Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Nakashima R et al. Exposure to DEHP decreased four fatty acid levels in plasma of prepartum mice. 2013 Toxicology pmid:23619606
Ivanova L et al. Phomenins and fatty acids from Alternaria infectoria. 2010 Toxicon pmid:20060014
Amminger GP et al. Predictors of treatment response in young people at ultra-high risk for psychosis who received long-chain omega-3 fatty acids. 2015 Transl Psychiatry pmid:25585167
Lausada N et al. Effect of cyclosporine and sirolimus on fatty acid desaturase activities in cultured HEPG2 cells. 2009 Transplant. Proc. pmid:19545746
Perez RV et al. Dietary immunoregulation of transfusion-induced immunosuppression. 1988 Transplantation pmid:3258077
Tchervenkov JI et al. The effect of donor-specific blood transfusion, cyclosporine, and dietary prostaglandin precursors on rat cardiac allograft survival. II. Effectiveness of a 24-hour induction period with DST and CsA in inducing long-term graft survival. 1989 Transplantation pmid:2643225
Perez RV et al. Augmentation of donor-specific transfusion and cyclosporine effects with dietary linoleic acid. 1989 Transplantation pmid:2660353
Hansen HS Linoleic acid as a precursor for acylation of transducin, a retinol G protein? 1993 Trends Biochem. Sci. pmid:8328015
Blée E Impact of phyto-oxylipins in plant defense. 2002 Trends Plant Sci. pmid:12119169
Nguyen LQ et al. Intake of essential fatty acids by growing-finishing pigs kept on smallholdings in central Vietnam. 2005 Trop Anim Health Prod pmid:15729898