Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sánchez-Vioque R et al. | Interaction of chickpea (Cicer arietinum L.) legumin with oxidized linoleic acid. | 1999 | J. Agric. Food Chem. | pmid:10552371 |
| Domingo N et al. | Effects of dexamethasone and linoleic acid on hepatic secretion of biliary lipids and anionic polypeptide factor: In vivo and in vitro studies. | 1999 Nov-Dec | Digestion | pmid:10545720 |
| Kulkarni AP and Sajan M | Lipoxygenase-another pathway for glutathione conjugation of xenobiotics: A study with human term placental lipoxygenase and ethacrynic acid. | 1999 | Arch. Biochem. Biophys. | pmid:10545208 |
| Murphy J et al. | Fat malabsorption in cystic fibrosis patients. | 1999 | Am. J. Clin. Nutr. | pmid:10539762 |
| Rose DP and Connolly JM | Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice. | 1999 | Int. J. Oncol. | pmid:10536186 |
| Dhiman TR et al. | Conjugated linoleic acid content of milk from cows fed different diets. | 1999 | J. Dairy Sci. | pmid:10531600 |
| Howard FA and Henderson C | Hydrogenation of polyunsaturated fatty acids by human colonic bacteria. | 1999 | Lett. Appl. Microbiol. | pmid:10530040 |
| Filley SJ et al. | Prostaglandin f(2alpha) concentrations, fatty acid profiles, and fertility in lipid-infused postpartum beef heifers. | 1999 | Biol. Reprod. | pmid:10529280 |
| Dauchy RT et al. | Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism. | 1999 | Cancer Lett. | pmid:10529012 |
| Minich DM et al. | Biliary phospholipid secretion is not required for intestinal absorption and plasma status of linoleic acid in mice. | 1999 | Biochim. Biophys. Acta | pmid:10526224 |
| Arutselvan N et al. | Antioxidative activity of 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid. | 1999 | Arzneimittelforschung | pmid:10514898 |
| Xu M and Dashwood RH | Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis. | 1999 | Cancer Lett. | pmid:10503900 |
| Masella R et al. | Antioxidant activity of 3,4-DHPEA-EA and protocatechuic acid: a comparative assessment with other olive oil biophenols. | 1999 | Redox Rep. | pmid:10496414 |
| Tamatani T et al. | Neoplastic conversion of human urothelial cells in vitro by overexpression of H2O2-generating peroxisomal fatty acyl CoA oxidase. | 1999 | Int. J. Oncol. | pmid:10493957 |
| Rickert KW and Klinman JP | Nature of hydrogen transfer in soybean lipoxygenase 1: separation of primary and secondary isotope effects. | 1999 | Biochemistry | pmid:10493789 |
| Blask DE et al. | Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. | 1999 | Cancer Res. | pmid:10493527 |
| Sauer LA et al. | 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo. | 1999 | Cancer Res. | pmid:10493526 |
| Precht D and Molkentin J | C18:1, C18:2 and C18:3 trans and cis fatty acid isomers including conjugated cis delta 9, trans delta 11 linoleic acid (CLA) as well as total fat composition of German human milk lipids. | 1999 | Nahrung | pmid:10481820 |
| Kankaanpää P et al. | Dietary fatty acids and allergy. | 1999 | Ann. Med. | pmid:10480759 |
| Lin MY and Yen CL | Reactive oxygen species and lipid peroxidation product-scavenging ability of yogurt organisms. | 1999 | J. Dairy Sci. | pmid:10480088 |