Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Refractive Errors D012030 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Onchocerciasis D009855 1 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Liposarcoma D008080 1 associated lipids
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Hicks M et al. Catalysis of lipid peroxidation by glucose and glycosylated collagen. 1988 Biochem. Biophys. Res. Commun. pmid:3126742
Bandyopadhyay GK et al. Proliferative effects of insulin and epidermal growth factor on mouse mammary epithelial cells in primary culture. Enhancement by hydroxyeicosatetraenoic acids and synergism with prostaglandin E2. 1988 J. Biol. Chem. pmid:3286636
Truchetet E et al. [Skin changes, pathophysiology and therapy in deficiency of essential fatty acids]. 1988 Z. Hautkr. pmid:3291438
Beaumelle BD and Vial HJ Uninfected red cells from malaria-infected blood: alteration of fatty acid composition involving a serum protein: an in vivo and in vitro study. 1988 In Vitro Cell. Dev. Biol. pmid:3294227
Shimokawa T et al. Effect of dietary alpha-linolenate/linoleate balance on mean survival time, incidence of stroke and blood pressure of spontaneously hypertensive rats. 1988 Life Sci. pmid:2905408
Bartels T et al. Correlations between endogenous prostaglandin E formation in the bone and spongiosa density. 1988 Biomed. Biochim. Acta pmid:3248114
Rey HG et al. Two-sided functional Na,K-ATPase-liposomes for characterizing the permeability and side of action of pump inhibitors. 1988 Prog. Clin. Biol. Res. pmid:2906133
De Deckere EA et al. Effects of type and amount of dietary fat on rabbit and rat lymphocyte proliferation in vitro. 1988 J. Nutr. pmid:3257261
Perez RV et al. Dietary immunoregulation of transfusion-induced immunosuppression. 1988 Transplantation pmid:3258077
Tiwari RK et al. Influence of genotype on the phospholipid fatty acid composition of splenic T and B lymphocytes in MRL/MpJ-lpr/lpr mice. 1988 Immunol. Lett. pmid:3258845
Singh B et al. Effect of high/low dietary linoleic acid levels on the function and fatty acid composition of T-lymphocytes of normal and diabetic rats. 1988 Diabetes Res. pmid:3265900
Dietary fat and insulin receptor function in rat adipocytes. 1988 Nutr. Rev. pmid:3277091
Bartels T et al. [Effect of linoleic acid in food on spongioid bone density and prostaglandin biosynthesis in bones]. 1988 Beitr Orthop Traumatol pmid:3228436
Whitehead CC and Herron KM Fatty acid requirements of breeding turkeys. 1988 Br. Poult. Sci. pmid:3233502
Parsons HG et al. Supplemental calories improve essential fatty acid deficiency in cystic fibrosis patients. 1988 Pediatr. Res. pmid:3211621
Solakivi T et al. Plasma apolipoprotein B in middle-aged Finnish men. Evidence for a regional gradient of apo B and lack of negative correlation between apo B and dietary linoleate in hyperapobetalipoproteinemia. 1988 Atherosclerosis pmid:3214459
Schächtele C et al. Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine. 1988 Biochem. Biophys. Res. Commun. pmid:2831891
Loesberg C et al. Superoxide anion production by alveolar macrophages of guinea pigs fed different diets in a model of atopy. 1988 Agents Actions pmid:2833083
Garg ML et al. Differential effects of dietary linoleic and alpha-linolenic acid on lipid metabolism in rat tissues. 1988 Lipids pmid:2903427
Choi YS and Sugano M Effects of dietary alpha- and gamma-linolenic acid on lipid metabolism in young and adult rats. 1988 Ann. Nutr. Metab. pmid:2903713
Manku MS et al. Changes in human plasma essential fatty acid levels as a result of administration of linoleic acid and gamma-linolenic acid. 1988 Eur J Clin Nutr pmid:2836190
Venkatraman JT and Clandinin MT Ribonucleic acid efflux from isolated mouse liver nuclei is altered by diet and genotypically determined change in nuclear envelope composition. 1988 Biochim. Biophys. Acta pmid:2452656
MacKenzie LW et al. Prostacyclin biosynthesis by cultured human myometrial smooth muscle cells: dependency on arachidonic or linoleic acid in the culture medium. 1988 Am. J. Obstet. Gynecol. pmid:3144917
