Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Netsu S et al. | Oral eicosapentaenoic acid supplementation as possible therapy for endometriosis. | 2008 | Fertil. Steril. | pmid:18054352 |
| Diniz YS et al. | Conjugated linoleic acid and cardiac health: oxidative stress and energetic metabolism in standard and sucrose-rich diets. | 2008 | Eur. J. Pharmacol. | pmid:18054909 |
| Ogata K et al. | Dosage plan of a flurbiprofen injection product using inhibition of protein binding by lipid emulsion in rats. | 2008 | J. Pharm. Pharmacol. | pmid:18088500 |
| Lei Q and Boatright WL | Lipoxygenase independent hexanal formation in isolated soy proteins induced by reducing agents. | 2008 | J. Food Sci. | pmid:19241535 |
| Pandey NR et al. | Linoleic acid-enriched phospholipids act through peroxisome proliferator-activated receptors alpha to stimulate hepatic apolipoprotein A-I secretion. | 2008 | Biochemistry | pmid:18189424 |
| Koszelak-Rosenblum M et al. | His-311 and Arg-559 are key residues involved in fatty acid oxygenation in pathogen-inducible oxygenase. | 2008 | J. Biol. Chem. | pmid:18596034 |
| Frenette M and Scaiano JC | Evidence for hydroxyl radical generation during lipid (linoleate) peroxidation. | 2008 | J. Am. Chem. Soc. | pmid:18597469 |
| Pinnick KE et al. | Pancreatic ectopic fat is characterized by adipocyte infiltration and altered lipid composition. | 2008 | Obesity (Silver Spring) | pmid:18239594 |
| Eder E et al. | Lipid peroxidation-related 1,N2-propanodeoxyguanosine-DNA adducts induced by endogenously formed 4-hydroxy-2-nonenal in organs of female rats fed diets supplemented with sunflower, rapeseed, olive or coconut oil. | 2008 | Mutat. Res. | pmid:18602860 |
| Li Y et al. | Molecular recognition of nitrated fatty acids by PPAR gamma. | 2008 | Nat. Struct. Mol. Biol. | pmid:18604218 |
| Kuiper HC et al. | Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress. | 2008 | J. Biol. Chem. | pmid:18442969 |
| Ohmori H et al. | Linoleic-acid-induced growth suppression induces quiescent cancer cell nests in nude mice. | 2008 | Pathobiology | pmid:18580068 |
| Xin HL et al. | [Alpha-linolenic acid and linoleic acid in extract of Portulaca oleracea L. determined by high-performance liquid chromatography]. | 2008 | Zhong Xi Yi Jie He Xue Bao | pmid:18990345 |
| Meguid NA et al. | Role of polyunsaturated fatty acids in the management of Egyptian children with autism. | 2008 | Clin. Biochem. | pmid:18582451 |
| Garscha U and Oliw E | Pichia expression and mutagenesis of 7,8-linoleate diol synthase change the dioxygenase and hydroperoxide isomerase. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18586008 |
| Rhayem Y et al. | Chain-breaking activity of resveratrol and piceatannol in a linoleate micellar model. | 2008 | Chem. Phys. Lipids | pmid:18590713 |
| Wang L et al. | The role of fatty acids and caveolin-1 in tumor necrosis factor alpha-induced endothelial cell activation. | 2008 | Metab. Clin. Exp. | pmid:18803934 |
| Wejnerowska G et al. | Determination of linoleic acid in toothpaste by gas chromatography with flame ionization detection. | 2008 | Anal Sci | pmid:18544865 |
| Morishita M et al. | Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion. | 2008 | J Control Release | pmid:18804128 |
| Iqbal MJ et al. | A combination of CLA-DAG oil modifies the diabetic phenotype in male Zucker diabetic fatty rats. | 2008 | Horm. Metab. Res. | pmid:18548385 |
| Zhao YF et al. | Activation of ATP-sensitive potassium channels in rat pancreatic beta-cells by linoleic acid through both intracellular metabolites and membrane receptor signalling pathway. | 2008 | J. Endocrinol. | pmid:18550787 |
