| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shin D et al. | Dietary combination effects of conjugated linoleic acid and flaxseed or fish oil on the concentration of linoleic and arachidonic acid in poultry meat. | 2011 | Poult. Sci. | pmid:21597077 |
| Prasad A and PospÃÅ¡il P | Linoleic acid-induced ultra-weak photon emission from Chlamydomonas reinhardtii as a tool for monitoring of lipid peroxidation in the cell membranes. | 2011 | PLoS ONE | pmid:21799835 |
| Arawwawala M et al. | In vitro and in vivo evaluation of antioxidant activity of Trichosanthes cucumerina aerial parts. | 2011 | Acta. Biol. Hung. | pmid:21840826 |
| Lin YH et al. | Altered essential fatty acid metabolism and composition in rat liver, plasma, heart and brain after microalgal DHA addition to the diet. | 2011 | J. Nutr. Biochem. | pmid:21111595 |
| Konkel A and Schunck WH | Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. | 2011 | Biochim. Biophys. Acta | pmid:20869469 |
| Perona JS et al. | Olive oil phenols modulate the triacylglycerol molecular species of human very low-density lipoprotein. A randomized, crossover, controlled trial. | 2011 | Metab. Clin. Exp. | pmid:20934731 |
| McCusker MM and Grant-Kels JM | Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. | 2010 Jul-Aug | Clin. Dermatol. | pmid:20620762 |
| Zovko Koncić M et al. | Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. | 2010 Aug-Sep | Food Chem. Toxicol. | pmid:20488218 |
| Hajlaoui H et al. | Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: a high effectiveness against Vibrio spp. strains. | 2010 Aug-Sep | Food Chem. Toxicol. | pmid:20488223 |
| Maia MR et al. | Toxicity of unsaturated fatty acids to the biohydrogenating ruminal bacterium, Butyrivibrio fibrisolvens. | 2010 | BMC Microbiol. | pmid:20167098 |
| Hirai S et al. | Loss of sense transgene-induced post-transcriptional gene silencing by sequential introduction of the same transgene sequences in tobacco. | 2010 | FEBS J. | pmid:20180844 |
| Thornhill JA et al. | Pathways for the influx of molecules into cercariae of Schistosoma mansoni during skin penetration. | 2010 | Parasitology | pmid:20128942 |
| Dailey MJ et al. | Nutrient specific feeding and endocrine effects of jejunal infusions. | 2010 | Obesity (Silver Spring) | pmid:20134410 |
| Combet E et al. | Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20112267 |
| Castellanos P et al. | Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. | 2010 | Reprod. Toxicol. | pmid:20096347 |
| Coyral-Castel S et al. | Effects of unsaturated fatty acids on progesterone secretion and selected protein kinases in goat granulosa cells. | 2010 | Domest. Anim. Endocrinol. | pmid:20097509 |
| Nakamura T et al. | Excessive fat restriction might promote the recurrence of colorectal tumors. | 2010 | Nutr Cancer | pmid:20099189 |
| Beevi SS et al. | Polyphenolics profile, antioxidant and radical scavenging activity of leaves and stem of Raphanus sativus L. | 2010 | Plant Foods Hum Nutr | pmid:20072818 |
| Privé F et al. | Temperature and duration of heating of sunflower oil affect ruminal biohydrogenation of linoleic acid in vitro. | 2010 | J. Dairy Sci. | pmid:20105542 |
| RodrÃguez AM et al. | Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells. | 2010 | Cell. Physiol. Biochem. | pmid:20110694 |
| Ivanova L et al. | Phomenins and fatty acids from Alternaria infectoria. | 2010 | Toxicon | pmid:20060014 |
| Won JC et al. | Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity. | 2010 | Arterioscler. Thromb. Vasc. Biol. | pmid:19965780 |
| Dimri M et al. | Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells. | 2010 | Carcinogenesis | pmid:19969553 |
| Olveira G et al. | Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. | 2010 | Arch. Bronconeumol. | pmid:20045240 |
| Li Y et al. | Bone mineral content is positively correlated to n-3 fatty acids in the femur of growing rats. | 2010 | Br. J. Nutr. | pmid:20420751 |
| Kubala L et al. | Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. | 2010 | Free Radic. Biol. Med. | pmid:20156554 |
| Bradbury KE et al. | The serum fatty acids myristic acid and linoleic acid are better predictors of serum cholesterol concentrations when measured as molecular percentages rather than as absolute concentrations. | 2010 | Am. J. Clin. Nutr. | pmid:19955401 |