Wooten MW and Wrenn RW Linoleic acid is a potent activator of protein kinase C type III-alpha isoform in pancreatic acinar cells; its role in amylase secretion. 1988 Biochem. Biophys. Res. Commun. pmid:2454109
Benadé AJ et al. Plasma low density lipoprotein composition in relation to atherosclerosis in nutritionally defined Vervet monkeys. 1988 Atherosclerosis pmid:3145748
Salafsky B et al. Schistosoma mansoni: analysis of cercarial transformation methods. 1988 Exp. Parasitol. pmid:2458958
Hashimoto A et al. Effect of the dietary alpha-linolenate/linoleate balance on leukotriene production and histamine release in rats. 1988 Prostaglandins pmid:2459732
Bakalova RA et al. [A mechanism of the inhibitory effect of alpha-tocopherol and its synthetic analogs on the oxidation of linoleic acid catalyzed by lipoxygenase from reticulocytes]. 1988 Dokl. Akad. Nauk SSSR pmid:3135162
MacGilchrist AJ et al. Abetalipoproteinaemia in adults: role of vitamin therapy. 1988 J. Inherit. Metab. Dis. pmid:3139930
Innis SM and Yuen DE Microsomal desaturation-elongation of linoleic acid following parenteral feeding with lipid emulsions in the rat. 1988 Lipids pmid:3139951
Garg ML et al. Fish oil reduces cholesterol and arachidonic acid content more efficiently in rats fed diets containing low linoleic acid to saturated fatty acid ratios. 1988 Biochim. Biophys. Acta pmid:2844278
Grant HW et al. Dietary linoleic acid, gastric acid, and prostaglandin secretion. 1988 Gastroenterology pmid:3162220
Schepp W et al. Modulation of rat gastric mucosal prostaglandin E2 release by dietary linoleic acid: effects on gastric acid secretion and stress-induced mucosal damage. 1988 Gastroenterology pmid:3163660
Wright JR et al. Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3045812
Galli C Metabolic aspects of the biological roles of omega 3 fatty acids. 1988 Bibl Nutr Dieta pmid:3060104
Handelman GJ et al. Biopsy method for human adipose with vitamin E and lipid measurements. 1988 Lipids pmid:3172989
Palmblad J and Gyllenhammar H Effect of dietary lipids on immunity and inflammation. Review article. 1988 APMIS pmid:2841953
Albro PW et al. Comparison of the effects of carbon tetrachloride and of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the disposition of linoleic acid in rat liver in vitro. 1988 Chem. Biol. Interact. pmid:3135123
Craven PA and DeRubertis FR Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation by unsaturated fatty acids. 1988 Gastroenterology pmid:3135225
Nakagawa Y and Waku K Selective inhibition of free arachidonic acid production in activated alveolar macrophages by calmodulin antagonists. 1988 Biochem. Biophys. Res. Commun. pmid:3142466
Rafael J et al. Effect of dietary linoleic acid and essential fatty acid deficiency on resting metabolism, nonshivering thermogenesis and brown adipose tissue in the rat. 1988 J. Nutr. pmid:3367242
Simpson LO The etiopathogenesis of premenstrual syndrome as a consequence of altered blood rheology: a new hypothesis. 1988 Med. Hypotheses pmid:3367811
Behrends W et al. The glyoxysomal beta-oxidation system in cucumber seedlings: identification of enzymes required for the degradation of unsaturated fatty acids. 1988 Arch. Biochem. Biophys. pmid:3369861
Lindström P and Palmblad J Dietary linoleic acid and rat neutrophil adhesion and chemotaxis. 1988 J Clin Lab Immunol pmid:3373519
Pschera H et al. The influence of copper intrauterine device on fatty acid composition of cervical mucus lecithin. 1988 Contraception pmid:3168451
Schauder P et al. [The effect of free fatty acids on the leucine oxidation of human lymphocytes]. 1988 Beitr Infusionther Klin Ernahr pmid:3377747
Casteels M et al. Inhibition of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid oxidation and of bile acid secretion in rat liver by fatty acids. 1988 J. Biol. Chem. pmid:3350807
Kato K et al. Studies on scavengers of active oxygen species. 1. Synthesis and biological activity of 2-O-alkylascorbic acids. 1988 J. Med. Chem. pmid:3351858
Mooradian AD et al. Effect of free fatty acids on the bioavailability of plasma testosterone and dihydrotestosterone. 1988 J. Steroid Biochem. pmid:3357342
