| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Cogo PE et al. | Endogenous surfactant metabolism in critically ill infants measured with stable isotope labeled fatty acids. | 1999 | Pediatr. Res. | pmid:10022597 |
| Umezawa M et al. | High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice. | 1999 | J. Nutr. | pmid:10024623 |
| Cunnane SC | The long history of essential fatty acids but belated knowledge about linoleate deficiency per se: a paradox. | 1999 | J. Nutr. | pmid:10024625 |
| Aki T et al. | Molecular cloning and functional characterization of rat delta-6 fatty acid desaturase. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10049752 |
| Avery SV et al. | Stimulation of strontium accumulation in linoleate-enriched Saccharomyces cerevisiae is a result of reduced Sr2+ efflux. | 1999 | Appl. Environ. Microbiol. | pmid:10049882 |
| Josyula S et al. | Inhibition of DNA adduct formation of PhIP in female F344 rats by dietary conjugated linoleic acid. | 1998 | Nutr Cancer | pmid:10050262 |
| Josyula S and Schut HA | Effects of dietary conjugated linoleic acid on DNA adduct formation of PhIP and IQ after bolus administration to female F344 rats. | 1998 | Nutr Cancer | pmid:10050263 |
| Jussila M et al. | Separation of linoleic acid oxidation products by micellar electrokinetic capillary chromatography and nonaqueous capillary electrophoresis. | 1999 | Electrophoresis | pmid:10065966 |
| Rukkwamsuk T et al. | Hepatic fatty acid composition in periparturient dairy cows with fatty liver induced by intake of a high energy diet in the dry period. | 1999 | J. Dairy Sci. | pmid:10068949 |
| Dhiman TR et al. | Conjugated linoleic acid content of milk and cheese from cows fed extruded oilseeds. | 1999 | J. Dairy Sci. | pmid:10068962 |
| Chancharme L et al. | Cholesteryl ester hydroperoxide lability is a key feature of the oxidative susceptibility of small, dense LDL. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:10073990 |
| Olsson U et al. | Fatty acids modulate the composition of extracellular matrix in cultured human arterial smooth muscle cells by altering the expression of genes for proteoglycan core proteins. | 1999 | Diabetes | pmid:10078565 |
| Brodie AE et al. | Conjugated linoleic acid inhibits differentiation of pre- and post- confluent 3T3-L1 preadipocytes but inhibits cell proliferation only in preconfluent cells. | 1999 | J. Nutr. | pmid:10082762 |
| Galli A et al. | High-level expression of rat class I alcohol dehydrogenase is sufficient for ethanol-induced fat accumulation in transduced HeLa cells. | 1999 | Hepatology | pmid:10094961 |
| Stewart JM et al. | Comparisons of the effects of temperature on the liver fatty acid binding proteins from hibernator and nonhibernator mammals. | 1998 | Biochem. Cell Biol. | pmid:10099779 |
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| DeLany JP et al. | Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake. | 1999 | Am. J. Physiol. | pmid:10198400 |
| Bergamini S et al. | Prooxidant activity of ferrioxamine in isolated rat hepatocytes and linoleic acid micelles. | 1999 | Chem. Res. Toxicol. | pmid:10207126 |
| Spaide RF et al. | Characterization of peroxidized lipids in Bruch's membrane. | 1999 | Retina (Philadelphia, Pa.) | pmid:10213241 |
| Minich DM et al. | Bile diversion in rats leads to a decreased plasma concentration of linoleic acid which is not due to decreased net intestinal absorption of dietary linoleic acid. | 1999 | Biochim. Biophys. Acta | pmid:10216285 |
| Cortez-Pinto H et al. | Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. | 1999 | Gastroenterology | pmid:10220511 |
| Banni S et al. | An increase in vitamin A status by the feeding of conjugated linoleic acid. | 1999 | Nutr Cancer | pmid:10227044 |
| Szitanyi P et al. | Metabolism of 13C-labeled linoleic acid in newborn infants during the first week of life. | 1999 | Pediatr. Res. | pmid:10231862 |
