| MeSH term | MeSH ID | Detail |
|---|---|---|
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Hypertension, Renal | D006977 | 9 associated lipids |
| Malabsorption Syndromes | D008286 | 16 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Exocrine Pancreatic Insufficiency | D010188 | 6 associated lipids |
| Dermatitis, Allergic Contact | D017449 | 20 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ivan M et al. | Rumen fermentation and microbial population in lactating dairy cows receiving diets containing oilseeds rich in C-18 fatty acids. | 2013 | Br. J. Nutr. | pmid:22850225 |
| Cheng G et al. | Relative validity of a 3 d estimated food record in German toddlers. | 2013 | Public Health Nutr | pmid:22874634 |
| Anton SD et al. | Differential effects of adulterated versus unadulterated forms of linoleic acid on cardiovascular health. | 2013 | J Integr Med | pmid:23464640 |
| Zhang J et al. | Characteristics of fatty acid distribution is associated with colorectal cancer prognosis. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23465412 |
| Moon C et al. | Modeling sulfate removal by inhibited mesophilic mixed anaerobic communities using a statistical approach. | 2013 | Water Res. | pmid:23466036 |
| Bae WK et al. | Docetaxel-loaded thermoresponsive conjugated linoleic acid-incorporated poloxamer hydrogel for the suppression of peritoneal metastasis of gastric cancer. | 2013 | Biomaterials | pmid:23174142 |
| SuardÃaz R et al. | An insight into the regiospecificity of linoleic acid peroxidation catalyzed by mammalian 15-lipoxygenases. | 2013 | J Phys Chem B | pmid:23496802 |
| Cardoso S et al. | UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats. | 2013 | J. Bioenerg. Biomembr. | pmid:23504111 |
| Stamey Lanier J et al. | Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. | 2013 | Lipids | pmid:23504269 |
| Saubeau G et al. | Differential induction of oxylipin pathway in potato and tobacco cells by bacterial and oomycete elicitors. | 2013 | Plant Cell Rep. | pmid:23479199 |
| Lai MC et al. | The natural PPAR agonist linoleic acid stimulated insulin release in the rat pancreas. | 2013 | J. Vet. Med. Sci. | pmid:23832628 |
| Song Y et al. | Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members. | 2013 | Lipids Health Dis | pmid:23879935 |
| Klein-Wieringa IR et al. | Adipocytes modulate the phenotype of human macrophages through secreted lipids. | 2013 | J. Immunol. | pmid:23817431 |
| Wei J et al. | Linoleic acid attenuates endothelium-derived relaxing factor production by suppressing cAMP-hydrolyzing phosphodiesterase activity. | 2013 | Circ. J. | pmid:23883876 |
| Zhao X et al. | Analysis of fatty acids and phytosterols in ethanol extracts of Nelumbo nucifera seeds and rhizomes by GC-MS. | 2013 | J. Agric. Food Chem. | pmid:23742045 |
| Renner L et al. | Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid, linoleic acid, phytanic acid and the combination of various fatty acids on proliferation and cytokine expression of bovine peripheral blood mononuclear cells. | 2013 | Nutrients | pmid:23857174 |
| Raatz SK et al. | Dose-dependent consumption of farmed Atlantic salmon (Salmo salar) increases plasma phospholipid n-3 fatty acids differentially. | 2013 | J Acad Nutr Diet | pmid:23351633 |
| Lohner S et al. | Gender differences in the long-chain polyunsaturated fatty acid status: systematic review of 51 publications. | 2013 | Ann. Nutr. Metab. | pmid:23327902 |
| MacIntosh BA et al. | Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research. | 2013 | Br. J. Nutr. | pmid:23328113 |
| Graves JP et al. | Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily. | 2013 | Drug Metab. Dispos. | pmid:23315644 |
| Zamora-Rojas E et al. | Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. | 2013 | Meat Sci. | pmid:23793086 |
| Benjamin S et al. | Conjugated linoleic acid isomers and their precursor fatty acids regulate peroxisome proliferator-activated receptor subtypes and major peroxisome proliferator responsive element-bearing target genes in HepG2 cell model. | 2013 | J Zhejiang Univ Sci B | pmid:23365010 |
| Harris WS et al. | Erythrocyte omega-3 fatty acids increase and linoleic acid decreases with age: observations from 160,000 patients. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23375840 |
| Chiou TY et al. | Characteristics and antioxidative ability of defatted rice bran extracts obtained using several extractants under subcritical conditions. | 2013 | J Oleo Sci | pmid:23357811 |
