Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

MeSH term MeSH ID Detail
Acute Coronary Syndrome D054058 11 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Atherosclerosis D050197 85 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Restenosis D023903 10 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Circoviridae Infections D018173 2 associated lipids
Glucose Intolerance D018149 13 associated lipids
Community-Acquired Infections D017714 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

Download all related citations
Per page 10 20 50 100 | Total 4513
Authors Title Published Journal PubMed Link
Azain MJ et al. Dietary conjugated linoleic acid reduces rat adipose tissue cell size rather than cell number. 2000 J. Nutr. pmid:10827208
Tokumura A et al. Structural identification of phosphatidylcholines having an oxidatively shortened linoleate residue generated through its oxygenation with soybean or rabbit reticulocyte lipoxygenase. 2000 J. Lipid Res. pmid:10828088
Bloodsworth A et al. Manganese-porphyrin reactions with lipids and lipoproteins. 2000 Free Radic. Biol. Med. pmid:10832063
Maccarrone M et al. Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. 2000 Biochem. Biophys. Res. Commun. pmid:10833416
McHowat J and Creer MH Selective plasmalogen substrate utilization by thrombin-stimulated Ca(2+)-independent PLA(2) in cardiomyocytes. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10843891
Richieri GV et al. Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. 2000 Biochemistry pmid:10852718
Smith JC et al. Orosensory factors in the ingestion of corn oil/sucrose mixtures by the rat. 2000 Apr 1-15 Physiol. Behav. pmid:10854925
Williams JP et al. The role of phosphatidylcholine in fatty acid exchange and desaturation in Brassica napus L. leaves. 2000 Biochem. J. pmid:10861220
Yoshiki Y et al. Chemiluminescence and reactive oxygen scavenging activities of the hydrogen peroxide/gallic acid/lactoperoxidase system. 2000 May-Jun Luminescence pmid:10862147
Watanabe T et al. Formation of acyl radical in lipid peroxidation of linoleic acid by manganese-dependent peroxidase from Ceriporiopsis subvermispora and Bjerkandera adusta. 2000 Eur. J. Biochem. pmid:10866827
Decsi T and Koletzko B Effects of protein-energy malnutrition and human immunodeficiency virus-1 infection on essential fatty acid metabolism in children. 2000 Nutrition pmid:10869902
Latour MA et al. Effects of conjugated linoleic acid. 1. Fatty acid modification of yolks and neonatal fatty acid metabolism. 2000 Poult. Sci. pmid:10875761
Latour MA et al. Effects of conjugated linoleic acid. 2. Embryonic and neonatal growth and circulating lipids. 2000 Poult. Sci. pmid:10875762
Kumar KV et al. Oxidant stress and essential fatty acids in patients with risk and established ARDS. 2000 Clin. Chim. Acta pmid:10876008
Loreau O et al. Large-scale preparation of (9Z,12E)-[1-(13)C]-octadeca-9,12-dienoic acid, (9Z,12Z,15E)-[1-(13)C]-octadeca-9,12,15-trienoic acid and their [1-(13)C] all-cis isomers. 2000 Chem. Phys. Lipids pmid:10878236
Lesage F et al. Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors. 2000 J. Biol. Chem. pmid:10880510
Gonzalez B et al. Metabolism of n -9, n -6 and n -3 fatty acids in hepatoma Morris 7777 cells. Preferential accumulation of linoleic acid in cardiolipin. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883061
Tominaga K et al. Effect of lipid polarization by centrifugation at different developmental stages on post-thaw survival of bovine in vitro produced 16-cell embryos. 2000 Theriogenology pmid:10883852
Moussa M et al. Relationship between the fatty acid composition of rat lymphocytes and immune functions. 2000 Br. J. Nutr. pmid:10884721
Freiberger CE et al. Nutrient content of the edible leaves of seven wild plants from Niger. 1998 Plant Foods Hum Nutr pmid:10890758