Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Liu Y and Roth JP | A Revised Mechanism for Human Cyclooxygenase-2. | 2016 | J. Biol. Chem. | pmid:26565028 |
Jory J | Abnormal fatty acids in Canadian children with autism. | 2016 | Nutrition | pmid:26746679 |
McNamara RK and Welge JA | Meta-analysis of erythrocyte polyunsaturated fatty acid biostatus in bipolar disorder. | 2016 | Bipolar Disord | pmid:27087497 |
Ramsden CE et al. | Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73). | 2016 | BMJ | pmid:27071971 |
Rondanelli M et al. | Effects of two-months balanced diet in metabolically healthy obesity: lipid correlations with gender and BMI-related differences. | 2015 | Lipids Health Dis | pmid:26511930 |
Dahlhoff M et al. | EGFR/ERBB receptors differentially modulate sebaceous lipogenesis. | 2015 | FEBS Lett. | pmid:25889637 |
Gouveia-Figueira S et al. | Serum levels of oxylipins in achilles tendinopathy: an exploratory study. | 2015 | PLoS ONE | pmid:25875933 |
Mansour AB et al. | Effect of agricultural sites on differentiation between Chemlali and Neb Jmel olive oils. | 2015 | J Oleo Sci | pmid:25833451 |
Kim SY et al. | Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway. | 2015 | Int. J. Mol. Med. | pmid:25672876 |
Nakahashi H et al. | Evaluation of the Key Odorants in Volatile Oils from Tubers of Apios americana Medikus. | 2015 | J Oleo Sci | pmid:26521814 |