Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Renal Insufficiency, Chronic D051436 9 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Anorexia D000855 8 associated lipids
Constipation D003248 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Otitis Externa D010032 8 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Melanosis D008548 4 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Per page 10 20 50 100 | Total 75

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Virtanen JK et al. Dietary intake of polyunsaturated fatty acids and risk of hip fracture in men and women. 2012 Osteoporos Int pmid:22270860
Sabir A et al. The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.). 2012 J. Sci. Food Agric. pmid:22271548
Ross GR et al. Fatty acid profile of pig meat after probiotic administration. 2012 J. Agric. Food Chem. pmid:22506842
Ties P and Barringer S Influence of lipid content and lipoxygenase on flavor volatiles in the tomato peel and flesh. 2012 J. Food Sci. pmid:22757705
Morales A et al. Quantitative analysis of hydroperoxy-, keto- and hydroxy-dienes in refined vegetable oils. 2012 J Chromatogr A pmid:22321954
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Honkanen AM et al. Characterization of the disappearance and formation of biohydrogenation intermediates during incubations of linoleic acid with rumen fluid in vitro. 2012 J. Dairy Sci. pmid:22365221
Gutla PV et al. Modulation of plant TPC channels by polyunsaturated fatty acids. 2012 J. Exp. Bot. pmid:23105130
Saei-Dehkordi SS et al. Chemical composition and antioxidative activity of Echinophora platyloba DC. essential oil, and its interaction with natural antimicrobials against food-borne pathogens and spoilage organisms. 2012 J. Food Sci. pmid:23106123
Jernerén F et al. Linolenate 9R-dioxygenase and allene oxide synthase activities of Lasiodiplodia theobromae. 2012 Lipids pmid:22048860
Garcia CV et al. Characterisation of bound volatile compounds of a low flavour kiwifruit species: Actinidia eriantha. 2012 Food Chem pmid:23107675
Beck JJ et al. Generation of the volatile spiroketals conophthorin and chalcogran by fungal spores on polyunsaturated fatty acids common to almonds and pistachios. 2012 J. Agric. Food Chem. pmid:23153034
Jarret RL and Levy IJ Oil and fatty acid contents in seed of Citrullus lanatus Schrad. 2012 J. Agric. Food Chem. pmid:22540530
Banti CN et al. Mixed ligand-silver(I) complexes with anti-inflammatory agents which can bind to lipoxygenase and calf-thymus DNA, modulating their function and inducing apoptosis. 2012 Metallomics pmid:22552402
Little JP et al. The saturated fatty acid palmitate induces human monocytic cell toxicity toward neuronal cells: exploring a possible link between obesity-related metabolic impairments and neuroinflammation. 2012 J. Alzheimers Dis. pmid:22045487
Li J et al. A chitosan induced 9-lipoxygenase in Adelostemma gracillimum seedlings. 2012 Int J Mol Sci pmid:22312270
Sauerwald UC et al. Effect of different levels of docosahexaenoic acid supply on fatty acid status and linoleic and α-linolenic acid conversion in preterm infants. 2012 J. Pediatr. Gastroenterol. Nutr. pmid:22008957
Krugner-Higby L et al. Ulcerative dermatitis in C57BL/6 mice lacking stearoyl CoA desaturase 1. 2012 Comp. Med. pmid:23043777
Han SN et al. Novel soybean oils differing in fatty acid composition alter immune functions of moderately hypercholesterolemic older adults. 2012 J. Nutr. pmid:23096013
Buchhaupt M et al. Synthesis of green note aroma compounds by biotransformation of fatty acids using yeast cells coexpressing lipoxygenase and hydroperoxide lyase. 2012 Appl. Microbiol. Biotechnol. pmid:21789493
King NP et al. Characterisation of a cell wall-anchored protein of Staphylococcus saprophyticus associated with linoleic acid resistance. 2012 BMC Microbiol. pmid:22243671
Zhou H et al. Purification and characterization of a novel ~18 kDa antioxidant protein from Ginkgo biloba seeds. 2012 Molecules pmid:23519252
Georgiadi A et al. Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. 2012 Physiol. Genomics pmid:22274564
Weiss LA et al. The omega-6 fatty acid linoleic acid is associated with risk of gastroschisis: a novel dietary risk factor. 2012 Am. J. Med. Genet. A pmid:22315197
de Goede J et al. Linoleic acid intake, plasma cholesterol and 10-year incidence of CHD in 20,000 middle-aged men and women in the Netherlands. 2012 Br. J. Nutr. pmid:21816117
