Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Cogo PE et al. | Endogenous surfactant metabolism in critically ill infants measured with stable isotope labeled fatty acids. | 1999 | Pediatr. Res. | pmid:10022597 |
Umezawa M et al. | High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice. | 1999 | J. Nutr. | pmid:10024623 |
Cunnane SC | The long history of essential fatty acids but belated knowledge about linoleate deficiency per se: a paradox. | 1999 | J. Nutr. | pmid:10024625 |
Aki T et al. | Molecular cloning and functional characterization of rat delta-6 fatty acid desaturase. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10049752 |
Avery SV et al. | Stimulation of strontium accumulation in linoleate-enriched Saccharomyces cerevisiae is a result of reduced Sr2+ efflux. | 1999 | Appl. Environ. Microbiol. | pmid:10049882 |
Josyula S et al. | Inhibition of DNA adduct formation of PhIP in female F344 rats by dietary conjugated linoleic acid. | 1998 | Nutr Cancer | pmid:10050262 |
Josyula S and Schut HA | Effects of dietary conjugated linoleic acid on DNA adduct formation of PhIP and IQ after bolus administration to female F344 rats. | 1998 | Nutr Cancer | pmid:10050263 |
Jussila M et al. | Separation of linoleic acid oxidation products by micellar electrokinetic capillary chromatography and nonaqueous capillary electrophoresis. | 1999 | Electrophoresis | pmid:10065966 |
Rukkwamsuk T et al. | Hepatic fatty acid composition in periparturient dairy cows with fatty liver induced by intake of a high energy diet in the dry period. | 1999 | J. Dairy Sci. | pmid:10068949 |