Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Yousr M and Howell N Antioxidant and ACE Inhibitory Bioactive Peptides Purified from Egg Yolk Proteins. 2015 Int J Mol Sci pmid:26690134
Liu HC et al. Transcriptome changes in Polygonum multiflorum Thunb. roots induced by methyl jasmonate. 2015 J Zhejiang Univ Sci B pmid:26642186
Liang S et al. Physicochemical Properties and Fatty Acid Profiles of Elaeagnus mollis Diels Nut Oils. 2015 J Oleo Sci pmid:26632946
Qian Z et al. Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice. 2015 Sci Rep pmid:26615818
Lee CW et al. Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin. 2015 Biochem. Biophys. Res. Commun. pmid:26206084
Hoenselaar R Letter by Hoenselaar Regarding Article, "Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies". 2015 Circulation pmid:26195491
Yuan T et al. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. 2015 Int J Clin Exp Pathol pmid:26191198
Marinho GS et al. Lipids and Composition of Fatty Acids of Saccharina latissima Cultivated Year-Round in Integrated Multi-Trophic Aquaculture. 2015 Mar Drugs pmid:26184241
Salehi R et al. A prepartum diet supplemented with oilseeds high in oleic or linoleic acid reduced GnRH-induced LH release in dairy cows during second week postpartum. 2015 Reprod. Biol. Endocrinol. pmid:26138920
Grevengoed TJ et al. Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. 2015 J. Lipid Res. pmid:26136511
Hasiewicz-Derkacz K et al. Natural phenolics greatly increase flax (Linum usitatissimum) oil stability. 2015 BMC Biotechnol. pmid:26123633
Rosero DS et al. Impact of dietary lipids on sow milk composition and balance of essential fatty acids during lactation in prolific sows. 2015 J. Anim. Sci. pmid:26115280
Alsaidan M et al. Cells to Surgery Quiz: July 2015. 2015 J. Invest. Dermatol. pmid:26066894
Schumann T et al. Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment. 2015 Oncotarget pmid:25968567
Negrini R et al. pH-responsive lyotropic liquid crystals and their potential therapeutic role in cancer treatment. 2015 Chem. Commun. (Camb.) pmid:25783035
Clouard C et al. Dietary linoleic and α-linolenic acids affect anxiety-related responses and exploratory activity in growing pigs. 2015 J. Nutr. pmid:25644359
Reinders I et al. Plasma phospholipid PUFAs are associated with greater muscle and knee extension strength but not with changes in muscle parameters in older adults. 2015 J. Nutr. pmid:25355842
Baylin A et al. Serum Trans Fatty Acids Are Not Associated with Weight Gain or Linear Growth in School-Age Children. 2015 J. Nutr. pmid:26180252
Kim SY et al. Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway. 2015 Int. J. Mol. Med. pmid:25672876
Okazaki H et al. Bongkrekic acid as a selective activator of the peroxisome proliferator-activated receptor γ (PPARγ) isoform. 2015 J Toxicol Sci pmid:25786526