Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

Cross Reference

Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Endometrial Neoplasms D016889 30 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Helicobacter Infections D016481 21 associated lipids
Melanosis D008548 4 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Coronary Restenosis D023903 10 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Circoviridae Infections D018173 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Qian SY et al. EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations. 2000 Free Radic. Biol. Med. pmid:11025200
Meaney CM and O'Driscoll CM A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt:fatty acid micellar systems using the CaCo-2 cell culture model. 2000 Int J Pharm pmid:11036226
Smith HL et al. Development of a serum-free system for the in vitro cultivation of Brugia malayi infective-stage larvae. 2000 Exp. Parasitol. pmid:11038308
French SJ et al. The effects of intestinal infusion of long-chain fatty acids on food intake in humans. 2000 Gastroenterology pmid:11040181
Moran JH et al. Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s. 2000 Toxicol. Appl. Pharmacol. pmid:11042099
Soriano CR et al. Cutaneous application of vegetable oil as a coadjutant in the nutritional management of preterm infants. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:11045835
Steinkamp G et al. Energy supplements rich in linoleic acid improve body weight and essential fatty acid status of cystic fibrosis patients. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:11045840
Whigham LD et al. Conjugated linoleic acid: implications for human health. 2000 Pharmacol. Res. pmid:11058400
Surai PF et al. Effect of long-term supplementation with arachidonic or docosahexaenoic acids on sperm production in the broiler chicken. 2000 J. Reprod. Fertil. pmid:11058441
Cunnane SC et al. Specific linoleate deficiency in the rat does not prevent substantial carbon recycling from [(14)C]linoleate into sterols. 2000 J. Lipid Res. pmid:11060350