| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
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|---|---|---|---|---|
| Kim SY et al. | S-adenosyl methionine prevents endothelial dysfunction by inducing heme oxygenase-1 in vascular endothelial cells. | 2013 | Mol. Cells | pmid:24046187 |
| Ivan M et al. | Rumen fermentation and microbial population in lactating dairy cows receiving diets containing oilseeds rich in C-18 fatty acids. | 2013 | Br. J. Nutr. | pmid:22850225 |
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| McGowan MM et al. | A proof of principle clinical trial to determine whether conjugated linoleic acid modulates the lipogenic pathway in human breast cancer tissue. | 2013 | Breast Cancer Res. Treat. | pmid:23417336 |
| Mabalirajan U et al. | Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. | 2013 | Sci Rep | pmid:23443229 |
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| Emery JA et al. | Δ-6 Desaturase substrate competition: dietary linoleic acid (18:2n-6) has only trivial effects on α-linolenic acid (18:3n-3) bioconversion in the teleost rainbow trout. | 2013 | PLoS ONE | pmid:23460861 |
| SuardÃaz R et al. | An insight into the regiospecificity of linoleic acid peroxidation catalyzed by mammalian 15-lipoxygenases. | 2013 | J Phys Chem B | pmid:23496802 |
| Cardoso S et al. | UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats. | 2013 | J. Bioenerg. Biomembr. | pmid:23504111 |
| Stamey Lanier J et al. | Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. | 2013 | Lipids | pmid:23504269 |
| Saubeau G et al. | Differential induction of oxylipin pathway in potato and tobacco cells by bacterial and oomycete elicitors. | 2013 | Plant Cell Rep. | pmid:23479199 |
| Godinot N et al. | Activation of tongue-expressed GPR40 and GPR120 by non caloric agonists is not sufficient to drive preference in mice. | 2013 | Neuroscience | pmid:23831422 |
| Cao AH et al. | Composition of long chain polyunsaturated fatty acids (LC-PUFAs) in different encephalic regions and its association with behavior in spontaneous hypertensive rat (SHR). | 2013 | Brain Res. | pmid:23811335 |
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| Kälber T et al. | Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows. | 2013 | J. Dairy Res. | pmid:23253429 |
| Gage SH et al. | Functionalization of monodisperse iron oxide NPs and their properties as magnetically recoverable catalysts. | 2013 | Langmuir | pmid:23234434 |
| Li A et al. | Thermally induced isomerization of linoleic acid in soybean oil. | 2013 | Chem. Phys. Lipids | pmid:23261796 |
| Zamora-Rojas E et al. | Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. | 2013 | Meat Sci. | pmid:23793086 |
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| Gousiadou C et al. | Minor iridoids from Scutellaria albida ssp. albida. Inhibitory potencies on lipoxygenase, linoleic acid lipid peroxidation and antioxidant activity of iridoids from Scutellaria sp. | 2013 | J Enzyme Inhib Med Chem | pmid:22630074 |
| McPherson PA et al. | Mechanism for the enhanced peroxidation of linoleic acid by a titanium dioxide/hypochlorite system. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23178466 |
| Serna-Marquez N et al. | Role of LOXs and COX-2 on FAK activation and cell migration induced by linoleic acid in MDA-MB-231 breast cancer cells. | 2013 | Cell Oncol (Dordr) | pmid:23179791 |
| Gámez-Meza N et al. | Chemical characterisation of kernels, kernel meals and oils from Jatropha cordata and Jatropha cardiophylla seeds. | 2013 | J. Sci. Food Agric. | pmid:23180465 |
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| Bakır T et al. | Polar paradox revisited: analogous pairs of hydrophilic and lipophilic antioxidants in linoleic acid emulsion containing Cu(II). | 2013 | J. Sci. Food Agric. | pmid:23520052 |
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| Fujii M et al. | Deficiency of n-6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis-like pruritic skin inflammation in special diet-fed hairless mice. | 2013 | Exp. Dermatol. | pmid:23528213 |
| Men XM et al. | Age-related changes and nutritional regulation of myosin heavy-chain composition in longissimus dorsi of commercial pigs. | 2013 | Animal | pmid:23764195 |
| Al-Bishri WM | Favorable effects of flaxseed supplemented diet on liver and kidney functions in hypertensive Wistar rats. | 2013 | J Oleo Sci | pmid:24005015 |
| Daud AZ et al. | The trans fatty acid content in human milk and its association with maternal diet among lactating mothers in Malaysia. | 2013 | Asia Pac J Clin Nutr | pmid:23945414 |
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| Gibson RA et al. | Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22515943 |
| Steffen BT et al. | n-3 and n-6 Fatty acids are independently associated with lipoprotein-associated phospholipase A2 in the Multi-Ethnic Study of Atherosclerosis. | 2013 | Br. J. Nutr. | pmid:23551952 |
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| Okada Y et al. | Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T helper 17 cell polarization. | 2013 | Clin. Exp. Immunol. | pmid:24028683 |
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| Peters BD et al. | Polyunsaturated fatty acid concentration predicts myelin integrity in early-phase psychosis. | 2013 | Schizophr Bull | pmid:22927668 |