Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Jones R et al. Monitoring changes in the blood of patients with multiple sclerosis. 1983 Prog. Brain Res. pmid:6665128
Champe SP et al. Sexual sporulation. 1994 Prog Ind Microbiol pmid:7765136
Johnston DV and Marshall LA Dietary fat, prostaglandins and the immune response. 1984 Prog Food Nutr Sci pmid:6091179
REISER R Conjugated linoleic acid in rat tissue lipids after ingestion as free acid and as triglyceride. 1950 Proc. Soc. Exp. Biol. Med. pmid:14781143
STEIN O and STEIN Y FATTY ACID METABOLISM BY IN VIVO LABELED ADIPOSE TISSUE IN ESSENTIAL FATTY ACID DEFICIENT RATS. 1965 Proc. Soc. Exp. Biol. Med. pmid:14264515
SWELL L et al. ESTERIFICATION OF CHOLESTEROL BY CANINE ADRENAL CELL FRACTIONS. 1965 Proc. Soc. Exp. Biol. Med. pmid:14297887
Watkins BA et al. Linoleate impairs collagen synthesis in primary cultures of avian chondrocytes. 1996 Proc. Soc. Exp. Biol. Med. pmid:8650253
KRITCHEVSKY D and TEPPER SA AUTOXIDATION OF METHYL LINOLEATE: EFFECT OF SEX HORMONES AND OF NICOTINIC ACID AND RELATED COMPOUNDS. 1964 Proc. Soc. Exp. Biol. Med. pmid:14155843
WALKER BL and KUMMEROW FA ERYTHROCYTE FATTY ACID COMPOSITION AND APPARENT PERMEABILITY TO NON-ELECTROLYTES. 1964 Proc. Soc. Exp. Biol. Med. pmid:14166569
TUREEN LL et al. EFFECT OF HIGH LINOLEIC ACID AND ANTIOXIDANT DEFICIENT DIET ON BLOOD SERUM PROTEINS IN CHICKS. 1964 Proc. Soc. Exp. Biol. Med. pmid:14121629
DESAI ID et al. PEROXIDATION AND LYSOSOMES IN NUTRITIONAL MUSCULAR DYSTROPHY OF CHICKS. 1964 Proc. Soc. Exp. Biol. Med. pmid:14121639
HOPKINS DT et al. A RESPIRATORY DISEASE SYNDROME IN CHICKENS FED ESSENTIAL FATTY ACID DEFICIENT DIETS. 1963 Proc. Soc. Exp. Biol. Med. pmid:14076921
SWELL L et al. Influence of a family diet pattern high in linoleic acid on serum cholesterol level: one year study. 1962 Proc. Soc. Exp. Biol. Med. pmid:13979681
HOLMAN RT Metabolism of isomers of linoleic and linolenic acids. 1951 Proc. Soc. Exp. Biol. Med. pmid:14816402
GORDON S and MEAD JF CONVERSION OF LINOLEIC-1-C14 ACID TO ARACHIDONIC ACID IN THE GERBIL. 1964 Proc. Soc. Exp. Biol. Med. pmid:14194646
Izumi Y et al. Effects of dietary linoleic acid on blood pressure and renal function in subtotally nephrectomized rats. 1986 Proc. Soc. Exp. Biol. Med. pmid:3532127
Wieland E et al. Peroxidase-dependent metal-independent oxidation of low density lipoprotein in vitro: a model for in vivo oxidation? 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8327462
Levay-Young BK et al. Linoleic acid, but not cortisol, stimulates accumulation of casein by mouse mammary epithelial cells in serum-free collagen gel culture. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:3317407
Yehuda S and Carasso RL Modulation of learning, pain thresholds, and thermoregulation in the rat by preparations of free purified alpha-linolenic and linoleic acids: determination of the optimal omega 3-to-omega 6 ratio. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:7901853
Baker PR et al. Red cell membrane and plasma linoleic acid nitration products: synthesis, clinical identification, and quantitation. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15273286
Whittle EJ et al. Revealing the catalytic potential of an acyl-ACP desaturase: tandem selective oxidation of saturated fatty acids. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18796606
Jiang Q et al. gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15596715
Asaoka Y et al. Potential role of phospholipase A2 in HL-60 cell differentiation to macrophages induced by protein kinase C activation. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8099446
Saeki K et al. Functional expression of a Delta12 fatty acid desaturase gene from spinach in transgenic pigs. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15067141
