Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Takahashi T et al. Effect of linoleic acid albumin in a dilution solution and long-term equilibration for freezing of bovine spermatozoa with poor freezability. 2012 Reprod. Domest. Anim. pmid:21635578
Kiernan M et al. The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. 2013 Reprod. Fertil. Dev. pmid:23036717
Marei WF et al. Differential effects of linoleic and alpha-linolenic fatty acids on spatial and temporal mitochondrial distribution and activity in bovine oocytes. 2012 Reprod. Fertil. Dev. pmid:22697118
Van Nevel CJ and Demeyer DI Influence of pH on lipolysis and biohydrogenation of soybean oil by rumen contents in vitro. 1996 Reprod. Nutr. Dev. pmid:8881592
Joffre F et al. In vivo oxidation of carboxyl-labelled cyclic fatty acids formed from linoleic and linolenic acids in the rat. 2004 Mar-Apr Reprod. Nutr. Dev. pmid:15270550
Mourot J et al. [Effects of dietary linoleic acid on lipogenesis enzyme activity in adipose tissue in the pig]. 1994 Reprod. Nutr. Dev. pmid:7914083
Kouba M and Mourot J Effect of a high linoleic acid diet on delta 9-desaturase activity, lipogenesis and lipid composition of pig subcutaneous adipose tissue. 1998 Jan-Feb Reprod. Nutr. Dev. pmid:9606747
Farnworth ER and Kramer JK Fat supplementation to the gestation diet of older sows and its effect on maternal and fetal fat metabolism. 1990 Reprod. Nutr. Dev. pmid:1981311
Christon R et al. Effects of a low dietary linoleic acid level on intestinal morphology and enterocyte brush border membrane lipid composition. 1991 Reprod. Nutr. Dev. pmid:1777061
Troegeler-Meynadier A et al. Rates and efficiencies of reactions of ruminal biohydrogenation of linoleic acid according to pH and polyunsaturated fatty acids concentrations. 2006 Nov-Dec Reprod. Nutr. Dev. pmid:17169317
Castellanos P et al. Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. 2010 Reprod. Toxicol. pmid:20096347
Joseph P et al. Bioactivation of benzo(a)pyrene-7,8-dihydrodiol catalyzed by lipoxygenase purified from human term placenta and conceptal tissues. 1994 Jul-Aug Reprod. Toxicol. pmid:7949756
Kim JY et al. Lipid and fatty acid analysis of fresh and frozen-thawed immature and in vitro matured bovine oocytes. 2001 Reproduction pmid:11425337
Zachut M et al. Dietary unsaturated fatty acids influence preovulatory follicle characteristics in dairy cows. 2008 Reproduction pmid:18296508
Robinson RS et al. Effects of dietary polyunsaturated fatty acids on ovarian and uterine function in lactating dairy cows. 2002 Reproduction pmid:12090925
Marei WF et al. Impact of linoleic acid on bovine oocyte maturation and embryo development. 2010 Reproduction pmid:20215338
Adam O et al. Prostaglandin formation and platelet aggregation during fasting and linoleic acid intake. 1985 Res Exp Med (Berl) pmid:3992060
McCarthy-Beckett DO Dietary supplementation with conjugated linoleic acid does not improve nutritional status of tumor-bearing rats. 2002 Res Nurs Health pmid:11807919
Kulkarni AP and Cook DC Hydroperoxidase activity of lipoxygenase: a potential pathway for xenobiotic metabolism in the presence of linoleic acid. 1988 Res. Commun. Chem. Pathol. Pharmacol. pmid:3141996
Bayorh MA et al. Acute and chronic effects of eicosapentaenoic acid (EPA) on the cardiovascular system. 1989 Res. Commun. Chem. Pathol. Pharmacol. pmid:2558405