Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Circoviridae Infections D018173 2 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Lymphopenia D008231 2 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Lactose Intolerance D007787 2 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Melanosis D008548 4 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Anorexia D000855 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Iwase H et al. Formation of keto and hydroxy compounds of linoleic acid in submitochondrial particles of bovine heart. 1998 Free Radic. Biol. Med. pmid:9641268
Hughes RK et al. Characterization of authentic recombinant pea-seed lipoxygenases with distinct properties and reaction mechanisms. 1998 Biochem. J. pmid:9639559
Battu S et al. Linoleic acid peroxidation by Solanum tuberosum lipoxygenase was activated in the presence of human 5-lipoxygenase-activating protein. 1998 Biochim. Biophys. Acta pmid:9630716
Liu KL and Belury MA Conjugated linoleic acid reduces arachidonic acid content and PGE2 synthesis in murine keratinocytes. 1998 Cancer Lett. pmid:9619853
Ohnishi M et al. Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. 1998 Phytochemistry pmid:9611825
Kikuchi S et al. Modulation of eosinophil chemotactic activities to leukotriene B4 by n-3 polyunsaturated fatty acids. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9610849
Das I and Khan NS Increased arachidonic acid induced platelet chemiluminescence indicates cyclooxygenase overactivity in schizophrenic subjects. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9610837
Kleinfeld AM et al. Transport of long-chain native fatty acids across human erythrocyte ghost membranes. 1998 Biochemistry pmid:9609694
Geetha T et al. Effect of triterpenes from Crataeva nurvala stem bark on lipid peroxidation in adjuvant induced arthritis in rats. 1998 Pharmacol. Res. pmid:9602466
Schaloske R et al. Fatty acids induce release of Ca2+ from acidosomal stores and activate capacitative Ca2+ entry in Dictyostelium discoideum. 1998 Biochem. J. pmid:9601085