| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Anorexia | D000855 | 8 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Colitis | D003092 | 69 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kozachenko AI et al. | Characteristics of beta-carotene-induced inhibition of free radical oxidation of fatty acids with different degree of unsaturation. | 2001 Jul-Aug | Dokl. Biochem. Biophys. | pmid:11665681 |
| Kolesnichenko AV et al. | Influence of CSP 310 and CSP 310-like proteins from cereals on mitochondrial energetic activity and lipid peroxidation in vitro and in vivo. | 2001 | BMC Plant Biol. | pmid:11667950 |
| Rahamatalla AB et al. | Changes in fatty acids composition during seed growth and physicochemical characteristics of oil extracted from four safflower cultivars. | 2001 | Plant Foods Hum Nutr | pmid:11678443 |
| Djoussé L et al. | Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study. | 2001 | Am. J. Clin. Nutr. | pmid:11684529 |
| López Bote CJ et al. | Effect of dietary linoleic acid concentration and vitamin E supplementation on cell desquamation and susceptibility to oxidative damage of pig jejunal mucosa. | 2001 | J Anim Physiol Anim Nutr (Berl) | pmid:11686769 |
| Aleynik MK and Lieber CS | Dilinoleoylphosphatidylcholine decreases ethanol-induced cytochrome P4502E1. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11689017 |
| Finley JW and Davis CD | Manganese absorption and retention in rats is affected by the type of dietary fat. | 2001 | Biol Trace Elem Res | pmid:11697763 |
| Kelavkar UP et al. | Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. | 2001 | Carcinogenesis | pmid:11698337 |
| Ramaswamy N et al. | Composition and flavor of milk and butter from cows fed fish oil, extruded soybeans, or their combination. | 2001 | J. Dairy Sci. | pmid:11699444 |
| Hagenlocher T et al. | Influence of dietary fatty acid, vegetable, and vitamin intake on etheno-DNA adducts in white blood cells of healthy female volunteers: a pilot study. | 2001 | Cancer Epidemiol. Biomarkers Prev. | pmid:11700267 |
| O'Quinn PR et al. | Conjugated linoleic acid. | 2000 | Anim Health Res Rev | pmid:11706843 |
| Cigliano L et al. | Estradiol esterification in the human preovulatory follicle. | 2001 | Steroids | pmid:11711117 |
| Strandvik B et al. | Essential fatty acid deficiency in relation to genotype in patients with cystic fibrosis. | 2001 | J. Pediatr. | pmid:11713441 |
| Moran JH et al. | Linoleic acid prevents chloride influx and cellular lysis in rabbit renal proximal tubules exposed to mitochondrial toxicants. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11714247 |
| Calaf RE et al. | Automated strong cation exchange extraction of fatty acid esters of 3-(N-phenylamino)-1,2-propanediol from oil samples for routine quantification by HPLC-APCI/MS/MS. | 2001 | J. Agric. Food Chem. | pmid:11714286 |
| Palinski W et al. | Maternal hypercholesterolemia and treatment during pregnancy influence the long-term progression of atherosclerosis in offspring of rabbits. | 2001 | Circ. Res. | pmid:11717155 |
| Milani G et al. | Respiratory chain network in mitochondria of Candida parapsilosis: ADP/O appraisal of the multiple electron pathways. | 2001 | FEBS Lett. | pmid:11718721 |
| Weber TE et al. | Evaluation of conjugated linoleic acid and dietary antibiotics as growth promotants in weanling pigs. | 2001 | J. Anim. Sci. | pmid:11721832 |
| Thom E et al. | Conjugated linoleic acid reduces body fat in healthy exercising humans. | 2001 Sep-Oct | J. Int. Med. Res. | pmid:11725826 |
| Glew RH et al. | Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728165 |
| Villalpando S et al. | [13C]linoleic acid oxidation and transfer into milk in stunted lactating women with contrasting body mass indexes. | 2001 | Am. J. Clin. Nutr. | pmid:11729835 |
| Park Y and Pariza MW | The effects of dietary conjugated nonadecadienoic acid on body composition in mice. | 2001 | Biochim. Biophys. Acta | pmid:11731328 |
| Peters JM et al. | Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice. | 2001 | Biochim. Biophys. Acta | pmid:11731333 |
| Lee BD et al. | Nutritive and economic values of high oil corn in layer diet. | 2001 | Poult. Sci. | pmid:11732667 |
