. Chem. | pmid:9261186 |
| Badart-Smook A et al. | Fetal growth is associated positively with maternal intake of riboflavin and negatively with maternal intake of linoleic acid. | 1997 | J Am Diet Assoc | pmid:9259708 |
| Bakker N et al. | Adipose fatty acids and cancers of the breast, prostate and colon: an ecological study. EURAMIC Study Group. | 1997 | Int. J. Cancer | pmid:9259395 |
| Risé P et al. | Effects of simvastatin on the metabolism of polyunsaturated fatty acids and on glycerolipid, cholesterol, and de novo lipid synthesis in THP-1 cells. | 1997 | J. Lipid Res. | pmid:9254057 |
| Castelli F et al. | Dipalmitoylphosphatidylcholine/linoleic acid mixed unilamellar vesicles as model membranes for studies on novel free-radical scavengers. | 1997 | J Pharmacol Toxicol Methods | pmid:9253749 |
| Siguel E | Essential fatty acid status in patients. | 1997 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:9252955 |
| Howlett NG and Avery SV | Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation. | 1997 | Appl. Environ. Microbiol. | pmid:9251184 |
| Parmentier HK et al. | Dietary unsaturated fatty acids affect antibody responses and growth of chickens divergently selected for humoral responses to sheep red blood cells. | 1997 | Poult. Sci. | pmid:9251147 |
| Bosca F et al. | Photophysical and photochemical characterization of a photosensitizing drug: a combined steady state photolysis and laser flash photolysis study on carprofen. | 1997 | Chem. Res. Toxicol. | pmid:9250417 |
| Thomson AB et al. | Nutrient uptake into undifferentiated and differentiated HT-29 cells in culture. | 1997 | Can. J. Physiol. Pharmacol. | pmid:9250367 |
| Hannah JS et al. | High fat, high cholesterol diets alter low density lipoprotein size and binding affinity in monkeys. | 1997 | Atherosclerosis | pmid:9247355 |
| Lanson M et al. | Supplementation of MCF-7 cells with essential fatty acids induces the activation of protein kinase C in response to IGF-1. | 1997 | J Lipid Mediat Cell Signal | pmid:9246607 |
| Haraguchi H et al. | Antioxidative action of diterpenoids from Podocarpus nagi. | 1997 | Planta Med. | pmid:9225601 |
| Shi F et al. | Permeability and metabolic properties of a trophoblast cell line (HRP-1) derived from normal rat placenta. | 1997 | Exp. Cell Res. | pmid:9223380 |
| Quoc KP and Dubacq JP | Effect of growth temperature on the biosynthesis of eukaryotic lipid molecular species by the cyanobacterium Spirulina platensis. | 1997 | Biochim. Biophys. Acta | pmid:9219908 |
| Jira W et al. | Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. | 1997 | Chem. Phys. Lipids | pmid:9219348 |
| Durgam VR and Fernandes G | The growth inhibitory effect of conjugated linoleic acid on MCF-7 cells is related to estrogen response system. | 1997 | Cancer Lett. | pmid:9215854 |
| Stein CA | Controversies in the cellular pharmacology of oligodeoxynucleotides. | 1997 | Antisense Nucleic Acid Drug Dev. | pmid:9212912 |
| Yehuda S et al. | Essential fatty acid preparation improves biochemical and cognitive functions in experimental allergic encephalomyelitis rats. | 1997 | Eur. J. Pharmacol. | pmid:9203563 |
| Schut HA et al. | DNA adducts of heterocyclic amines: formation, removal and inhibition by dietary components. | 1997 | Mutat. Res. | pmid:9202755 |
| Sauer LA et al. | Dietary linoleic acid intake controls the arterial blood plasma concentration and the rates of growth and linoleic acid uptake and metabolism in hepatoma 7288CTC in Buffalo rats. | 1997 | J. Nutr. | pmid:9202100 |
| Petrek JA et al. | Fatty acid composition of adipose tissue, an indication of dietary fatty acids, and breast cancer prognosis. | 1997 | J. Clin. Oncol. | pmid:9193329 |
| Sharpe M et al. | Ligation, inhibition, and activation of cytochrome c oxidase by fatty acids. | 1997 | Biochem. Cell Biol. | pmid:9192076 |
| Sanderson P et al. | Dietary fish oil diminishes the antigen presentation activity of rat dendritic cells. | 1997 | Biochem. Soc. Trans. | pmid:9191396 |
| Peres CM et al. | Transference of fatty acids from macrophages to lymphocytes in culture. | 1997 | Biochem. Soc. Trans. | pmid:9191389 |
| Berry H et al. | Excess substrate inhibition of soybean lipoxygenase-1 is mainly oxygen-dependent. | 1997 | FEBS Lett. | pmid:9188786 |
| Ek BA et al. | Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid. | 1997 | Biochim. Biophys. Acta | pmid:9187305 |
| Memoli S et al. | Diffusible melanin-related metabolites are potent inhibitors of lipid peroxidation. | 1997 | Biochim. Biophys. Acta | pmid:9187303 |
| Banfi C et al. | Linoleic acid enhances the secretion of plasminogen activator inhibitor type 1 by HepG2 cells. | 1997 | J. Lipid Res. | pmid:9186904 |
| Ding ST and Lilburn MS | Changes in fatty acid profiles in different lipid classes during late development of turkey embryos from two genetic lines. | 1997 | Poult. Sci. | pmid:9181615 |
| Hornstra G and Kester AD | Effect of the dietary fat type on arterial thrombosis tendency: systematic studies with a rat model. | 1997 | Atherosclerosis | pmid:9180241 |
| Harvei S et al. | Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer. | 1997 | Int. J. Cancer | pmid:9178806 |
| Nakayama T et al. | Lipid peroxidation in linoleic acid micelles caused by H2O2 in the presence of myoglobin. | 1997 | Biosci. Biotechnol. Biochem. | pmid:9178558 |
| Matsusue K et al. | A highly toxic PCB produces unusual changes in the fatty acid composition of rat liver. | 1997 | Toxicol. Lett. | pmid:9175845 |
| Monette M and Lafleur M | Influence of lipid chain unsaturation on melittin-induced micellization. | 1996 | Biophys. J. | pmid:9172743 |
| Palombo JD et al. | Cyclic vs continuous enteral feeding with omega-3 and gamma-linolenic fatty acids: effects on modulation of phospholipid fatty acids in rat lung and liver immune cells. | 1997 May-Jun | JPEN J Parenter Enteral Nutr | pmid:9168366 |