| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphopenia | D008231 | 2 associated lipids |
| Pneumonia, Viral | D011024 | 3 associated lipids |
| Constipation | D003248 | 8 associated lipids |
| Community-Acquired Infections | D017714 | 8 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Griffin ME et al. | Non-insulin-dependent diabetes mellitus: dietary monounsaturated fatty acids and low-density lipoprotein composition and function. | 1996 | QJM | pmid:8731565 |
| Akeo K et al. | Effects of superoxide dismutase and catalase on growth of retinal pigment epithelial cells in vitro following addition of linoleic acid or linoleic acid hydroperoxide. | 1996 | Ophthalmic Res. | pmid:8726672 |
| Ritskes-Hoitinga J et al. | Effects of two dietary fat levels and four dietary linoleic acid levels on mammary tumor development in Balb/c-MMTV mice under ad libitum feeding conditions. | 1996 | Nutr Cancer | pmid:8710685 |
| Surette ME et al. | Relationship between arachidonate--phospholipid remodeling and apoptosis. | 1996 | Biochemistry | pmid:8703924 |
| Innis SM and Hansen JW | Plasma fatty acid responses, metabolic effects, and safety of microalgal and fungal oils rich in arachidonic and docosahexaenoic acids in healthy adults. | 1996 | Am. J. Clin. Nutr. | pmid:8694015 |
| Carnielli VP et al. | Medium-chain triacylglycerols in formulas for preterm infants: effect on plasma lipids, circulating concentrations of medium-chain fatty acids, and essential fatty acids. | 1996 | Am. J. Clin. Nutr. | pmid:8694014 |
| Rodakiewicz-Nowak J et al. | The effect of linoleic acid on pH inside sodium bis(2-ethylhexyl)sulfosuccinate reverse micelles in isooctane and on the enzymic activity of soybean lipoxygenase. | 1996 | Eur. J. Biochem. | pmid:8681970 |
| Jones GD et al. | Role of lipid hydroperoxides in the activation of 15-lipoxygenase. | 1996 | Biochemistry | pmid:8679548 |
| van Greevenbroek MM et al. | Effects of saturated, mono-, and polyunsaturated fatty acids on the secretion of apo B containing lipoproteins by Caco-2 cells. | 1996 | Atherosclerosis | pmid:8678919 |
| Chen ZY et al. | Accumulation of polyunsaturates is decreased by weight-cycling: whole-body analysis in young, growing rats. | 1996 | Br. J. Nutr. | pmid:8672410 |
| Loftin CD and Eling TE | Prostaglandin synthase 2 expression in epidermal growth factor-dependent proliferation of mouse keratinocytes. | 1996 | Arch. Biochem. Biophys. | pmid:8660674 |
| Süttmann U et al. | Weight gain and increased concentrations of receptor proteins for tumor necrosis factor after patients with symptomatic HIV infection received fortified nutrition support. | 1996 | J Am Diet Assoc | pmid:8655902 |
| Watkins BA et al. | Linoleate impairs collagen synthesis in primary cultures of avian chondrocytes. | 1996 | Proc. Soc. Exp. Biol. Med. | pmid:8650253 |
| Osada K et al. | Dietary protein modifies oxidized cholesterol-induced alterations of linoleic acid and cholesterol metabolism in rats. | 1996 | J. Nutr. | pmid:8648438 |
| Cleland LG et al. | Dietary (n-9) eicosatrienoic acid from a cultured fungus inhibits leukotriene B4 synthesis in rats and the effect is modified by dietary linoleic acid. | 1996 | J. Nutr. | pmid:8648425 |
| Ramasamy S et al. | Oxidized lipid-mediated alterations in proteoglycan metabolism in cultured pulmonary endothelial cells. | 1996 | Atherosclerosis | pmid:8645361 |
| Fischer SM et al. | Arachidonate has protumor-promoting action that is inhibited by linoleate in mouse skin carcinogenesis. | 1996 | J. Nutr. | pmid:8642440 |
| Hussey HJ et al. | Novel anti-tumour activity of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4- benzoquinone (CV-6504) against established murine adenocarcinomas (MAC). | 1996 | Br. J. Cancer | pmid:8630277 |
| Iwase H et al. | Monoepoxide production from linoleic acid by cytochrome c in the presence of cardiolipin. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8630079 |
| De Luca C et al. | Lipoperoxidase activity of Pityrosporum: characterisation of by-products and possible rôle in pityriasis versicolor. | 1996 | Exp. Dermatol. | pmid:8624612 |