| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gargouri M and Legoy MD | The kinetic behaviour of a two-enzyme system in biphasic media: coupling hydrolysis and lipoxygenation. | 1997 | Biochim. Biophys. Acta | pmid:9048899 |
| Chen ZY et al. | Depletion of linoleate induced by weight cycling is independent of extent of calorie restriction. | 1997 | Am. J. Physiol. | pmid:9038989 |
| Solà R et al. | Oleic acid rich diet protects against the oxidative modification of high density lipoprotein. | 1997 | Free Radic. Biol. Med. | pmid:9034243 |
| Black PN and Sharpe S | Dietary fat and asthma: is there a connection? | 1997 | Eur. Respir. J. | pmid:9032484 |
| Brun T et al. | Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1. | 1997 | Diabetes | pmid:9032094 |
| Cogo PE et al. | Simultaneous measurement of the rates of appearance of palmitic and linoleic acid in critically ill infants. | 1997 | Pediatr. Res. | pmid:9029635 |
| Hayashi T et al. | Stimulation of cell proliferation and inhibition of gap junctional intercellular communication by linoleic acid. | 1997 | Cancer Lett. | pmid:9029175 |
| Staprans I et al. | Oxidized lipids in the diet are incorporated by the liver into very low density lipoprotein in rats. | 1996 | J. Lipid Res. | pmid:9026539 |
| Sheaff Greiner RC et al. | Linoleate, alpha-linolenate, and docosahexaenoate recycling into saturated and monounsaturated fatty acids is a major pathway in pregnant or lactating adults and fetal or infant rhesus monkeys. | 1996 | J. Lipid Res. | pmid:9017518 |
| Kubin A et al. | Wavelength-dependent photoresponse of biological and aqueous model systems using the photodynamic plant pigment hypericin. | 1996 | J. Photochem. Photobiol. B, Biol. | pmid:9002246 |
| Kinter M et al. | Oleic acid incorporation protects cultured hamster fibroblasts from oxygen-induced cytotoxicity. | 1996 | J. Nutr. | pmid:9001361 |
| Tsukamoto S et al. | Effects of bezafibrate on ethanol oxidation in rats. | 1996 | Alcohol. Clin. Exp. Res. | pmid:8986210 |
| Hulea SA et al. | Bilirubin sensitized photooxidation of human plasma low density lipoprotein. | 1996 | Biochim. Biophys. Acta | pmid:8982266 |
| Pregnolato P et al. | Effect of diets containing different amounts of precursor and derivative fatty acids on serum TXB2. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8981629 |
| Mustad VA et al. | Dietary linoleic acid increases and palmitic acid decreases hepatic LDL receptor protein and mRNA abundance in young pigs. | 1996 | J. Lipid Res. | pmid:8978483 |
| Applegate TJ and Sell JL | Effect of dietary linoleic to linolenic acid ratio and vitamin E supplementation on vitamin E status of poults. | 1996 | Poult. Sci. | pmid:8966177 |
| Matsuo N et al. | Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951990 |
| Shen J et al. | Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development. | 1996 | J. Clin. Invest. | pmid:8941635 |
| Ranganath LR et al. | Increased mean platelet volume after oestrogen replacement therapy. | 1996 | Ann. Clin. Biochem. | pmid:8937589 |
| Sugano M and Ikeda I | Metabolic interactions between essential and trans-fatty acids. | 1996 | Curr. Opin. Lipidol. | pmid:8925188 |