| MeSH term | MeSH ID | Detail |
|---|---|---|
| Endometrial Neoplasms | D016889 | 30 associated lipids |
| Hyperlipidemia, Familial Combined | D006950 | 9 associated lipids |
| Spirochaetales Infections | D013145 | 2 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Melanosis | D008548 | 4 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Genetic Diseases, X-Linked | D040181 | 2 associated lipids |
| Coronary Restenosis | D023903 | 10 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Circoviridae Infections | D018173 | 2 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Song E et al. | Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice. | 2014 | J Am Heart Assoc | pmid:24721803 |
| Petrogianni M et al. | Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention. | 2014 | Public Health Nutr | pmid:23249766 |
| Armstrong EH et al. | Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway. | 2014 | J. Biol. Chem. | pmid:24692551 |
| Petzinger C et al. | Lipid metabolic dose response to dietary alpha-linolenic acid in monk parrot (Myiopsitta monachus). | 2014 | Lipids | pmid:24293226 |
| Hodson L et al. | Plasma and erythrocyte fatty acids reflect intakes of saturated and n-6 PUFA within a similar time frame. | 2014 | J. Nutr. | pmid:24225449 |
| Baek JH et al. | Lithium tremor revisited: pathophysiology and treatment. | 2014 | Acta Psychiatr Scand | pmid:23834617 |
| Bagai S et al. | Lipid-modified polyethylenimine-mediated DNA attraction evaluated by molecular dynamics simulations. | 2014 | J Phys Chem B | pmid:24918771 |
| Tang KS | Protective effect of arachidonic acid and linoleic acid on 1-methyl-4-phenylpyridinium-induced toxicity in PC12 cells. | 2014 | Lipids Health Dis | pmid:25522984 |
| Qin G et al. | Evolution of the aroma volatiles of pear fruits supplemented with fatty acid metabolic precursors. | 2014 | Molecules | pmid:25474290 |
| Mesti T et al. | Metabolic impact of anti-angiogenic agents on U87 glioma cells. | 2014 | PLoS ONE | pmid:24922514 |
| Herchi W et al. | Flaxseed hull: Chemical composition and antioxidant activity during development. | 2014 | J Oleo Sci | pmid:24919478 |
| Woyda-Ploszczyca AM and Jarmuszkiewicz W | Different effects of guanine nucleotides (GDP and GTP) on protein-mediated mitochondrial proton leak. | 2014 | PLoS ONE | pmid:24904988 |
| Maruyama H et al. | Linoleate appears to protect against palmitate-induced inflammation in Huh7 cells. | 2014 | Lipids Health Dis | pmid:24885871 |
| Nosaka S and Miyazawa M | Characterization of volatile components and odor-active compounds in the oil of edible mushroom Boletopsis leucomelas. | 2014 | J Oleo Sci | pmid:24881770 |
| Chilton FH et al. | Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases. | 2014 | Nutrients | pmid:24853887 |
| Saito H and Ishikawa S | Lipid classes and fatty acid profile of cultured and wild black rockfish, Sebastes schlegeli. | 2014 | J Oleo Sci | pmid:24829130 |
| Morris JB et al. | Flavonol content, oil%, and fatty acid composition variability in seeds of Teramnus labialis and T. uncinatus accessions with nutraceutical potential. | 2014 | J Diet Suppl | pmid:25054688 |
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| Yang B et al. | Synthesis of conjugated linoleic acid by the linoleate isomerase complex in food-derived lactobacilli. | 2014 | J. Appl. Microbiol. | pmid:24750362 |
| Mouokeu RS et al. | Antifungal and antioxidant activity of Crassocephalum bauchiense (Hutch.) Milne-Redh ethyl acetate extract and fractions (Asteraceae). | 2014 | BMC Res Notes | pmid:24742210 |
| Buehlmann C et al. | Desert ants locate food by combining high sensitivity to food odors with extensive crosswind runs. | 2014 | Curr. Biol. | pmid:24726153 |
| Arcan I and YemenicioÄŸlu A | Controlled release properties of zein-fatty acid blend films for multiple bioactive compounds. | 2014 | J. Agric. Food Chem. | pmid:25025594 |
| Mouradian M et al. | Key roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth. | 2014 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24374147 |
