| MeSH term | MeSH ID | Detail |
|---|---|---|
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Acute Coronary Syndrome | D054058 | 11 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Renal Insufficiency, Chronic | D051436 | 9 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Anorexia | D000855 | 8 associated lipids |
| Glucose Intolerance | D018149 | 13 associated lipids |
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Hyperpigmentation | D017495 | 11 associated lipids |
| Pregnancy Complications, Neoplastic | D011252 | 4 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alzate A et al. | Preeclampsia prevention: a case-control study nested in a cohort. | 2015 | Colomb. Med. | pmid:26848195 |
| Alvarruiz A et al. | Quality and Composition of Virgin Olive Oil from Varietties Grown in Castilla-La Mancha (Spain). | 2015 | J Oleo Sci | pmid:26369595 |
| Frenzel E et al. | α1-Antitrypsin Combines with Plasma Fatty Acids and Induces Angiopoietin-like Protein 4 Expression. | 2015 | J. Immunol. | pmid:26363050 |
| Mizuta K et al. | Novel identification of the free fatty acid receptor FFAR1 that promotes contraction in airway smooth muscle. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:26342087 |
| Lands B | Omega-3 PUFAs Lower the Propensity for Arachidonic Acid Cascade Overreactions. | 2015 | Biomed Res Int | pmid:26301244 |
| He J et al. | Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis. | 2015 | Yeast | pmid:26284451 |
| Valenzuela R et al. | Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. | 2015 | Nutrients | pmid:26247968 |
| Tucker RM et al. | No Difference in Perceived Intensity of Linoleic Acid in the Oral Cavity between Obese and Nonobese Individuals. | 2015 | Chem. Senses | pmid:26232811 |
| Evans SJ et al. | Plasma linoleic acid partially mediates the association of bipolar disorder on self-reported mental health scales. | 2015 | J Psychiatr Res | pmid:26228402 |
| Min JS et al. | Monitoring the formation of cholesterol oxidation products in model systems using response surface methodology. | 2015 | Lipids Health Dis | pmid:26201850 |
| Farvid MS et al. | Response to Letters Regarding Article, "Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies". | 2015 | Circulation | pmid:26195494 |
| Lucas M | Letter by Lucas Regarding Articles, "Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies" and "Circulating Omega-6 Polyunsaturated Fatty Acids and Total and Cause-Specific Mortality: The Cardiovascular Health Study". | 2015 | Circulation | pmid:26195492 |
| Hoenselaar R | Letter by Hoenselaar Regarding Article, "Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies". | 2015 | Circulation | pmid:26195491 |
| Yuan T et al. | Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. | 2015 | Int J Clin Exp Pathol | pmid:26191198 |
| Fajardo VA et al. | Cardiolipin linoleic acid content and mitochondrial cytochrome c oxidase activity are associated in rat skeletal muscle. | 2015 | Chem. Phys. Lipids | pmid:25727371 |
| Saccenti E et al. | Strategies for individual phenotyping of linoleic and arachidonic acid metabolism using an oral glucose tolerance test. | 2015 | PLoS ONE | pmid:25786212 |
| Vlachogianni IC et al. | In vitro assessment of antioxidant activity of tyrosol, resveratrol and their acetylated derivatives. | 2015 | Food Chem | pmid:25660873 |
| Yoshida Y et al. | Chemistry of lipid peroxidation products and their use as biomarkers in early detection of diseases. | 2015 | J Oleo Sci | pmid:25766928 |
| Ciepiela P et al. | Arachidonic and linoleic acid derivatives impact oocyte ICSI fertilization--a prospective analysis of follicular fluid and a matched oocyte in a 'one follicle--one retrieved oocyte--one resulting embryo' investigational setting. | 2015 | PLoS ONE | pmid:25763593 |
| Hernandez LR et al. | Effect of plant growth regulators on fatty acids composition in Jatropha curcas L. callus culture. | 2015 | J Oleo Sci | pmid:25757437 |
| Kotani K et al. | Enzymatic preparation of human milk fat substitutes and their oxidation stability. | 2015 | J Oleo Sci | pmid:25757431 |
| Hashim RB et al. | Fatty acid compositions of silver catfish, Pangasius sp. farmed in several rivers of Pahang, Malaysia. | 2015 | J Oleo Sci | pmid:25748380 |