| Gholivand MB et al. | Chemical composition and antioxidant activities of the essential oil and methanol extracts of Psammogeton canescens. | 2010 | Food Chem. Toxicol. | pmid:19748545 |
| Alvaro A et al. | Polyunsaturated fatty acids down-regulate in vitro expression of the key intestinal cholesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids. | 2010 | J. Nutr. Biochem. | pmid:19443194 |
| Walloschke B et al. | Enrichment of RAW264.7 macrophages with essential 18-carbon fatty acids affects both respiratory burst and production of immune modulating cytokines. | 2010 | J. Nutr. Biochem. | pmid:19447017 |
| Huang CB et al. | Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. | 2010 | Arch. Oral Biol. | pmid:20541177 |
| Rodrigues HG et al. | Dietary free oleic and linoleic acid enhances neutrophil function and modulates the inflammatory response in rats. | 2010 | Lipids | pmid:20730605 |
| Tel G et al. | Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities. | 2010 | Food Chem. Toxicol. | pmid:20732375 |
| Aziz AA et al. | Increasing Dietary alpha-linolenic acid enhances tissue levels of long-chain n-3 PUFA when linoleic acid intake is low in hamsters. | 2010 | Ann. Nutr. Metab. | pmid:20714137 |
| Gutiérrez-Correa J | Trypanosoma cruzi dihydrolipoamide dehydrogenase as target of reactive metabolites generated by cytochrome c/hydrogen peroxide (or linoleic acid hydroperoxide)/phenol systems. | 2010 | Free Radic. Res. | pmid:20815787 |
| Serhan Z et al. | Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases. | 2010 | Chem. Commun. (Camb.) | pmid:20721385 |
| Bolton B and Halpern BP | Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. | 2010 | Chem. Senses | pmid:20100787 |
| Gotoh N et al. | Highly unsaturated fatty acid might act as an antioxidant in emulsion system oxidized by azo compound. | 2010 | J Oleo Sci | pmid:21099140 |
| Wu TC et al. | Fatty acid composition of Taiwanese human milk. | 2010 | J Chin Med Assoc | pmid:21093826 |
| West SG et al. | Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial function. | 2010 | J Am Coll Nutr | pmid:21677123 |
| Tremblay-Mercier J et al. | Bezafibrate mildly stimulates ketogenesis and fatty acid metabolism in hypertriglyceridemic subjects. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20404010 |
| Liu S and Han B | Differential expression pattern of an acidic 9/13-lipoxygenase in flower opening and senescence and in leaf response to phloem feeders in the tea plant. | 2010 | BMC Plant Biol. | pmid:20969806 |
| Benammar C et al. | Zizyphus lotus L. (Desf.) modulates antioxidant activity and human T-cell proliferation. | 2010 | BMC Complement Altern Med | pmid:20868496 |
| Lu X et al. | Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction. | 2010 | Lipids Health Dis | pmid:20868498 |
| Khiaosa-Ard R et al. | Transfer of linoleic and linolenic acid from feed to milk in cows fed isoenergetic diets differing in proportion and origin of concentrates and roughages. | 2010 | J. Dairy Res. | pmid:20482940 |
| Sahoo PK and Behera P | Synthesis and biological screening of some novel amidocarbamate derivatives of ketoprofen. | 2010 | Eur J Med Chem | pmid:20434240 |
| Campoy C et al. | [Update of knowledge, recommendations and full consensus about the role of long chain polyunsaturated fatty acids in pregnancy, lactating period and first year of life.Asociación Española de PediatrÃa. Sociedad Española de GinecologÃa y Obstetricia. Sociedad Española de Nutrición Comunitaria. Academia Española deNutrición y Ciencias de la Alimentación]. | 2010 | Med Clin (Barc) | pmid:20434734 |
| Goicoechea E and Guillen MD | Analysis of hydroperoxides, aldehydes and epoxides by 1H nuclear magnetic resonance in sunflower oil oxidized at 70 and 100 degrees C. | 2010 | J. Agric. Food Chem. | pmid:20438132 |
| Cannata S et al. | Effect of visual marbling on sensory properties and quality traits of pork loin. | 2010 | Meat Sci. | pmid:20416803 |
| Macouzet M et al. | Genetic and functional aspects of linoleate isomerase in Lactobacillus acidophilus. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20461509 |