| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphopenia | D008231 | 2 associated lipids |
| Pneumonia, Viral | D011024 | 3 associated lipids |
| Constipation | D003248 | 8 associated lipids |
| Community-Acquired Infections | D017714 | 8 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rogers AE | Diet and breast cancer: studies in laboratory animals. | 1997 | J. Nutr. | pmid:9164267 |
| Salomaa VV et al. | Association of the fatty acid composition of serum phospholipids with hemostatic factors. | 1997 | Arterioscler. Thromb. Vasc. Biol. | pmid:9157941 |
| Luthria DL et al. | Metabolites produced during the peroxisomal beta-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9144553 |
| Cunnane SC and Anderson MJ | Pure linoleate deficiency in the rat: influence on growth, accumulation of n-6 polyunsaturates, and [1-14C]linoleate oxidation. | 1997 | J. Lipid Res. | pmid:9144095 |
| Bourre JM et al. | Possible role of the choroid plexus in the supply of brain tissue with polyunsaturated fatty acids. | 1997 | Neurosci. Lett. | pmid:9132678 |
| Schneider C et al. | A fatty acid alpha-ketol, a product of the plant lipoxygenase pathway, is oxidized to 3(Z)-dodecendioic acid by a bacterial monooxygenase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9125182 |
| Ip C and Scimeca JA | Conjugated linoleic acid and linoleic acid are distinctive modulators of mammary carcinogenesis. | 1997 | Nutr Cancer | pmid:9121939 |
| Nieuwenhuizen WF et al. | Lipoxygenase is irreversibly inactivated by the hydroperoxides formed from the enynoic analogues of linoleic acid. | 1997 | Biochemistry | pmid:9109655 |
| Griffiths G et al. | Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. | 1997 | Prostate | pmid:9108883 |
| Nishizaki T et al. | Short-term depression and long-term enhancement of ACh-gated channel currents induced by linoleic and linolenic acid. | 1997 | Brain Res. | pmid:9099812 |
| Hayes KC | The linoleic acid content of test diets must be carefully monitored in cholesterol studies. | 1997 | Am. J. Clin. Nutr. | pmid:9094899 |
| Yamaki T et al. | Acute and reversible fatty metamorphosis of cultured rat hepatocytes. | 1997 Feb-Mar | Pathol. Int. | pmid:9088028 |
| Iwase H et al. | Formation of leukotoxin (9,10-epoxy-12-octadecenoic acid) during the autoxidation of phospholipids promoted by hemoproteins. | 1997 | Biochim. Biophys. Acta | pmid:9084498 |
| Iwase H et al. | Effect of monochlorohydrins of linoleic acid on guinea-pig cardiac papillary muscles. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9070266 |
| Reddy N et al. | Characterization of a 15-lipoxygenase in human breast carcinoma BT-20 cells: stimulation of 13-HODE formation by TGF alpha/EGF. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9070230 |
| Butler M et al. | Unsaturated fatty acids enhance cell yields and perturb the energy metabolism of an antibody-secreting hybridoma. | 1997 | Biochem. J. | pmid:9065785 |
| Patel RP et al. | Reduction of Cu(II) by lipid hydroperoxides: implications for the copper-dependent oxidation of low-density lipoprotein. | 1997 | Biochem. J. | pmid:9065759 |
| Roy SK and Kulkarni AP | Isolation and some properties of dioxygenase and co-oxidase activities of adult human liver cytosolic lipoxygenase. | 1996 | J. Biochem. Toxicol. | pmid:9062846 |
| Kühn H et al. | In vivo action of 15-lipoxygenase in early stages of human atherogenesis. | 1997 | J. Clin. Invest. | pmid:9062346 |
| Das I et al. | Effects of aspirin and garlic on cyclooxygenase-induced chemiluminescence in human term placenta. | 1997 | Biochem. Soc. Trans. | pmid:9056997 |