Sun X et al. Lipid peroxidation and DNA adduct formation in lymphocytes of premenopausal women: Role of estrogen metabolites and fatty acid intake. 2012 Int. J. Cancer pmid:22322480
Matesanz N et al. Linoleic acid increases monocyte chemotaxis and adhesion to human aortic endothelial cells through protein kinase C- and cyclooxygenase-2-dependent mechanisms. 2012 J. Nutr. Biochem. pmid:21840193
Zhu X et al. Release property and antioxidant effectiveness of tocopherol-incorporated LDPE/PP blend films. 2012 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:22257167
Tanaka R et al. Prenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activities. 2012 Adv. Exp. Med. Biol. pmid:22259110
Raatz SK et al. Total dietary fat and fatty acid content modifies plasma phospholipid fatty acids, desaturase activity indices, and urinary prostaglandin E in women. 2012 Nutr Res pmid:22260857
Sandoval-Montemayor NE et al. Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents. 2012 Molecules pmid:22992784
Huang FC and Schwab W Overexpression of hydroperoxide lyase, peroxygenase and epoxide hydrolase in tobacco for the biotechnological production of flavours and polymer precursors. 2012 Plant Biotechnol. J. pmid:22967031
Florence AC et al. Fatty acid profile, trans-octadecenoic, α-linolenic and conjugated linoleic acid contents differing in certified organic and conventional probiotic fermented milks. 2012 Food Chem pmid:22980792
Burstein S et al. N-Amino acid linoleoyl conjugates: anti-inflammatory activities. 2012 Bioorg. Med. Chem. Lett. pmid:22217875
Dundar A et al. Antioxidant properties, chemical composition and nutritional value of Terfezia boudieri (Chatin) from Turkey. 2012 Food Sci Technol Int pmid:22773542
Al-Said MS et al. Edible oils for liver protection: hepatoprotective potentiality of Moringa oleifera seed oil against chemical-induced hepatitis in rats. 2012 J. Food Sci. pmid:22757719
Toomik P et al. The effect of tenderizing acids on linoleic acid oxidation during marination of pork. 2012 Meat Sci. pmid:22762994
Kowalska A et al. Impact of diets with different proportions of linseed and sunflower oils on the growth, liver histology, immunological and chemical blood parameters, and proximate composition of pikeperch Sander lucioperca (L.). 2012 Fish Physiol. Biochem. pmid:21656178
Wadekar SD et al. Microbial synthesis of rhamnolipids by Pseudomonas aeruginosa (ATCC 10145) on waste frying oil as low cost carbon source. 2012 Prep. Biochem. Biotechnol. pmid:22509850
Ling PR et al. Purified fish oil eliminating linoleic and alpha linolenic acid meets essential fatty acid requirements in rats. 2012 Metab. Clin. Exp. pmid:22512821
Tanigai T et al. Docosahexaenoic acid exerts anti-inflammatory action on human eosinophils through peroxisome proliferator-activated receptor-independent mechanisms. 2012 Int. Arch. Allergy Immunol. pmid:22487606
Romano R et al. Comparison of the frying performance of olive oil and palm superolein. 2012 J. Food Sci. pmid:22490166
Manosroi A et al. Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction. 2012 Eur J Pharm Biopharm pmid:22490981
Billault I et al. Probing substrate-product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes. 2012 Anal Bioanal Chem pmid:22349323
Khan R et al. Variation in oil content and fatty acid composition of the seed oil of Acacia species collected from the northwest zone of India. 2012 J. Sci. Food Agric. pmid:22351513
Novak EM et al. Low linoleic acid may facilitate Δ6 desaturase activity and docosahexaenoic acid accretion in human fetal development. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22365109
Santos FS et al. Status of cis and trans fatty acids in Brazilian adolescent mothers and their newborns. 2012 J Pediatr Adolesc Gynecol pmid:22840939
McPherson PA et al. A curvilinear approach to the kinetic analysis of linoleate peroxidation in aqueous liposomes by 2,2'azobis(2-amidoinopropane) dihydrochloride. 2012 Chem. Phys. Lipids pmid:22841574
Sultana B et al. Investigation on the antioxidant activity of leaves, peels, stems bark, and kernel of mango (Mangifera indica L.). 2012 J. Food Sci. pmid:22860576
Okui T et al. Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells. 2011 Sep-Oct Prostaglandins Leukot. Essent. Fatty Acids pmid:21723718