| Zlatanov MD et al. | Lipid composition of Castanea sativa Mill. and Aesculus hippocastanum fruit oils. | 2013 | J. Sci. Food Agric. | pmid:23174908 |
| McPherson PA et al. | Mechanism for the enhanced peroxidation of linoleic acid by a titanium dioxide/hypochlorite system. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23178466 |
| Toral PG et al. | Effect of the inclusion of quebracho tannins in a diet rich in linoleic acid on milk fatty acid composition in dairy ewes. | 2013 | J. Dairy Sci. | pmid:23164228 |
| Yang Z and Huffman SL | Modelling linoleic acid and α-linolenic acid requirements for infants and young children in developing countries. | 2013 | Matern Child Nutr | pmid:23167585 |
| Liu X et al. | Oxidized fatty acid analysis by charge-switch derivatization, selected reaction monitoring, and accurate mass quantitation. | 2013 | Anal. Biochem. | pmid:23850559 |
| Fedor DM et al. | The effect of docosahexaenoic acid on t10, c12-conjugated linoleic acid-induced changes in fatty acid composition of mouse liver, adipose, and muscle. | 2013 | Metab Syndr Relat Disord | pmid:23170930 |
| Ali Q et al. | Ameliorating effects of exogenously applied proline on seed composition, seed oil quality and oil antioxidant activity of maize (Zea mays L.) under drought stress. | 2013 | Int J Mol Sci | pmid:23344043 |
| Chodok P et al. | Identification and functional characterization of two Δ12-fatty acid desaturases associated with essential linoleic acid biosynthesis in Physcomitrella patens. | 2013 | J. Ind. Microbiol. Biotechnol. | pmid:23702573 |
| Benjakul S et al. | Antioxidant activity and inhibitory effects of lead (Leucaena leucocephala) seed extracts against lipid oxidation in model systems. | 2013 | Food Sci Technol Int | pmid:23729420 |
| Katan MB | [Linoleic acid and heart infarct]. | 2013 | Ned Tijdschr Geneeskd | pmid:23714298 |
| Men XM et al. | Age-related changes and nutritional regulation of myosin heavy-chain composition in longissimus dorsi of commercial pigs. | 2013 | Animal | pmid:23764195 |
| Kim JB et al. | Heart failure is associated with impaired anti-inflammatory and antioxidant properties of high-density lipoproteins. | 2013 | Am. J. Cardiol. | pmid:24050409 |
| Cvetković Z et al. | Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. | 2013 | Med. Oncol. | pmid:24085546 |
| Kenny JG et al. | Mannitol utilisation is required for protection of Staphylococcus aureus from human skin antimicrobial fatty acids. | 2013 | PLoS ONE | pmid:23861785 |
| Xie J et al. | A polyethylenimine-linoleic acid conjugate for antisense oligonucleotide delivery. | 2013 | Biomed Res Int | pmid:23862153 |
| Reinders I et al. | Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study. | 2013 | Eur J Clin Nutr | pmid:24084512 |
| Gibson RA et al. | Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22515943 |
| Benbrook CM et al. | Organic production enhances milk nutritional quality by shifting fatty acid composition: a United States-wide, 18-month study. | 2013 | PLoS ONE | pmid:24349282 |
| Ruparel S et al. | Oxidized linoleic acid metabolite-cytochrome P450 system (OLAM-CYP) is active in biopsy samples from patients with inflammatory dental pain. | 2013 | Pain | pmid:23867730 |
| de Oliveira Otto MC et al. | Circulating and dietary omega-3 and omega-6 polyunsaturated fatty acids and incidence of CVD in the Multi-Ethnic Study of Atherosclerosis. | 2013 | J Am Heart Assoc | pmid:24351702 |
| Sisignano M et al. | Synthesis of lipid mediators during UVB-induced inflammatory hyperalgesia in rats and mice. | 2013 | PLoS ONE | pmid:24349046 |
| Yang Y and McClements DJ | Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. | 2013 | J Colloid Interface Sci | pmid:23768725 |
| Del Mar Bibiloni M et al. | Dietary factors associated with subclinical inflammation among girls. | 2013 | Eur J Clin Nutr | pmid:24149444 |
| Vukašinović EL et al. | Diapause induces changes in the composition and biophysical properties of lipids in larvae of the European corn borer, Ostrinia nubilalis (Lepidoptera: Crambidae). | 2013 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:23701990 |
| Layek B and Singh J | Cell penetrating peptide conjugated polymeric micelles as a high performance versatile nonviral gene carrier. | 2013 | Biomacromolecules | pmid:24083483 |
| Luo X et al. | Comparison of enzymatic activity of two linoleic acid isomerases expressed in E. coli. | 2013 | Mol. Biol. Rep. | pmid:24062071 |