Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Ingkaninan K et al. Interference of linoleic acid fraction in some receptor binding assays. 1999 J. Nat. Prod. pmid:10395519
Andersen LF et al. Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum. 1999 Am. J. Epidemiol. pmid:10400557
O'Donnell VB et al. 15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase. 1999 J. Biol. Chem. pmid:10400618
Dontsov AE et al. Retinal pigment epithelium pigment granules stimulate the photo-oxidation of unsaturated fatty acids. 1999 Free Radic. Biol. Med. pmid:10401607
Murakami K et al. Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. 1999 Biochem. Biophys. Res. Commun. pmid:10403814
Ding XZ et al. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. 1999 Biochem. Biophys. Res. Commun. pmid:10405349
Kim S et al. C/EBPbeta (NF-M) is essential for activation of the p20K lipocalin gene in growth-arrested chicken embryo fibroblasts. 1999 Mol. Cell. Biol. pmid:10409760
Sammon AM Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. 1999 Prostaglandins Other Lipid Mediat. pmid:10410386
Demmelmair H et al. Comparison of bolus versus fractionated oral applications of [13C]-linoleic acid in humans. 1999 Eur. J. Clin. Invest. pmid:10411666
Calvo AM et al. Sporogenic effect of polyunsaturated fatty acids on development of Aspergillus spp. 1999 Appl. Environ. Microbiol. pmid:10427064