Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sánchez-Vioque R et al. | Interaction of chickpea (Cicer arietinum L.) legumin with oxidized linoleic acid. | 1999 | J. Agric. Food Chem. | pmid:10552371 |
Domingo N et al. | Effects of dexamethasone and linoleic acid on hepatic secretion of biliary lipids and anionic polypeptide factor: In vivo and in vitro studies. | 1999 Nov-Dec | Digestion | pmid:10545720 |
Kulkarni AP and Sajan M | Lipoxygenase-another pathway for glutathione conjugation of xenobiotics: A study with human term placental lipoxygenase and ethacrynic acid. | 1999 | Arch. Biochem. Biophys. | pmid:10545208 |
Murphy J et al. | Fat malabsorption in cystic fibrosis patients. | 1999 | Am. J. Clin. Nutr. | pmid:10539762 |
Rose DP and Connolly JM | Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice. | 1999 | Int. J. Oncol. | pmid:10536186 |
Dhiman TR et al. | Conjugated linoleic acid content of milk from cows fed different diets. | 1999 | J. Dairy Sci. | pmid:10531600 |
Howard FA and Henderson C | Hydrogenation of polyunsaturated fatty acids by human colonic bacteria. | 1999 | Lett. Appl. Microbiol. | pmid:10530040 |
Filley SJ et al. | Prostaglandin f(2alpha) concentrations, fatty acid profiles, and fertility in lipid-infused postpartum beef heifers. | 1999 | Biol. Reprod. | pmid:10529280 |
Dauchy RT et al. | Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism. | 1999 | Cancer Lett. | pmid:10529012 |
Minich DM et al. | Biliary phospholipid secretion is not required for intestinal absorption and plasma status of linoleic acid in mice. | 1999 | Biochim. Biophys. Acta | pmid:10526224 |