Simpson LO Unsaturated fatty acids. 1988 N. Z. Med. J. pmid:3357629
Shasby DM et al. Oxidants and conductance of cultured epithelial cell monolayers: inositol phospholipid hydrolysis. 1988 Am. J. Physiol. pmid:3144179
Crandall DL et al. Effect of varying concentrations of linoleic acid on alpha-adrenoceptor responses in spontaneously hypertensive rats. 1988 Prostaglandins Leukot. Essent. Fatty Acids pmid:2845438
Norman A et al. Postirradiation protection of chromosomes by linoleate. 1988 Int. J. Radiat. Biol. pmid:2902149
Hoffmann P et al. Investigations on the mechanism of a diminished inotropic isoprenaline effect in isolated rat hearts after high linoleic acid diet. 1988 Biomed. Biochim. Acta pmid:2854732
Spector R Fatty acid transport through the blood-brain barrier. 1988 J. Neurochem. pmid:3335863
Das UN Effect of phorbolmyristate acetate on fatty acid uptake and distribution in human promyelocytic leukemia (HL-60) cells in vitro. 1988 Biochem. Biophys. Res. Commun. pmid:3144272
Reynolds CH Inactivation of soybean lipoxygenase by lipoxygenase inhibitors in the presence of 15-hydroperoxyeicosatetraenoic acid. 1988 Biochem. Pharmacol. pmid:3144281
Chander A and Fisher AB Choline-phosphate cytidyltransferase activity and phosphatidylcholine synthesis in rat granular pneumocytes are increased with exogenous fatty acids. 1988 Biochim. Biophys. Acta pmid:2893643
Bordet JC et al. Hydroperoxides produced by n-6 lipoxygenation of arachidonic and linoleic acids potentiate synthesis of prostacyclin related compounds. 1988 Biochim. Biophys. Acta pmid:3124885
Fukuzawa K et al. Site-specific induction of lipid peroxidation by iron in charged micelles. 1988 Arch. Biochem. Biophys. pmid:2829725
Markov KhM et al. [Effect of dietary linoleic acid on the platelet aggregation, fatty acid composition of platelet phospholipids and synthesis of platelet prostaglandins in rats]. 1988 Jul-Aug Vopr. Med. Khim. pmid:3195130
Ghisolfi J et al. Metabolic utilization of linoleic acid from fat emulsion in infants during total parenteral nutrition. 1988 Jul-Aug JPEN J Parenter Enteral Nutr pmid:3138449
Cotter R et al. Fatty acid profiles in response to soybean oil lipid emulsion infusions in essential fatty acid-deficient miniature swine. 1988 Mar-Apr JPEN J Parenter Enteral Nutr pmid:3129587
Markov KhM and Kucherenko AG [Effect of diets with various contents of linoleic acid on the prostaglandin system in the rat kidney]. 1988 Mar-Apr Vopr. Med. Khim. pmid:3400199
Clark RM Lack of correlation between changes in the concentrations of linoleate and arachidonate in human milk relative to total milk lipid. 1988 Nov-Dec J. Pediatr. Gastroenterol. Nutr. pmid:3143822
Booker ML et al. Effect of dietary cholesterol on phosphatidylcholines and phosphatidylethanolamines in bile and gallbladder mucosa in the prairie dog. 1989 Gastroenterology pmid:2507386
Glatz JF et al. Fatty acid composition of serum cholesteryl esters and erythrocyte membranes as indicators of linoleic acid intake in man. 1989 Am. J. Clin. Nutr. pmid:2916448
Bernbäck S et al. Fatty acids generated by gastric lipase promote human milk triacylglycerol digestion by pancreatic colipase-dependent lipase. 1989 Biochim. Biophys. Acta pmid:2917153
Hubbard NE and Erickson KL Effect of dietary linoleic acid level on lodgement, proliferation and survival of mammary tumor metastases. 1989 Cancer Lett. pmid:2920371
Tchervenkov JI et al. The effect of donor-specific blood transfusion, cyclosporine, and dietary prostaglandin precursors on rat cardiac allograft survival. II. Effectiveness of a 24-hour induction period with DST and CsA in inducing long-term graft survival. 1989 Transplantation pmid:2643225
Balakrishnan A et al. Differential proliferative response to linoleate in cultures of epithelial cells from normal human breast and fibroadenomas. 1989 Cancer Res. pmid:2643465
Pitkänen OM et al. Determination of ethane and pentane in free oxygen radical-induced lipid peroxidation. 1989 Lipids pmid:2569148
Mertes N et al. [Experiences with a new fat emulsion in surgical intensive care medicine]. 1989 Infusionstherapie pmid:2569450
