Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Dhiman TR et al. Conjugated linoleic acid content of milk and cheese from cows fed extruded oilseeds. 1999 J. Dairy Sci. pmid:10068962
Chancharme L et al. Cholesteryl ester hydroperoxide lability is a key feature of the oxidative susceptibility of small, dense LDL. 1999 Arterioscler. Thromb. Vasc. Biol. pmid:10073990
Olsson U et al. Fatty acids modulate the composition of extracellular matrix in cultured human arterial smooth muscle cells by altering the expression of genes for proteoglycan core proteins. 1999 Diabetes pmid:10078565
Brodie AE et al. Conjugated linoleic acid inhibits differentiation of pre- and post- confluent 3T3-L1 preadipocytes but inhibits cell proliferation only in preconfluent cells. 1999 J. Nutr. pmid:10082762
Galli A et al. High-level expression of rat class I alcohol dehydrogenase is sufficient for ethanol-induced fat accumulation in transduced HeLa cells. 1999 Hepatology pmid:10094961
Stewart JM et al. Comparisons of the effects of temperature on the liver fatty acid binding proteins from hibernator and nonhibernator mammals. 1998 Biochem. Cell Biol. pmid:10099779
Augé N et al. Uptake of 13-hydroperoxylinoleic acid by cultured cells. 1999 Arterioscler. Thromb. Vasc. Biol. pmid:10195919
Jayawickreme SP et al. Regulation of 15-lipoxygenase expression and mucus secretion by IL-4 in human bronchial epithelial cells. 1999 Am. J. Physiol. pmid:10198357
DeLany JP et al. Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake. 1999 Am. J. Physiol. pmid:10198400
Bergamini S et al. Prooxidant activity of ferrioxamine in isolated rat hepatocytes and linoleic acid micelles. 1999 Chem. Res. Toxicol. pmid:10207126