| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Linoleic acid
Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoleic acid?
Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoleic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoleic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with Linoleic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoleic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoleic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoleic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoleic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chavali SR and Forse RA | Decreased production of interleukin-6 and prostaglandin E2 associated with inhibition of delta-5 desaturation of omega6 fatty acids in mice fed safflower oil diets supplemented with sesamol. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10718106 |
| Baron CP et al. | Peroxidation of linoleate at physiological pH: hemichrome formation by substrate binding protects against metmyoglobin activation by hydrogen peroxide. | 2000 | Free Radic. Biol. Med. | pmid:10719236 |
| Fidler N et al. | Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women. | 1999 | Ann. Nutr. Metab. | pmid:10725767 |
| Adam O | Linoleic acid - the fall of an angel? | 1999 | Ann. Nutr. Metab. | pmid:10725772 |
| Draper AJ and Hammock BD | Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. | 2000 | Arch. Biochem. Biophys. | pmid:10729206 |
| Kemp B et al. | Influence of linoleic/linolenic acid ratio in the diet of periparturient cattle on plasma concentrations of PGF2 alpha metabolite and placental expulsion rate. | 1998 | Theriogenology | pmid:10732036 |
| Hochi S et al. | Effect of linoleic acid-albumin in the culture medium on freezing sensitivity of in vitro-produced bovine morulae. | 1999 | Theriogenology | pmid:10734383 |
| Clemmesen JO et al. | Plasma phospholipid fatty acid pattern in severe liver disease. | 2000 | J. Hepatol. | pmid:10735619 |
| Hudson JA et al. | Identification and enumeration of oleic acid and linoleic acid hydrating bacteria in the rumen of sheep and cows. | 2000 | J. Appl. Microbiol. | pmid:10735997 |
| Larqué E et al. | Dietary trans fatty acids affect the essential fatty-acid concentration of rat milk. | 2000 | J. Nutr. | pmid:10736340 |
| Whalen MM et al. | Lysophosphatidylcholine and arachidonic acid are required in the cytotoxic response of human natural killer cells to tumor target cells. | 1999 | Cell. Physiol. Biochem. | pmid:10749996 |
| Garcia HS et al. | Interesterification (acidolysis) of butterfat with conjugated linoleic acid in a batch reactor. | 2000 | J. Dairy Sci. | pmid:10750090 |
| Rubbo H et al. | Nitric oxide reaction with lipid peroxyl radicals spares alpha-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/alpha-tocopherol than alpha-tocopherol/ascorbate. | 2000 | J. Biol. Chem. | pmid:10753874 |
| Trimborn M et al. | Linoleic acid cytotoxicity to bovine lens epithelial cells: influence of albumin on linoleic acid uptake and cytotoxicity. | 2000 Mar-Jun | Ophthalmic Res. | pmid:10754440 |
| Hubbard NE et al. | Reduction of murine mammary tumor metastasis by conjugated linoleic acid. | 2000 | Cancer Lett. | pmid:10755392 |
| Punchard NA et al. | Analysis of the intestinal absorption of essential fatty acids in vivo in the rat. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765976 |
| Mohan IK and Das UN | Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765977 |
| Littman ED et al. | Role of protein kinase C isoenzymes in fatty acid stimulation of insulin secretion. | 2000 | Pancreas | pmid:10766451 |
| Mogul R et al. | Oleyl sulfate reveals allosteric inhibition of soybean lipoxygenase-1 and human 15-lipoxygenase. | 2000 | Biochemistry | pmid:10769137 |
| Kritharides L | Ascorbic acid and copper in linoleate oxidation--Dunkley revisited. | 1999 | Redox Rep. | pmid:10772064 |