Bourre JM et al. The effects of dietary alpha-linolenic acid on the composition of nerve membranes, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. 1989 J. Nutr. pmid:2576038
Fujiyama-Fujiwara Y et al. Metabolism of gamma-linolenic acid in primary cultures of rat hepatocytes and in Hep G2 cells. 1989 J. Nutr. Sci. Vitaminol. pmid:2576804
Kihata M [Effects of exogenous insulin on oxidation of glucose and fatty acid in septic rats]. 1989 Nihon Geka Gakkai Zasshi pmid:2668730
Perez RV et al. Augmentation of donor-specific transfusion and cyclosporine effects with dietary linoleic acid. 1989 Transplantation pmid:2660353
Fairbank J et al. Octadeca-9,11-dienoic acid in cervical intraepithelial neoplasia: a colposcopic study. 1989 Clin. Chim. Acta pmid:2612010
Park JH et al. Effects of dietary linoleic acid on mucosal adaptation after small bowel resection. 1989 Digestion pmid:2612750
Hiramatsu N et al. Effects of dietary pantethine levels on drug-metabolizing system in the liver of rats orally administered varying amounts of autoxidized linoleate. 1989 J. Nutr. Sci. Vitaminol. pmid:2585150
Chanussot B et al. Liver microsomal delta 6 and delta 5 linoleic acid desaturation in female BB rats. 1989 Diabetologia pmid:2591647
Clouet P et al. Pathway of alpha-linolenic acid through the mitochondrial outer membrane in the rat liver and influence on the rate of oxidation. Comparison with linoleic and oleic acids. 1989 Biochem. J. pmid:2597132
Grossi IM et al. Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid. 1989 Cancer Res. pmid:2492204
Gardner HW Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism. 1989 Biochim. Biophys. Acta pmid:2492826
Anderson GJ and Connor WE On the demonstration of omega-3 essential-fatty-acid deficiency in humans. 1989 Am. J. Clin. Nutr. pmid:2494878
Byczkowski JZ and Kulkarni AP Lipoxygenase-catalyzed epoxidation of benzo(a)pyrene-7,8-dihydrodiol. 1989 Biochem. Biophys. Res. Commun. pmid:2494999
Kaduce TL et al. Formation of 9-hydroxyoctadecadienoic acid from linoleic acid in endothelial cells. 1989 J. Biol. Chem. pmid:2496121
Furth EE et al. The effect of endogenous essential and nonessential fatty acids on the uptake and subsequent agonist-induced release of arachidonate. 1989 J. Biol. Chem. pmid:2553711
Hansen O Characterization of fatty acid interaction with ouabain and vanadate binding to (Na+ + K+)-activated ATPase. 1989 Biochim. Biophys. Acta pmid:2554979
Hrelia S et al. Age-related changes in linoleate and alpha-linolenate desaturation by rat liver microsomes. 1989 Biochem. Biophys. Res. Commun. pmid:2570573
el Ashry A et al. The effect of dietary linoleic acid on blood pressure and erythrocyte sodium transport. 1989 J Hum Hypertens pmid:2724276
Stein O et al. Modification of cellular fatty acid composition of Hep-G2 cells: effect of antioxidants on cholesterol esterification and secretion. 1989 Biochim. Biophys. Acta pmid:2730885
Reinaud O et al. Oxidative metabolism of linoleic acid by human leukocytes. 1989 Biochem. Biophys. Res. Commun. pmid:2735926
Cunnane SC et al. Essential fatty acid and lipid profiles in plasma and erythrocytes in patients with multiple sclerosis. 1989 Am. J. Clin. Nutr. pmid:2801584
Rose DP and Connolly JM Stimulation of growth of human breast cancer cell lines in culture by linoleic acid. 1989 Biochem. Biophys. Res. Commun. pmid:2803300
Mahfouz MM et al. Changes of linoleic acid metabolism and cellular phospholipid fatty acid composition in LLC-PK cells cultured at low magnesium concentrations. 1989 Biochim. Biophys. Acta pmid:2804072
Chen Q et al. Hydrolysis of triacylglycerol arachidonic and linoleic acid ester bonds by human pancreatic lipase and carboxyl ester lipase. 1989 Biochim. Biophys. Acta pmid:2503032
Chapkin RS et al. Linoleic acid metabolism in metastatic and nonmetastatic murine mammary tumor cells. 1989 Cancer Res. pmid:2503244
Schneider YJ Optimisation of hybridoma cell growth and monoclonal antibody secretion in a chemically defined, serum- and protein-free culture medium. 1989 J. Immunol. Methods pmid:2644356
Watkins BA Influences of biotin deficiency and dietary trans-fatty acids on tissue lipids in chickens. 1989 Br. J. Nutr. pmid:2923859