| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphopenia | D008231 | 2 associated lipids |
| Pneumonia, Viral | D011024 | 3 associated lipids |
| Constipation | D003248 | 8 associated lipids |
| Community-Acquired Infections | D017714 | 8 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hatch GM and McClarty G | Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5'-triphosphate. | 1996 | J. Biol. Chem. | pmid:8824210 |
| Toborek M et al. | Linoleic acid and TNF-alpha cross-amplify oxidative injury and dysfunction of endothelial cells. | 1996 | J. Lipid Res. | pmid:8820108 |
| Kaneko T et al. | Cytotoxicity of phosphatidylcholine hydroperoxides is exerted through decomposition of fatty acid hydroperoxide moiety. | 1996 | Free Radic. Biol. Med. | pmid:8818632 |
| Mizushina Y et al. | Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro. | 1996 | Biochim. Biophys. Acta | pmid:8809118 |
| Hörnsten L et al. | Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes. | 1996 | Arch. Biochem. Biophys. | pmid:8806734 |
| Yamada Y et al. | Production of hydroxy fatty acid (10-hydroxy-12(Z)-octadecenoic acid) by Lactobacillus plantarum from linoleic acid and its cardiac effects to guinea pig papillary muscles. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8806645 |
| Porkkala-Sarataho E et al. | Increased oxidation resistance of atherogenic plasma lipoproteins at high vitamin E levels in non-vitamin E supplemented men. | 1996 | Atherosclerosis | pmid:8800496 |
| Carnielli VP et al. | The very low birth weight premature infant is capable of synthesizing arachidonic and docosahexaenoic acids from linoleic and linolenic acids. | 1996 | Pediatr. Res. | pmid:8798265 |
| Ain Baziz H et al. | Chronic heat exposure enhances fat deposition and modifies muscle and fat partition in broiler carcasses. | 1996 | Poult. Sci. | pmid:8786940 |
| Fellner V et al. | Steady-state rates of linoleic acid biohydrogenation by ruminal bacteria in continuous culture. | 1995 | J. Dairy Sci. | pmid:8786265 |
| Connolly JM et al. | Dietary linoleic acid-stimulated human breast cancer cell growth and metastasis in nude mice and their suppression by indomethacin, a cyclooxygenase inhibitor. | 1996 | Nutr Cancer | pmid:8771566 |
| Aoshima H | Potentiation and inhibition of ionotropic neurotransmitter receptors expressed in Xenopus oocyte by linoleic acid and its hydroperoxide. | 1996 | J. Neurochem. | pmid:8769897 |
| Wiesner R et al. | Nitric oxide oxidises a ferrous mammalian lipoxygenase to a pre-activated ferric species. | 1996 | FEBS Lett. | pmid:8766705 |
| Hrboticky N et al. | Linoleic acid esterified in low density lipoprotein serves as substrate for increased arachidonic acid synthesis in differentiating monocytic cells. | 1996 | Biochim. Biophys. Acta | pmid:8765140 |
| Moghaddam M et al. | Novel metabolic pathways for linoleic and arachidonic acid metabolism. | 1996 | Biochim. Biophys. Acta | pmid:8765137 |
| Dunham WR et al. | Oleic acid and linoleic acid are the major determinants of changes in keratinocyte plasma membrane viscosity. | 1996 | J. Invest. Dermatol. | pmid:8751966 |
| Murai A et al. | Role of dietary gamma-linolenic acid in liver lipid metabolism in Japanese quail. | 1995 | Br. Poult. Sci. | pmid:8746984 |
| Jenkins TC et al. | Butylsoyamide increases unsaturation of fatty acids in plasma and milk of lactating dairy cows. | 1996 | J. Dairy Sci. | pmid:8744223 |
| Campbell FM and Dutta-Roy AK | Asymmetric distribution of the plasma membrane fatty acid-binding protein (FABPpm) in the human placenta. | 1996 | Biochem. Soc. Trans. | pmid:8736907 |
| Chaloner C et al. | Effect of oral supplementation with micronutrient antioxidants on trans fatty acid content of lipoproteins in healthy humans. | 1996 | Biochem. Soc. Trans. | pmid:8736849 |