Kliewer SA et al. Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8041794
Chu S et al. Transformation of mammalian cells by overexpressing H2O2-generating peroxisomal fatty acyl-CoA oxidase. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7624373
Wright JR et al. Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3045812
Newman MJ Inhibition of carcinoma and melanoma cell growth by type 1 transforming growth factor beta is dependent on the presence of polyunsaturated fatty acids. 1990 Proc. Natl. Acad. Sci. U.S.A. pmid:2371287
Kang JX et al. Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7732020
Stocker R et al. Antioxidant activity of albumin-bound bilirubin. 1987 Proc. Natl. Acad. Sci. U.S.A. pmid:3475708
Hill EG et al. Perturbation of the metabolism of essential fatty acids by dietary partially hydrogenated vegetable oil. 1982 Proc. Natl. Acad. Sci. U.S.A. pmid:6951178
Lange LG Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase. 1982 Proc. Natl. Acad. Sci. U.S.A. pmid:6955782
Keler T et al. Specific growth stimulation by linoleic acid in hepatoma cell lines transfected with the target protein of a liver carcinogen. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1594582
Blaul B and Ruther J How parasitoid females produce sexy sons: a causal link between oviposition preference, dietary lipids and mate choice in Nasonia. 2011 Proc. Biol. Sci. pmid:21429922
Utermohlen V and Tucker MA Possible effects of dietary n-6 series polyunsaturated fatty acids on the development of immune dysfunction and infection. 1986 Proc Nutr Soc pmid:3797410
Betteridge J Nutrition and platelet function in atherogenesis. 1987 Proc Nutr Soc pmid:2893383
Permiakova MD and Trufanov VA [Effect of soybean lipoxygenae on baking properties of wheat flour]. 2011 May-Jun Prikl. Biokhim. Mikrobiol. pmid:21790037
Dupont J Essential fatty acids and prostaglandins. 1987 Prev Med pmid:3628199
Cohen LA Fat and endocrine-responsive cancer in animals. 1987 Prev Med pmid:3476922
WAREMBOURG H et al. [COMPARATIVE STUDY OF THE LIPID COMPOSITION OF THE PLASMA IN THE HEALTHY SUBJECT AND IN SIMPLE AND COMPLICATED DIABETES]. 1964 Presse Med pmid:14214759
Wadekar SD et al. Microbial synthesis of rhamnolipids by Pseudomonas aeruginosa (ATCC 10145) on waste frying oil as low cost carbon source. 2012 Prep. Biochem. Biotechnol. pmid:22509850
TORRES LM and VOROBIOFF S [TREATMENT OF CIRRHOSIS]. 1963 Prensa Med Argent pmid:14091581
DUDAN A [Essential polyunsaturated fatty acids; clinical study and therapeutic indications]. 1956 Praxis pmid:13335660
Du M et al. Effects of dietary conjugated linoleic acid and linoleic:linolenic acid ratio on polyunsaturated fatty acid status in laying hens. 2000 Poult. Sci. pmid:11194037
Badinga L et al. Dietary conjugated linoleic acid alters hepatic lipid content and fatty acid composition in broiler chickens. 2003 Poult. Sci. pmid:12580252
Ferrini G et al. Dietary polyunsaturated fat reduces skin fat as well as abdominal fat in broiler chickens. 2008 Poult. Sci. pmid:18281580
Ain Baziz H et al. Chronic heat exposure enhances fat deposition and modifies muscle and fat partition in broiler carcasses. 1996 Poult. Sci. pmid:8786940
Wang YW et al. Maternal dietary ratio of linoleic acid to alpha-linolenic acid affects the passive immunity of hatching chicks. 2004 Poult. Sci. pmid:15615018
Du M et al. Quality characteristics of irradiated ready-to-eat breast rolls from turkeys fed conjugated linoleic acid. 2002 Poult. Sci. pmid:12269620
Ahn DU et al. Effect of dietary conjugated linoleic acid on the quality characteristics of chicken eggs during refrigerated storage. 1999 Poult. Sci. pmid:10438141