Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Park HG et al. | Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 ɑ-linolenic acids for FADS2 mediated Δ6-desaturation. | 2016 | Biochim. Biophys. Acta | pmid:26597785 |
Sergeant S et al. | Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. | 2016 | Br. J. Nutr. | pmid:26615716 |
Mojumdar EH et al. | Stratum corneum lipid matrix: Location of acyl ceramide and cholesterol in the unit cell of the long periodicity phase. | 2016 | Biochim. Biophys. Acta | pmid:27169629 |
Liu G et al. | Biotype Characterization, Developmental Profiling, Insecticide Response and Binding Property of Bemisia tabaci Chemosensory Proteins: Role of CSP in Insect Defense. | 2016 | PLoS ONE | pmid:27167733 |
Fu X et al. | Regulation of formation of volatile compounds of tea (Camellia sinensis) leaves by single light wavelength. | 2015 | Sci Rep | pmid:26567525 |
Guyenet SJ and Carlson SE | Increase in adipose tissue linoleic acid of US adults in the last half century. | 2015 | Adv Nutr | pmid:26567191 |
Phan CW et al. | Uridine from Pleurotus giganteus and Its Neurite Outgrowth Stimulatory Effects with Underlying Mechanism. | 2015 | PLoS ONE | pmid:26565787 |
Shivashankar S and Sumathi M | Do seed VLCFAs trigger spongy tissue formation in Alphonso mango by inducing germination? | 2015 | J. Biosci. | pmid:25963264 |
Hirata A et al. | A novel unsaturated fatty acid hydratase toward C16 to C22 fatty acids from Lactobacillus acidophilus. | 2015 | J. Lipid Res. | pmid:25966711 |
Kim SY et al. | Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway. | 2015 | Int. J. Mol. Med. | pmid:25672876 |