| MeSH term | MeSH ID | Detail |
|---|---|---|
| Endometrial Neoplasms | D016889 | 30 associated lipids |
| Hyperlipidemia, Familial Combined | D006950 | 9 associated lipids |
| Spirochaetales Infections | D013145 | 2 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Melanosis | D008548 | 4 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Genetic Diseases, X-Linked | D040181 | 2 associated lipids |
| Coronary Restenosis | D023903 | 10 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Circoviridae Infections | D018173 | 2 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Reed S et al. | Dietary zinc deficiency affects blood linoleic acid: dihomo-γ-linolenic acid (LA:DGLA) ratio; a sensitive physiological marker of zinc status in vivo (Gallus gallus). | 2014 | Nutrients | pmid:24658588 |
| Huang X et al. | Serum and adipose tissue fatty acid composition as biomarkers of habitual dietary fat intake in elderly men with chronic kidney disease. | 2014 | Nephrol. Dial. Transplant. | pmid:23229929 |
| Bernhard W et al. | Plasma phospholipids indicate impaired fatty acid homeostasis in preterm infants. | 2014 | Eur J Nutr | pmid:24464176 |
| Ebrahimi M et al. | Effects of oils rich in linoleic and α-linolenic acids on fatty acid profile and gene expression in goat meat. | 2014 | Nutrients | pmid:25255382 |
| Xu QY et al. | Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats. | 2014 | Acta Pharmacol. Sin. | pmid:25220639 |
| Victoria FN et al. | Antioxidant and antidepressant-like activities of semi-synthetic α-phenylseleno citronellal. | 2014 | Eur. J. Pharmacol. | pmid:25218989 |
| Farvid MS et al. | Dietary linoleic acid and risk of coronary heart disease: a systematic review and meta-analysis of prospective cohort studies. | 2014 | Circulation | pmid:25161045 |
| Harris WS and Shearer GC | Omega-6 fatty acids and cardiovascular disease: friend, not foe? | 2014 | Circulation | pmid:25161044 |
| Saito HE et al. | Incorporation of exogenous fatty acids protects Enterococcus faecalis from membrane-damaging agents. | 2014 | Appl. Environ. Microbiol. | pmid:25128342 |
| Wu JH et al. | Circulating omega-6 polyunsaturated fatty acids and total and cause-specific mortality: the Cardiovascular Health Study. | 2014 | Circulation | pmid:25124495 |
| Phan CW et al. | Intrastrain comparison of the chemical composition and antioxidant activity of an edible mushroom, Pleurotus giganteus, and its potent neuritogenic properties. | 2014 | ScientificWorldJournal | pmid:25121118 |
| Purushothaman D et al. | Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs. | 2014 | Genet. Mol. Res. | pmid:25078588 |
| van Schalkwijk DB et al. | Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation. | 2014 | PLoS ONE | pmid:25049048 |
| BuÄek A et al. | Δ12-Fatty acid desaturase from Candida parapsilosis is a multifunctional desaturase producing a range of polyunsaturated and hydroxylated fatty acids. | 2014 | PLoS ONE | pmid:24681902 |
| Rodriguez MA et al. | Concordance analysis between estimation methods of milk fatty acid content. | 2014 | Food Chem | pmid:24629954 |
| Spartano NL et al. | Linoleic acid suppresses cholesterol efflux and ATP-binding cassette transporters in murine bone marrow-derived macrophages. | 2014 | Lipids | pmid:24595513 |
| Scalerandi MV et al. | Effect of conjugated linoleic acid mixtures and different edible oils in body composition and lipid regulation in mice. | 2014 | Nutr Hosp | pmid:24559004 |
| Nadtochiy SM et al. | Mitochondrially targeted nitro-linoleate: a new tool for the study of cardioprotection. | 2014 | Br. J. Pharmacol. | pmid:24102583 |
| Choi JI et al. | Development of microalga Scenedesmus dimorphus mutant with higher lipid content by radiation breeding. | 2014 | Bioprocess Biosyst Eng | pmid:24871276 |
| Guo HH et al. | XsFAD2 gene encodes the enzyme responsible for the high linoleic acid content in oil accumulated in Xanthoceras sorbifolia seeds. | 2014 | J. Sci. Food Agric. | pmid:23775588 |
| Huang X et al. | Serum fatty acid patterns, insulin sensitivity and the metabolic syndrome in individuals with chronic kidney disease. | 2014 | J. Intern. Med. | pmid:24011327 |
| Dal Bosco A et al. | Effect of dietary alfalfa on the fatty acid composition and indexes of lipid metabolism of rabbit meat. | 2014 | Meat Sci. | pmid:24036258 |
| Alvheim AR et al. | Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet. | 2014 | Lipids | pmid:24081493 |
| López-Cervantes J et al. | Effect of solvents and methods of stirring in extraction of lycopene, oleoresin and fatty acids from over-ripe tomato. | 2014 | Int J Food Sci Nutr | pmid:24111501 |
