Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kulkarni AP and Sajan M | Lipoxygenase-another pathway for glutathione conjugation of xenobiotics: A study with human term placental lipoxygenase and ethacrynic acid. | 1999 | Arch. Biochem. Biophys. | pmid:10545208 |
Domingo N et al. | Effects of dexamethasone and linoleic acid on hepatic secretion of biliary lipids and anionic polypeptide factor: In vivo and in vitro studies. | 1999 Nov-Dec | Digestion | pmid:10545720 |
Sánchez-Vioque R et al. | Interaction of chickpea (Cicer arietinum L.) legumin with oxidized linoleic acid. | 1999 | J. Agric. Food Chem. | pmid:10552371 |
Angerosa F et al. | Virgin olive oil volatile compounds from lipoxygenase pathway and characterization of some italian cultivars. | 1999 | J. Agric. Food Chem. | pmid:10552376 |
Budi Santosa FX and Padua GW | Tensile properties and water absorption of zein sheets plasticized with oleic and linoleic acids. | 1999 | J. Agric. Food Chem. | pmid:10552498 |
Henderson DE et al. | Quantitative HPLC determination of the antioxidant activity of capsaicin on the formation of lipid hydroperoxides of linoleic acid: a comparative study against BHT and melatonin. | 1999 | J. Agric. Food Chem. | pmid:10552527 |
Kuo JM et al. | Rapid photometric assay evaluating antioxidative activity in edible plant material. | 1999 | J. Agric. Food Chem. | pmid:10552632 |
Grobas S et al. | Laying hen productivity as affected by energy, supplemental fat, and linoleic acid concentration of the diet. | 1999 | Poult. Sci. | pmid:10560827 |
Du M et al. | Effect of dietary conjugated linoleic acid on the composition of egg yolk lipids. | 1999 | Poult. Sci. | pmid:10560841 |
López-Nicolás JM et al. | Rapid reversed-phase high-performance liquid chromatographic determination of the regiospecificity of lipoxygenase products on linoleic acid. | 1999 | J Chromatogr A | pmid:10563421 |