| Watanabe T et al. | Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase. | 2001 | Eur. J. Biochem. | pmid:11733005 |
| Gustafsson MC et al. | Fatty-acid-displaced transcriptional repressor, a conserved regulator of cytochrome P450 102 transcription in Bacillus species. | 2001 | Arch. Microbiol. | pmid:11734890 |
| Pelikánová T et al. | Serum phospholipid fatty acid composition and insulin action in type 2 diabetic patients. | 2001 | Metab. Clin. Exp. | pmid:11735096 |
| Fernández-Real JM et al. | Circulating granulocyte-macrophage colony-stimulating factor and serum fatty acid composition in men and women. | 2001 | Metab. Clin. Exp. | pmid:11735097 |
| Büyükokuroğlu ME et al. | In vitro antioxidant properties of dantrolene sodium. | 2001 | Pharmacol. Res. | pmid:11735355 |
| Melamed-Frank M et al. | Structure-function analysis of the antioxidant properties of haptoglobin. | 2001 | Blood | pmid:11739174 |
| Coles B et al. | Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP. | 2002 | J. Biol. Chem. | pmid:11748216 |
| Pirtle IL et al. | Molecular cloning and functional expression of the gene for a cotton Delta-12 fatty acid desaturase (FAD2). | 2001 | Biochim. Biophys. Acta | pmid:11750064 |
| Smith WG et al. | Lipoprotein susceptibility to oxidation in the macromolecular fraction of plasma: relation to plasma lipids and oleate/linoleate ratio in comparison with whole plasma in hypertriglyceridemia. | 2002 | Clin. Chim. Acta | pmid:11750269 |
| Smith WG et al. | Simple and rapid assessment of lipoprotein susceptibility to oxidation in the macromolecule fraction of plasma. | 2002 | Clin. Chim. Acta | pmid:11750270 |
| Park Y and Pariza MW | Lipoxygenase inhibitors inhibit heparin-releasable lipoprotein lipase activity in 3T3-L1 adipocytes and enhance body fat reduction in mice by conjugated linoleic acid. | 2001 | Biochim. Biophys. Acta | pmid:11750884 |
| Larqué E et al. | Dietary trans fatty acids in early life: a review. | 2001 | Early Hum. Dev. | pmid:11755033 |
| Mottaran E et al. | Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease. | 2002 | Free Radic. Biol. Med. | pmid:11755315 |
| Ohnuki K et al. | Increased energy metabolism and suppressed body fat accumulation in mice by a low concentration of conjugated linoleic acid. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11758910 |
| Ip C et al. | Control of rat mammary epithelium proliferation by conjugated linoleic acid. | 2001 | Nutr Cancer | pmid:11759286 |
| Yang H et al. | Modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutation in the cecum and colon of big blue rats by conjugated linoleic acid and 1,2-dithiole-3-thione. | 2001 | Nutr Cancer | pmid:11759290 |
| Radschuweit A et al. | Capillary zone electrophoresis with electrochemical detection--a simple and effective method to analyze oxygen-consuming and peroxide-forming processes. | 2001 | J Chromatogr A | pmid:11765078 |
| Eggert JM et al. | Effects of conjugated linoleic acid on the belly firmness and fatty acid composition of genetically lean pigs. | 2001 | J. Anim. Sci. | pmid:11768116 |
| Olson RE | The key to an enigma: how do dietary polyunsaturated fatty acids lower serum cholesterol? | 2002 | J. Nutr. | pmid:11773520 |
| Tripathi AK et al. | A physiochemical mechanism of hemozoin (beta-hematin) synthesis by malaria parasite. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11779214 |
| Birnbaum L | Addition of conjugated linoleic acid to a herbal anticellulite pill. | 2001 Sep-Oct | Adv Ther | pmid:11783459 |
| De Vriese SR et al. | Estimation of dietary fat intake of Belgian pregnant women. Comparison of two methods. | 2001 | Ann. Nutr. Metab. | pmid:11786650 |
| Gwak HS and Chun IK | Effect of vehicles and enhancers on the in vitro skin penetration of aspalatone and its enzymatic degradation across rat skins. | 2001 | Arch. Pharm. Res. | pmid:11794538 |
| Vargas F et al. | In vitro antioxidant and photo-oxidant properties of dipyridamole. | 2001 Nov-Dec | Int. J. Toxicol. | pmid:11797818 |
| Kawajiri H et al. | Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activity. | 2002 | Arch. Biochem. Biophys. | pmid:11811948 |
| Mitchell LA et al. | Linoleic acid, cis-epoxyoctadecenoic acids, and dihydroxyoctadecadienoic acids are toxic to Sf-21 cells in the absence of albumin. | 2002 | Toxicol. Lett. | pmid:11814707 |