| Chang TS et al. | Palm oil derived trimethylolpropane triesters synthetic lubricants and usage in industrial metalworking fluid. | 2015 | J Oleo Sci | pmid:25748374 |
| Askari M et al. | Tissue fatty acid composition and secretory phospholipase-A2 activity in oral squamous cell carcinoma. | 2015 | Clin Transl Oncol | pmid:25351172 |
| Tyurina YY et al. | LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. | 2015 | Free Radic. Res. | pmid:25740198 |
| Wang S et al. | Plasma nutrient biomarkers are associated with waist-to-height ratio in youth with type 1 diabetes. | 2015 | J. Nutr. | pmid:25733475 |
| Nardi F et al. | Proteasomal modulation of cellular SNAT2 (SLC38A2) abundance and function by unsaturated fatty acid availability. | 2015 | J. Biol. Chem. | pmid:25653282 |
| Clouard C et al. | Dietary linoleic and α-linolenic acids affect anxiety-related responses and exploratory activity in growing pigs. | 2015 | J. Nutr. | pmid:25644359 |
| Fala AM et al. | Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α. | 2015 | Sci Rep | pmid:26237540 |
| Beam J et al. | Excess Linoleic Acid Increases Collagen I/III Ratio and "Stiffens" the Heart Muscle Following High Fat Diets. | 2015 | J. Biol. Chem. | pmid:26240151 |
| Okazaki H et al. | Bongkrekic acid as a selective activator of the peroxisome proliferator-activated receptor γ (PPARγ) isoform. | 2015 | J Toxicol Sci | pmid:25786526 |
| Naughton SS et al. | Australia's nutrition transition 1961-2009: a focus on fats. | 2015 | Br. J. Nutr. | pmid:26123446 |
| Salazar MO et al. | A thin-layer chromatography autographic method for the detection of inhibitors of the Salmonella PhoP-PhoQ regulatory system. | 2014 Mar-Apr | Phytochem Anal | pmid:24185747 |
| Bernhard W et al. | Plasma phospholipids indicate impaired fatty acid homeostasis in preterm infants. | 2014 | Eur J Nutr | pmid:24464176 |
| Corrêa RC et al. | Antioxidant and rheological properties of guava jam with added concentrated grape juice. | 2014 | J. Sci. Food Agric. | pmid:23696312 |
| Tang KS | Protective effect of arachidonic acid and linoleic acid on 1-methyl-4-phenylpyridinium-induced toxicity in PC12 cells. | 2014 | Lipids Health Dis | pmid:25522984 |
| Maruyama H et al. | Linoleate appears to protect against palmitate-induced inflammation in Huh7 cells. | 2014 | Lipids Health Dis | pmid:24885871 |
| Nosaka S and Miyazawa M | Characterization of volatile components and odor-active compounds in the oil of edible mushroom Boletopsis leucomelas. | 2014 | J Oleo Sci | pmid:24881770 |
| Chilton FH et al. | Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases. | 2014 | Nutrients | pmid:24853887 |
| Saito H and Ishikawa S | Lipid classes and fatty acid profile of cultured and wild black rockfish, Sebastes schlegeli. | 2014 | J Oleo Sci | pmid:24829130 |
| Yang B et al. | Synthesis of conjugated linoleic acid by the linoleate isomerase complex in food-derived lactobacilli. | 2014 | J. Appl. Microbiol. | pmid:24750362 |
| Mouokeu RS et al. | Antifungal and antioxidant activity of Crassocephalum bauchiense (Hutch.) Milne-Redh ethyl acetate extract and fractions (Asteraceae). | 2014 | BMC Res Notes | pmid:24742210 |
| Dal Bosco A et al. | Effect of dietary alfalfa on the fatty acid composition and indexes of lipid metabolism of rabbit meat. | 2014 | Meat Sci. | pmid:24036258 |
| Huang FC et al. | Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. | 2014 | Appl. Environ. Microbiol. | pmid:24242247 |
| López A et al. | Compressive mechanical properties and cytocompatibility of bone-compliant, linoleic acid-modified bone cement in a bovine model. | 2014 | J Mech Behav Biomed Mater | pmid:24508711 |
| Bonferoni MC et al. | Ionic polymeric micelles based on chitosan and fatty acids and intended for wound healing. Comparison of linoleic and oleic acid. | 2014 | Eur J Pharm Biopharm | pmid:24384070 |
| González-AbuÃn N et al. | Grape-seed procyanidins modulate cellular membrane potential and nutrient-induced GLP-1 secretion in STC-1 cells. | 2014 | Am. J. Physiol., Cell Physiol. | pmid:24371039 |
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| Matthaus B and Özcan MM | Fatty acid and tocopherol contents of several soybean oils. | 2014 | Nat. Prod. Res. | pmid:24499198 |
| Darling RA et al. | Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. | 2014 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:24760994 |