Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Endometrial Neoplasms D016889 30 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Helicobacter Infections D016481 21 associated lipids
Melanosis D008548 4 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Coronary Restenosis D023903 10 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Circoviridae Infections D018173 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Mutanen M and Freese R Polyunsaturated fatty acids and platelet aggregation. 1996 Curr. Opin. Lipidol. pmid:8925182
Mensink R Essential and trans-fatty acids. 1996 Curr. Opin. Lipidol. pmid:8925181
Godley PA et al. Biomarkers of essential fatty acid consumption and risk of prostatic carcinoma. 1996 Cancer Epidemiol. Biomarkers Prev. pmid:8922296
Cunnane SC and Likhodii SS 13C NMR spectroscopy and gas chromatograph--combustion--isotope ratio mass spectrometry: complementary applications in monitoring the metabolism of 13C-labelled polyunsaturated fatty acids. 1996 Can. J. Physiol. Pharmacol. pmid:8909789
Cunnane SC The Canadian Society for Nutritional Sciences 1995 Young Scientist Award Lecture. Recent studies on the synthesis, beta-oxidation, and deficiency of linoleate and alpha-linolenate: are essential fatty acids more aptly named indispensable or conditionally dispensable fatty acids? 1996 Can. J. Physiol. Pharmacol. pmid:8909772
Avery SV et al. Copper toxicity towards Saccharomyces cerevisiae: dependence on plasma membrane fatty acid composition. 1996 Appl. Environ. Microbiol. pmid:8899983
Luukkainen P et al. Impact of solid food on plasma arachidonic and docosahexaenoic acid status of term infants at 8 months of age. 1996 J. Pediatr. Gastroenterol. Nutr. pmid:8890071
Peet M et al. Essential fatty acid deficiency in erythrocyte membranes from chronic schizophrenic patients, and the clinical effects of dietary supplementation. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8888126
Eder K and Kirchgessner M Zinc deficiency and the desaturation of linoleic acid in rats force-fed fat-free diets. 1996 Biol Trace Elem Res pmid:8886317
Engels F et al. Preferential formation of 13-hydroxylinoleic acid by human peripheral blood eosinophils. 1996 Prostaglandins pmid:8880897
Lammoglia MA et al. Effects of dietary fat and season on steroid hormonal profiles before parturition and on hormonal, cholesterol, triglycerides, follicular patterns, and postpartum reproduction in Brahman cows. 1996 J. Anim. Sci. pmid:8880430
Godessart N et al. Prostaglandin H-synthase-2 is the main enzyme involved in the biosynthesis of octadecanoids from linoleic acid in human dermal fibroblasts stimulated with interleukin-1beta. 1996 J. Invest. Dermatol. pmid:8875957
Belury MA et al. Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion. 1996 Nutr Cancer pmid:8875552
Schingoethe DJ et al. Lactational responses of dairy cows fed unsaturated fat from extruded soybeans or sunflower seeds. 1996 J. Dairy Sci. pmid:8872718
Schurz HH et al. Products of aniline and triglycerides in oil samples associated with the toxic oil syndrome. 1996 Chem. Res. Toxicol. pmid:8870988
Hudson JA et al. Hydration of oleic acid by a Selenomonas strain from the ovine rumen. 1996 Lett. Appl. Microbiol. pmid:8862016
Venuta A et al. Essential fatty acids: the effects of dietary supplementation among children with recurrent respiratory infections. 1996 Jul-Aug J. Int. Med. Res. pmid:8854285
Glickman MH and Klinman JP Lipoxygenase reaction mechanism: demonstration that hydrogen abstraction from substrate precedes dioxygen binding during catalytic turnover. 1996 Biochemistry pmid:8841132
Boyd NF et al. Long-term effects of participation in a randomized trial of a low-fat, high-carbohydrate diet. 1996 Cancer Epidemiol. Biomarkers Prev. pmid:8833622
Engberg RM et al. Inclusion of oxidized vegetable oil in broiler diets. Its influence on nutrient balance and on the antioxidative status of broilers. 1996 Poult. Sci. pmid:8829233