Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Heart Failure D006333 36 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Glioma D005910 112 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Lin HH et al. Hormonal Modulation of Pheromone Detection Enhances Male Courtship Success. 2016 Neuron pmid:27263969
Sergeant S et al. Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. 2016 Br. J. Nutr. pmid:26615716
Rosenblat M et al. Nitro-Oleic Acid Reduces J774A.1 Macrophage Oxidative Status and Triglyceride Mass: Involvement of Paraoxonase2 and Triglyceride Metabolizing Enzymes. 2016 Lipids pmid:27344666
Abreu P et al. Contractile function recovery in severely injured gastrocnemius muscle of rats treated with either oleic or linoleic acid. 2016 Exp. Physiol. pmid:27579497
Cinelli G et al. Influence of Maternal Obesity and Gestational Weight Gain on Maternal and Foetal Lipid Profile. 2016 Nutrients pmid:27314385
Kuda O et al. Docosahexaenoic Acid-Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties. 2016 Diabetes pmid:27313314
Bautista LE Calcium and linoleic acid supplements in the prevention of preeclampsia. 2016 Colomb. Med. pmid:27226669
Wang S et al. Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. 2016 Biochem. Biophys. Res. Commun. pmid:26879142
Kot AM et al. Rhodotorula glutinis-potential source of lipids, carotenoids, and enzymes for use in industries. 2016 Appl. Microbiol. Biotechnol. pmid:27209039
Mojumdar EH et al. Stratum corneum lipid matrix: Location of acyl ceramide and cholesterol in the unit cell of the long periodicity phase. 2016 Biochim. Biophys. Acta pmid:27169629