| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Battu S et al. | Linoleic acid peroxidation by Solanum tuberosum lipoxygenase was activated in the presence of human 5-lipoxygenase-activating protein. | 1998 | Biochim. Biophys. Acta | pmid:9630716 |
| Hughes RK et al. | Characterization of authentic recombinant pea-seed lipoxygenases with distinct properties and reaction mechanisms. | 1998 | Biochem. J. | pmid:9639559 |
| Iwase H et al. | Formation of keto and hydroxy compounds of linoleic acid in submitochondrial particles of bovine heart. | 1998 | Free Radic. Biol. Med. | pmid:9641268 |
| Murthy S et al. | 13-hydroxy octadecadienoic acid (13-HODE) inhibits triacylglycerol-rich lipoprotein secretion by CaCo-2 cells. | 1998 | J. Lipid Res. | pmid:9643357 |
| Aarsland A and Wolfe RR | Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men. | 1998 | J. Lipid Res. | pmid:9643360 |
| Kagan VE et al. | Plasma membrane NADH-coenzyme Q0 reductase generates semiquinone radicals and recycles vitamin E homologue in a superoxide-dependent reaction. | 1998 | FEBS Lett. | pmid:9645471 |
| Scimeca JA | Toxicological evaluation of dietary conjugated linoleic acid in male Fischer 344 rats. | 1998 | Food Chem. Toxicol. | pmid:9662414 |
| Erickson KL | Is there a relation between dietary linoleic acid and cancer of the breast, colon, or prostate? | 1998 | Am. J. Clin. Nutr. | pmid:9665090 |
| Zock PL and Katan MB | Linoleic acid intake and cancer risk: a review and meta-analysis. | 1998 | Am. J. Clin. Nutr. | pmid:9665108 |
| Pitchumoni S et al. | Reoxygenation injury affects isolated islet response to fatty acid stimulation. | 1998 | Metab. Clin. Exp. | pmid:9667226 |
| Guarini P et al. | Effects of dietary fish oil and soy phosphatidylcholine on neutrophil fatty acid composition, superoxide release, and adhesion. | 1998 | Inflammation | pmid:9675609 |
| Kelly ML et al. | Effect of intake of pasture on concentrations of conjugated linoleic acid in milk of lactating cows. | 1998 | J. Dairy Sci. | pmid:9684170 |
| Demmelmair H et al. | Metabolism of U13C-labeled linoleic acid in lactating women. | 1998 | J. Lipid Res. | pmid:9684741 |
| Kang LT and Vanderhoek JY | Mono (S) hydroxy fatty acids: novel ligands for cytosolic actin. | 1998 | J. Lipid Res. | pmid:9684751 |
| Kato M et al. | Reactivity of soybean lipoxygenase-1 to linoleic acid entrapped in phosphatidylcholine vesicles. | 1998 | J. Biochem. | pmid:9685717 |
| Fungwe TV et al. | Fatty acids modulate lecithin:cholesterol acyltransferase secretion independently of effects on triglyceride secretion in primary rat hepatocytes. | 1998 | J. Nutr. | pmid:9687543 |
| Letawe C et al. | Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones. | 1998 | Clin. Exp. Dermatol. | pmid:9692305 |
| Hsu AF et al. | Characterization of soybean lipoxygenase immobilized in cross-linked phyllosilicates. | 1998 | Biotechnol. Appl. Biochem. | pmid:9693089 |
| Goodrich-Tanrikulu M et al. | Changes in fatty acid composition of Neurospora crassa accompany sexual development and ascospore germination. | 1998 | Microbiology (Reading, Engl.) | pmid:9695905 |
| Yamaguchi H et al. | High transepidermal water loss induces fatty acid synthesis and cutaneous fatty acid-binding protein expression in rat skin. | 1998 | J. Dermatol. Sci. | pmid:9697049 |