Linoleic acid

Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids.

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Introduction

To understand associated biological information of Linoleic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoleic acid?

Linoleic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Chronic Obstructive Airway Disease, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoleic acid

PubChem Associated disorders and diseases

What pathways are associated with Linoleic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with Linoleic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoleic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoleic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoleic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoleic acid

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Authors Title Published Journal PubMed Link
Siefken W et al. Regulation of cholesterol synthesis by oleic and palmitic acid in keratinocytes. 2000 Exp. Dermatol. pmid:10772388
Sasaki T et al. Dietary docosahexaenoic acid can alter the surface expression of CD4 and CD8 on T cells in peripheral blood. 2000 J. Agric. Food Chem. pmid:10775347
Liégeois C et al. Measuring antioxidant efficiency of wort, malt, and hops against the 2,2'-azobis(2-amidinopropane) dihydrochloride-induced oxidation of an aqueous dispersion of linoleic acid. 2000 J. Agric. Food Chem. pmid:10775361
Talcott ST et al. Antioxidant changes and sensory properties of carrot puree processed with and without periderm tissue. 2000 J. Agric. Food Chem. pmid:10775391
Hover CG and Kulkarni AP A simple and efficient method for hemoglobin removal from mammalian tissue cytosol by zinc sulfate and its application to the study of lipoxygenase. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780874
Charnock JS Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780878
McCarty MF Toward a wholly nutritional therapy for type 2 diabetes. 2000 Med. Hypotheses pmid:10783493
McEvoy TG et al. Fatty acid composition of lipids in immature cattle, pig and sheep oocytes with intact zona pellucida. 2000 J. Reprod. Fertil. pmid:10793638
Mandin O et al. Volatile compounds from potato-like model systems. 1999 J. Agric. Food Chem. pmid:10794636
Kaya A Properties and stability of butter oil obtained from milk and yoghurt. 2000 Nahrung pmid:10795582
Itokazu N et al. Bidirectional actions of docosahexaenoic acid on hippocampal neurotransmissions in vivo. 2000 Brain Res. pmid:10799687
Gupta SV and Khosla P Pork fat and chicken fat similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. 2000 J. Nutr. pmid:10801922
Iwase H et al. Effect of cytochrome c on the linoleic acid-degrading activity of porcine leukocyte 12-lipoxygenase. 2000 Free Radic. Biol. Med. pmid:10802222
Kachhap SK et al. Effect of omega-6 polyunsaturated fatty acid (linoleic acid) on BRCA1 gene expression in MCF-7 cell line. 2000 Cancer Lett. pmid:10806298
Lapillonne A et al. Effects of liver transplantation on long-chain polyunsaturated fatty acid status in infants with biliary atresia. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:10817283
Decsi T et al. Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life. 2000 J. Pediatr. Gastroenterol. Nutr. pmid:10817286
Pham TQ et al. Antioxidant properties of crocin from Gardenia jasminoides Ellis and study of the reactions of crocin with linoleic acid and crocin with oxygen. 2000 J. Agric. Food Chem. pmid:10820042
Dhiman TR et al. Conjugated linoleic acid (CLA) content of milk from cows offered diets rich in linoleic and linolenic acid. 2000 J. Dairy Sci. pmid:10821577
Tominaga K et al. Effect of linoleic acid-albumin on post-thaw survival of in vitro-produced bovine embryos at the 16-cell stage. 2000 J. Vet. Med. Sci. pmid:10823739
Peebles ED et al. Effects of dietary fat type and level on broiler breeder performance. 2000 Poult. Sci. pmid:10824949