| Bakır T et al. | Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2. | 2014 | Int J Food Sci Nutr | pmid:24152374 |
| Wennman A et al. | Kinetic investigation of the rate-limiting step of manganese- and iron-lipoxygenases. | 2014 | Arch. Biochem. Biophys. | pmid:24857825 |
| López A et al. | Compressive mechanical properties and cytocompatibility of bone-compliant, linoleic acid-modified bone cement in a bovine model. | 2014 | J Mech Behav Biomed Mater | pmid:24508711 |
| Larsson N et al. | Lipid mediator profiles differ between lung compartments in asthmatic and healthy humans. | 2014 | Eur. Respir. J. | pmid:24036245 |
| Yang Q et al. | Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds. | 2014 | BMC Complement Altern Med | pmid:25252789 |
| Wu MH et al. | A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. | 2014 | Sci Rep | pmid:24651079 |
| Chevrot M et al. | Obesity interferes with the orosensory detection of long-chain fatty acids in humans. | 2014 | Am. J. Clin. Nutr. | pmid:24522446 |
| Barua P et al. | Seed oils from non-conventional sources in north-east India: potential feedstock for production of biodiesel. | 2014 | Nat. Prod. Res. | pmid:24483850 |
| Matthaus B and Özcan MM | Fatty acid and tocopherol contents of several soybean oils. | 2014 | Nat. Prod. Res. | pmid:24499198 |
| Paulsen SJ et al. | Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion. | 2014 | PLoS ONE | pmid:24520357 |
| Youn K et al. | Oleic acid and linoleic acid from Tenebrio molitor larvae inhibit BACE1 activity in vitro: molecular docking studies. | 2014 | J Med Food | pmid:24548007 |
| Ambrozova JV et al. | Influence of extractive solvents on lipid and fatty acids content of edible freshwater algal and seaweed products, the green Microalga Chlorella kessleri and the Cyanobacterium Spirulina platensis. | 2014 | Molecules | pmid:24566307 |
| Bazongo P et al. | Characteristics, composition and oxidative stability of Lannea microcarpa seed and seed oil. | 2014 | Molecules | pmid:24566330 |
| Nardi F et al. | Enhanced insulin sensitivity associated with provision of mono and polyunsaturated fatty acids in skeletal muscle cells involves counter modulation of PP2A. | 2014 | PLoS ONE | pmid:24632852 |
| Mahendran Y et al. | Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes. | 2014 | Am. J. Clin. Nutr. | pmid:24153340 |
| Ogorodnikova AV et al. | Screening of divinyl ether synthase activity in nonphotosynthetic tissue of asparagales. | 2013 Mar-Apr | Dokl. Biochem. Biophys. | pmid:23657662 |
| Thomas CP et al. | Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis. | 2013 Feb-Mar | Chem. Phys. Lipids | pmid:23352713 |
| Chukir T et al. | Shared retronasal identifications of vapor-phase 18-carbon fatty acids. | 2013 | Chem. Senses | pmid:23424022 |
| McGowan MM et al. | A proof of principle clinical trial to determine whether conjugated linoleic acid modulates the lipogenic pathway in human breast cancer tissue. | 2013 | Breast Cancer Res. Treat. | pmid:23417336 |
| Zuo R et al. | Effects of conjugated linoleic acid on growth, non-specific immunity, antioxidant capacity, lipid deposition and related gene expression in juvenile large yellow croaker (Larmichthys crocea) fed soyabean oil-based diets. | 2013 | Br. J. Nutr. | pmid:23452520 |
| Liu Q et al. | Nonsense-mediated mRNA degradation of CtFAD2-1 and development of a perfect molecular marker for olol mutation in high oleic safflower (Carthamus tinctorius L.). | 2013 | Theor. Appl. Genet. | pmid:23695179 |
| Fijlstra M et al. | Reduced absorption of long-chain fatty acids during methotrexate-induced gastrointestinal mucositis in the rat. | 2013 | Clin Nutr | pmid:23102689 |
| Daud AZ et al. | The trans fatty acid content in human milk and its association with maternal diet among lactating mothers in Malaysia. | 2013 | Asia Pac J Clin Nutr | pmid:23945414 |
| Li KC et al. | [A preliminary study of the inhibitive efficacy of iodized linoleic acid and its fluorodeoxyuridine ester in hepatocellular cancer]. | 2013 | Zhonghua Gan Zang Bing Za Zhi | pmid:24025140 |
| Smink W et al. | Effect of intake of linoleic acid and α-linolenic acid levels on conversion into long-chain polyunsaturated fatty acids in backfat and in intramuscular fat of growing pigs. | 2013 | J Anim Physiol Anim Nutr (Berl) | pmid:22463497 |
| Peters BD et al. | Polyunsaturated fatty acid concentration predicts myelin integrity in early-phase psychosis. | 2013 | Schizophr Bull | pmid:22927668 |