Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Masella R et al. | Antioxidant activity of 3,4-DHPEA-EA and protocatechuic acid: a comparative assessment with other olive oil biophenols. | 1999 | Redox Rep. | pmid:10496414 |
Xu M and Dashwood RH | Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis. | 1999 | Cancer Lett. | pmid:10503900 |
Arutselvan N et al. | Antioxidative activity of 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid. | 1999 | Arzneimittelforschung | pmid:10514898 |
Minich DM et al. | Biliary phospholipid secretion is not required for intestinal absorption and plasma status of linoleic acid in mice. | 1999 | Biochim. Biophys. Acta | pmid:10526224 |
Dauchy RT et al. | Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism. | 1999 | Cancer Lett. | pmid:10529012 |
Filley SJ et al. | Prostaglandin f(2alpha) concentrations, fatty acid profiles, and fertility in lipid-infused postpartum beef heifers. | 1999 | Biol. Reprod. | pmid:10529280 |
Howard FA and Henderson C | Hydrogenation of polyunsaturated fatty acids by human colonic bacteria. | 1999 | Lett. Appl. Microbiol. | pmid:10530040 |
Dhiman TR et al. | Conjugated linoleic acid content of milk from cows fed different diets. | 1999 | J. Dairy Sci. | pmid:10531600 |
Rose DP and Connolly JM | Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice. | 1999 | Int. J. Oncol. | pmid:10536186 |
Murphy J et al. | Fat malabsorption in cystic fibrosis patients. | 1999 | Am. J. Clin. Nutr. | pmid:10539762 |