| Iuliano L et al. | Protection of low density lipoprotein oxidation by the antioxidant agent IRFI005, a new synthetic hydrophilic vitamin E analogue. | 1999 | Free Radic. Biol. Med. | pmid:10232829 |
| Burke PA et al. | Conditionally essential fatty acid deficiencies in end-stage liver disease. | 1999 | Nutrition | pmid:10319364 |
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| Haggarty P et al. | Effect of maternal polyunsaturated fatty acid concentration on transport by the human placenta. | 1999 | Biol. Neonate | pmid:10325438 |
| Wei T et al. | Antioxidant properties of EPC-K1: a study on mechanisms. | 1999 | Biophys. Chem. | pmid:10326248 |
| Kapich A et al. | Coupling of manganese peroxidase-mediated lipid peroxidation with destruction of nonphenolic lignin model compounds and 14C-labeled lignins. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10334942 |
| Nuñez A et al. | Cofactor recycling in a coupled enzyme oxidation-reduction reaction: conversion of omega-oxo-fatty acids into omega-hydroxy and dicarboxylic acids. | 1999 | Biotechnol. Appl. Biochem. | pmid:10334949 |
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| Meuillet EJ et al. | Incorporation of exogenous lipids modulates insulin signaling in the hepatoma cell line, HepG2. | 1999 | Biochim. Biophys. Acta | pmid:10354513 |
| Fukushima M et al. | Effects of a mixture of organisms, Lactobacillus acidophilus or Streptococcus faecalis on delta6-desaturase activity in the livers of rats fed a fat- and cholesterol-enriched diet. | 1999 | Nutrition | pmid:10355850 |
| Hilakivi-Clarke L et al. | The influence of maternal diet on breast cancer risk among female offspring. | 1999 | Nutrition | pmid:10355854 |
| Alava MA et al. | Fatty acid desaturation: effect of alphafetoprotein on alpha-linolenic acid conversion by fetal rat hepatocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10359023 |
| Dodge ML et al. | Glutathione peroxidase activity modulates fatty acid profiles of plasma and breast milk in Chinese women. | 1999 | J Trace Elem Med Biol | pmid:10365375 |
| Stimers JR et al. | Effects of linoleic acid metabolites on electrical activity in adult rat ventricular myocytes. | 1999 | Biochim. Biophys. Acta | pmid:10366778 |
| Kavanaugh CJ et al. | Effect of dietary conjugated linoleic acid on phorbol ester-induced PGE2 production and hyperplasia in mouse epidermis. | 1999 | Nutr Cancer | pmid:10368807 |
| Gänzle MG et al. | Resistance of Escherichia coli and Salmonella against nisin and curvacin A. | 1999 | Int. J. Food Microbiol. | pmid:10375133 |
| Forster C et al. | Molecular analysis of a null mutant for pea (Pisum sativum L.) seed lipoxygenase-2. | 1999 | Plant Mol. Biol. | pmid:10380807 |
| Akeo K et al. | Effects of fluorescent light on growth of bovine retinal pigment epithelial cells in vitro incubated with linoleic acid or linoleic acid hydroperoxide. | 1999 | Pigment Cell Res. | pmid:10385917 |
| Parodi PW | Conjugated linoleic acid and other anticarcinogenic agents of bovine milk fat. | 1999 | J. Dairy Sci. | pmid:10386321 |
| Greenberg D et al. | Differential satiating effects of fats in the small intestine of obesity-resistant and obesity-prone rats. | 1999 | Physiol. Behav. | pmid:10386906 |
| Jiang J et al. | Relation between the intake of milk fat and the occurrence of conjugated linoleic acid in human adipose tissue. | 1999 | Am. J. Clin. Nutr. | pmid:10393134 |
| Jeppesen PB et al. | Differences in essential fatty acid requirements by enteral and parenteral routes of administration in patients with fat malabsorption. | 1999 | Am. J. Clin. Nutr. | pmid:10393142 |
| Su HM et al. | Linoleic acid kinetics and conversion to arachidonic acid in the pregnant and fetal baboon. | 1999 | J. Lipid Res. | pmid:10393215 |
| Ando H et al. | Possible involvement of proteolytic degradation of tyrosinase in the regulatory effect of fatty acids on melanogenesis. | 1999 | J. Lipid Res. | pmid:10393216 |
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