Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ahn DU et al. | Effect of dietary conjugated linoleic acid on the quality characteristics of chicken eggs during refrigerated storage. | 1999 | Poult. Sci. | pmid:10438141 |
Rudel LL | Atherosclerosis and conjugated linoleic acid. | 1999 | Br. J. Nutr. | pmid:10434843 |
Yamasaki M et al. | Dietary effect of conjugated linoleic acid on lipid levels in white adipose tissue of Sprague-Dawley rats. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10427699 |
Calvo AM et al. | Sporogenic effect of polyunsaturated fatty acids on development of Aspergillus spp. | 1999 | Appl. Environ. Microbiol. | pmid:10427064 |
Demmelmair H et al. | Comparison of bolus versus fractionated oral applications of [13C]-linoleic acid in humans. | 1999 | Eur. J. Clin. Invest. | pmid:10411666 |
Sammon AM | Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10410386 |
Kim S et al. | C/EBPbeta (NF-M) is essential for activation of the p20K lipocalin gene in growth-arrested chicken embryo fibroblasts. | 1999 | Mol. Cell. Biol. | pmid:10409760 |
Ding XZ et al. | Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10405349 |
Murakami K et al. | Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403814 |
Dontsov AE et al. | Retinal pigment epithelium pigment granules stimulate the photo-oxidation of unsaturated fatty acids. | 1999 | Free Radic. Biol. Med. | pmid:10401607 |