Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Nosaka S and Miyazawa M | Characterization of volatile components and odor-active compounds in the oil of edible mushroom Boletopsis leucomelas. | 2014 | J Oleo Sci | pmid:24881770 |
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Saito H and Ishikawa S | Lipid classes and fatty acid profile of cultured and wild black rockfish, Sebastes schlegeli. | 2014 | J Oleo Sci | pmid:24829130 |
Morris JB et al. | Flavonol content, oil%, and fatty acid composition variability in seeds of Teramnus labialis and T. uncinatus accessions with nutraceutical potential. | 2014 | J Diet Suppl | pmid:25054688 |
Verlotta A and Trono D | Expression, purification and refolding of active durum wheat (Triticum durum Desf.) secretory phospholipase A2 from inclusion bodies of Escherichia coli. | 2014 | Protein Expr. Purif. | pmid:24925645 |
Yang B et al. | Synthesis of conjugated linoleic acid by the linoleate isomerase complex in food-derived lactobacilli. | 2014 | J. Appl. Microbiol. | pmid:24750362 |
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Rodriguez MA et al. | Concordance analysis between estimation methods of milk fatty acid content. | 2014 | Food Chem | pmid:24629954 |
Spartano NL et al. | Linoleic acid suppresses cholesterol efflux and ATP-binding cassette transporters in murine bone marrow-derived macrophages. | 2014 | Lipids | pmid:24595513 |
Scalerandi MV et al. | Effect of conjugated linoleic acid mixtures and different edible oils in body composition and lipid regulation in mice. | 2014 | Nutr Hosp | pmid:24559004 |
Asselin C et al. | Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure. | 2014 | Redox Biol | pmid:24494189 |
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Guo HH et al. | XsFAD2 gene encodes the enzyme responsible for the high linoleic acid content in oil accumulated in Xanthoceras sorbifolia seeds. | 2014 | J. Sci. Food Agric. | pmid:23775588 |
Huang X et al. | Serum fatty acid patterns, insulin sensitivity and the metabolic syndrome in individuals with chronic kidney disease. | 2014 | J. Intern. Med. | pmid:24011327 |
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Garrel G et al. | Unsaturated fatty acids disrupt Smad signaling in gonadotrope cells leading to inhibition of FSHβ gene expression. | 2014 | Endocrinology | pmid:24248462 |
Kim JY et al. | Role of moisture on the lipid oxidation determined by D(2)O in a linoleic acid model system. | 2014 | Food Chem | pmid:24176324 |
Usami A et al. | Characteristic odorants from bailingu oyster mushroom (Pleurotus eryngii var. tuoliensis) and summer oyster mushroom (Pleurotus cystidiosus). | 2014 | J Oleo Sci | pmid:24919476 |
Sponton OE et al. | Effect of limited enzymatic hydrolysis on linoleic acid binding properties of β-lactoglobulin. | 2014 | Food Chem | pmid:24176383 |
Dal Bosco A et al. | Effect of dietary alfalfa on the fatty acid composition and indexes of lipid metabolism of rabbit meat. | 2014 | Meat Sci. | pmid:24036258 |
Alvheim AR et al. | Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet. | 2014 | Lipids | pmid:24081493 |
Su MH et al. | Chemical composition of seed oils in native Taiwanese Camellia species. | 2014 | Food Chem | pmid:24629982 |
López-Cervantes J et al. | Effect of solvents and methods of stirring in extraction of lycopene, oleoresin and fatty acids from over-ripe tomato. | 2014 | Int J Food Sci Nutr | pmid:24111501 |
Bakır T et al. | Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2. | 2014 | Int J Food Sci Nutr | pmid:24152374 |
Yavin E et al. | Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency. | 2014 | Biochim. Biophys. Acta | pmid:24960100 |
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López A et al. | Compressive mechanical properties and cytocompatibility of bone-compliant, linoleic acid-modified bone cement in a bovine model. | 2014 | J Mech Behav Biomed Mater | pmid:24508711 |
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Li KC et al. | [A preliminary study of the inhibitive efficacy of iodized linoleic acid and its fluorodeoxyuridine ester in hepatocellular cancer]. | 2013 | Zhonghua Gan Zang Bing Za Zhi | pmid:24025140 |
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