| Nehdi IA et al. | Chamaerops humilis L. var. argentea André date palm seed oil: a potential dietetic plant product. | 2014 | J. Food Sci. | pmid:24666023 |
| Santos S et al. | Fatty acids derived from a food frequency questionnaire and measured in the erythrocyte membrane in relation to adiponectin and leptin concentrations. | 2014 | Eur J Clin Nutr | pmid:24642786 |
| Sarath Josh MK et al. | Phthalates efficiently bind to human peroxisome proliferator activated receptor and retinoid X receptor α, β, γ subtypes: an in silico approach. | 2014 | J Appl Toxicol | pmid:23843199 |
| Negrini R et al. | Influence of electrostatic interactions on the release of charged molecules from lipid cubic phases. | 2014 | Langmuir | pmid:24673189 |
| Choque B et al. | Linoleic acid: between doubts and certainties. | 2014 | Biochimie | pmid:23900039 |
| Radice M et al. | Chemical characterization and antioxidant activity of Amazonian (Ecuador) Caryodendron orinocense Karst. and Bactris gasipaes Kunth seed oils. | 2014 | J Oleo Sci | pmid:25391685 |
| Garrel G et al. | Unsaturated fatty acids disrupt Smad signaling in gonadotrope cells leading to inhibition of FSHβ gene expression. | 2014 | Endocrinology | pmid:24248462 |
| Kim JY et al. | Role of moisture on the lipid oxidation determined by D(2)O in a linoleic acid model system. | 2014 | Food Chem | pmid:24176324 |
| Usami A et al. | Characteristic odorants from bailingu oyster mushroom (Pleurotus eryngii var. tuoliensis) and summer oyster mushroom (Pleurotus cystidiosus). | 2014 | J Oleo Sci | pmid:24919476 |
| Sponton OE et al. | Effect of limited enzymatic hydrolysis on linoleic acid binding properties of β-lactoglobulin. | 2014 | Food Chem | pmid:24176383 |
| Su MH et al. | Chemical composition of seed oils in native Taiwanese Camellia species. | 2014 | Food Chem | pmid:24629982 |
| Yavin E et al. | Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency. | 2014 | Biochim. Biophys. Acta | pmid:24960100 |
| Huang FC et al. | Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. | 2014 | Appl. Environ. Microbiol. | pmid:24242247 |
| Yang Y et al. | Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. | 2014 | Lipids | pmid:24777581 |
| Shimizu N et al. | De novo biosynthesis of linoleic acid and its conversion to the hydrocarbon (Z,Z)-6,9-heptadecadiene in the astigmatid mite, Carpoglyphus lactis: incorporation experiments with 13C-labeled glucose. | 2014 | Insect Biochem. Mol. Biol. | pmid:24333472 |
| Reiner WB et al. | Fatty acids in mountain gorilla diets: implications for primate nutrition and health. | 2014 | Am. J. Primatol. | pmid:24243235 |
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| Choi JS et al. | In vivo hair growth-promoting effect of rice bran extract prepared by supercritical carbon dioxide fluid. | 2014 | Biol. Pharm. Bull. | pmid:24389480 |
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| Ozdener MH et al. | CD36- and GPR120-mediated Ca²⺠signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice. | 2014 | Gastroenterology | pmid:24412488 |
| Hoffman LC et al. | Lipid and protein stability and sensory evaluation of ostrich (Struthio camelus) droëwors with the addition of rooibos tea extract (Aspalathus linearis) as a natural antioxidant. | 2014 | Meat Sci. | pmid:24334052 |
| Canetti L et al. | Linoleic and alpha linolenic acids ameliorate streptozotocin-induced diabetes in mice. | 2014 | Arch. Physiol. Biochem. | pmid:24320056 |
| Kwon B et al. | Oleate prevents palmitate-induced mitochondrial dysfunction, insulin resistance and inflammatory signaling in neuronal cells. | 2014 | Biochim. Biophys. Acta | pmid:24732014 |
| Breiden B and Sandhoff K | The role of sphingolipid metabolism in cutaneous permeability barrier formation. | 2014 | Biochim. Biophys. Acta | pmid:23954553 |
| Darling RA et al. | Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors. | 2014 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:24760994 |
| Hall TD et al. | Changes during leaf expansion of ΦPSII temperature optima in Gossypium hirsutum are associated with the degree of fatty acid lipid saturation. | 2014 | J. Plant Physiol. | pmid:24594393 |