Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jarret RL and Levy IJ | Oil and fatty acid contents in seed of Citrullus lanatus Schrad. | 2012 | J. Agric. Food Chem. | pmid:22540530 |
Macaluso F et al. | Effect of conjugated linoleic acid on testosterone levels in vitro and in vivo after an acute bout of resistance exercise. | 2012 | J Strength Cond Res | pmid:22614148 |
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Osuji GO et al. | Molecular modeling of metabolism for allergen-free low linoleic acid peanuts. | 2012 | Appl. Biochem. Biotechnol. | pmid:22918723 |
Kim YS et al. | In vitro protective effects of Thymus quinquecostatus Celak extracts on t-BHP-induced cell damage through antioxidant activity. | 2012 | Food Chem. Toxicol. | pmid:22921350 |
Mukherjee S et al. | NAD(P)H cytochrome b5 oxidoreductase deficiency in Leishmania major results in impaired linoleate synthesis followed by increased oxidative stress and cell death. | 2012 | J. Biol. Chem. | pmid:22923617 |
Le Maux S et al. | β-Lactoglobulin as a molecular carrier of linoleate: characterization and effects on intestinal epithelial cells in vitro. | 2012 | J. Agric. Food Chem. | pmid:22924475 |
Ramos Morales E et al. | Ricinoleic acid inhibits methanogenesis and fatty acid biohydrogenation in ruminal digesta from sheep and in bacterial cultures. | 2012 | J. Anim. Sci. | pmid:22829608 |
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Eserian JK et al. | Effects of polyunsaturated fatty acids on cocaine-conditioned place preference in mice. | 2012 | Nutr Neurosci | pmid:22390908 |
Steffen BT et al. | Obesity modifies the association between plasma phospholipid polyunsaturated fatty acids and markers of inflammation: the Multi-Ethnic Study of Atherosclerosis. | 2012 | Int J Obes (Lond) | pmid:21829163 |
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Burrows T et al. | A comparative validation of a child food frequency questionnaire using red blood cell membrane fatty acids. | 2012 | Eur J Clin Nutr | pmid:22378224 |
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Shin D et al. | Effects of dietary combination of n-3 and n-9 fatty acids on the deposition of linoleic and arachidonic acid in broiler chicken meats. | 2012 | Poult. Sci. | pmid:22399741 |
Billault I et al. | Probing substrate-product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes. | 2012 | Anal Bioanal Chem | pmid:22349323 |
Khan R et al. | Variation in oil content and fatty acid composition of the seed oil of Acacia species collected from the northwest zone of India. | 2012 | J. Sci. Food Agric. | pmid:22351513 |
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Novak EM et al. | Low linoleic acid may facilitate Δ6 desaturase activity and docosahexaenoic acid accretion in human fetal development. | 2012 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22365109 |
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Gull J et al. | Variation in antioxidant attributes at three ripening stages of guava (Psidium guajava L.) fruit from different geographical regions of Pakistan. | 2012 | Molecules | pmid:22418924 |
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Wakabayashi K et al. | Species differences in toxicokinetic parameters of glycidol after a single dose of glycidol or glycidol linoleate in rats and monkeys. | 2012 | J Toxicol Sci | pmid:22863850 |
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Kang J et al. | Identification of three genes encoding microsomal oleate desaturases (FAD2) from the oilseed crop Camelina sativa. | 2011 | Plant Physiol. Biochem. | pmid:21215650 |
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