Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Metabolic Syndrome D024821 44 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Weight Loss D015431 56 associated lipids
Anorexia D000855 8 associated lipids
Glucose Intolerance D018149 13 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Hyperpigmentation D017495 11 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Willett WC Specific fatty acids and risks of breast and prostate cancer: dietary intake. 1997 Am. J. Clin. Nutr. pmid:9394715
Ali I and Steele JE Evidence that free fatty acids in trophocytes of Periplaneta americana fat body may be regulated by the activity of phospholipase A2 and cyclooxygenase. 1997 Insect Biochem. Mol. Biol. pmid:9404012
Gniwotta C et al. Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9409317
van Niel MH and Beynen AC The intake of polyunsaturated fatty acids by cats is reflected in their adipose tissue. 1997 Vet Q pmid:9413110
Kritchevsky D Trans fatty acids and cardiovascular risk. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9430386
Renaud SC Dietary management of cardiovascular diseases. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9430390
Zhou L et al. Tissue uptake and interconversion of plasma unesterified 14C linoleic acid in the guinea pig. 1997 Biochim. Biophys. Acta pmid:9434134
Bylund J et al. Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes. 1998 J. Pharmacol. Exp. Ther. pmid:9435160
Kaur K et al. (Carboxyalkyl)pyrroles in human plasma and oxidized low-density lipoproteins. 1997 Chem. Res. Toxicol. pmid:9437530
Berry H et al. Oxygen concentration determines regiospecificity in soybean lipoxygenase-1 reaction via a branched kinetic scheme. 1998 J. Biol. Chem. pmid:9446584