Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Chamruspollert M and Sell JL | Transfer of dietary conjugated linoleic acid to egg yolks of chickens. | 1999 | Poult. Sci. | pmid:10472840 |
Meek S et al. | Microcystin affinity purification of plant protein phosphatases: PP1C, PP5 and a regulatory A-subunit of PP2A. | 1999 | FEBS Lett. | pmid:10471836 |
Park JY et al. | Role of hyperpolarization attained by linoleic acid in chick myoblast fusion. | 1999 | Exp. Cell Res. | pmid:10471316 |
Helge JW et al. | Regular exercise modulates muscle membrane phospholipid profile in rats. | 1999 | J. Nutr. | pmid:10460197 |
Warnotte C et al. | Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. | 1999 | Mol. Cell. Endocrinol. | pmid:10459862 |
Lipkin M et al. | Dietary factors in human colorectal cancer. | 1999 | Annu. Rev. Nutr. | pmid:10448536 |
Sammon AM | Dietary linoleic acid, immune inhibition and disease. | 1999 | Postgrad Med J | pmid:10448487 |
Lundell KH et al. | Plasma metabolites after a lipid load in infants with congenital heart disease. | 1999 | Acta Paediatr. | pmid:10447129 |
Freese R et al. | Green tea extract decreases plasma malondialdehyde concentration but does not affect other indicators of oxidative stress, nitric oxide production, or hemostatic factors during a high-linoleic acid diet in healthy females. | 1999 | Eur J Nutr | pmid:10443337 |
Jarmuszkiewicz W et al. | Identification and characterization of a protozoan uncoupling protein in Acanthamoeba castellanii. | 1999 | J. Biol. Chem. | pmid:10438491 |