Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Endometrial Neoplasms D016889 30 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Helicobacter Infections D016481 21 associated lipids
Melanosis D008548 4 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Coronary Restenosis D023903 10 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Circoviridae Infections D018173 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Iwase H et al. Effect of cytochrome c on the linoleic acid-degrading activity of porcine leukocyte 12-lipoxygenase. 2000 Free Radic. Biol. Med. pmid:10802222
Gupta SV and Khosla P Pork fat and chicken fat similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. 2000 J. Nutr. pmid:10801922
Itokazu N et al. Bidirectional actions of docosahexaenoic acid on hippocampal neurotransmissions in vivo. 2000 Brain Res. pmid:10799687
Kaya A Properties and stability of butter oil obtained from milk and yoghurt. 2000 Nahrung pmid:10795582
Mandin O et al. Volatile compounds from potato-like model systems. 1999 J. Agric. Food Chem. pmid:10794636
McEvoy TG et al. Fatty acid composition of lipids in immature cattle, pig and sheep oocytes with intact zona pellucida. 2000 J. Reprod. Fertil. pmid:10793638
McCarty MF Toward a wholly nutritional therapy for type 2 diabetes. 2000 Med. Hypotheses pmid:10783493
Charnock JS Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780878
Hover CG and Kulkarni AP A simple and efficient method for hemoglobin removal from mammalian tissue cytosol by zinc sulfate and its application to the study of lipoxygenase. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780874
Talcott ST et al. Antioxidant changes and sensory properties of carrot puree processed with and without periderm tissue. 2000 J. Agric. Food Chem. pmid:10775391
Liégeois C et al. Measuring antioxidant efficiency of wort, malt, and hops against the 2,2'-azobis(2-amidinopropane) dihydrochloride-induced oxidation of an aqueous dispersion of linoleic acid. 2000 J. Agric. Food Chem. pmid:10775361
Sasaki T et al. Dietary docosahexaenoic acid can alter the surface expression of CD4 and CD8 on T cells in peripheral blood. 2000 J. Agric. Food Chem. pmid:10775347
Siefken W et al. Regulation of cholesterol synthesis by oleic and palmitic acid in keratinocytes. 2000 Exp. Dermatol. pmid:10772388
Kritharides L Ascorbic acid and copper in linoleate oxidation--Dunkley revisited. 1999 Redox Rep. pmid:10772064
Mogul R et al. Oleyl sulfate reveals allosteric inhibition of soybean lipoxygenase-1 and human 15-lipoxygenase. 2000 Biochemistry pmid:10769137
Littman ED et al. Role of protein kinase C isoenzymes in fatty acid stimulation of insulin secretion. 2000 Pancreas pmid:10766451
Mohan IK and Das UN Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10765977
Punchard NA et al. Analysis of the intestinal absorption of essential fatty acids in vivo in the rat. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10765976
Hubbard NE et al. Reduction of murine mammary tumor metastasis by conjugated linoleic acid. 2000 Cancer Lett. pmid:10755392
Trimborn M et al. Linoleic acid cytotoxicity to bovine lens epithelial cells: influence of albumin on linoleic acid uptake and cytotoxicity. 2000 Mar-Jun Ophthalmic Res. pmid:10754440