| Still K et al. | The peroxisome proliferator activator receptor alpha/delta agonists linoleic acid and bezafibrate upregulate osteoblast differentiation and induce periosteal bone formation in vivo. | 2008 | Calcif. Tissue Int. | pmid:18836674 |
| Burenjargal M and Totani N | Effects of thermally processed oil on weight loss in rats. | 2008 | J Oleo Sci | pmid:18685228 |
| Martinelli N et al. | FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. | 2008 | Am. J. Clin. Nutr. | pmid:18842780 |
| Saez G et al. | Is the hepatic metabolism of glucose and linoleic acid influenced by species in overfed ducks? | 2008 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:18687407 |
| Suh HN et al. | Linoleic acid stimulates gluconeogenesis via Ca2+/PLC, cPLA2, and PPAR pathways through GPR40 in primary cultured chicken hepatocytes. | 2008 | Am. J. Physiol., Cell Physiol. | pmid:18842827 |
| Rahuman AA et al. | Mosquito larvicidal activity of oleic and linoleic acids isolated from Citrullus colocynthis (Linn.) Schrad. | 2008 | Parasitol. Res. | pmid:18688644 |
| Wang J et al. | 5-lipoxygenase and 5-lipoxygenase-activating protein gene polymorphisms, dietary linoleic acid, and risk for breast cancer. | 2008 | Cancer Epidemiol. Biomarkers Prev. | pmid:18843019 |
| Luna P et al. | Gas chromatography and silver-ion high-performance liquid chromatography analysis of conjugated linoleic acid isomers in free fatty acid form using sulphuric acid in methanol as catalyst. | 2008 | J Chromatogr A | pmid:18692191 |
| Miura K et al. | Relationship of dietary linoleic acid to blood pressure. The International Study of Macro-Micronutrients and Blood Pressure Study [corrected]. | 2008 | Hypertension | pmid:18606902 |
| Damsgaard CT et al. | Fish oil in combination with high or low intakes of linoleic acid lowers plasma triacylglycerols but does not affect other cardiovascular risk markers in healthy men. | 2008 | J. Nutr. | pmid:18492834 |
| Ogorodnikova AV et al. | Detection of divinyl ether synthase in Lily-of-the-Valley (Convallaria majalis) roots. | 2008 | Phytochemistry | pmid:18952245 |
| Williams M and Harwood JL | Characterisation of lipoxygenase isoforms from olive callus cultures. | 2008 | Phytochemistry | pmid:18790508 |
| Methy N et al. | Dietary fatty acids and recurrence of colorectal adenomas in a European intervention trial. | 2008 | Nutr Cancer | pmid:18791918 |
| Jacquot C et al. | Kinetic isotope effects in the oxidation of arachidonic acid by soybean lipoxygenase-1. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18793849 |
| Maeda H et al. | Tocopherols modulate extraplastidic polyunsaturated fatty acid metabolism in Arabidopsis at low temperature. | 2008 | Plant Cell | pmid:18314499 |
| Gülçin I | In vitro prooxidant effect of caffeine. | 2008 | J Enzyme Inhib Med Chem | pmid:18341268 |
| Minami Y et al. | Occurrence of singlet oxygen oxygenation of oleic acid and linoleic acid in the skin of live mice. | 2008 | Free Radic. Res. | pmid:18344113 |
| Zachut M et al. | Dietary unsaturated fatty acids influence preovulatory follicle characteristics in dairy cows. | 2008 | Reproduction | pmid:18296508 |
| Horowitz Brown S et al. | Morphological transitions governed by density dependence and lipoxygenase activity in Aspergillus flavus. | 2008 | Appl. Environ. Microbiol. | pmid:18658287 |
| Ashby RD et al. | Property control of sophorolipids: influence of fatty acid substrate and blending. | 2008 | Biotechnol. Lett. | pmid:18264681 |
| Zhu H et al. | 15-lipoxygenase-1 activates tumor suppressor p53 independent of enzymatic activity. | 2008 | Int. J. Cancer | pmid:18785202 |
| Ringseis R et al. | Conjugated linoleic acid isomers inhibit platelet-derived growth factor-induced NF-kappaB transactivation and collagen formation in human vascular smooth muscle cells. | 2008 | Eur J Nutr | pmid:18264811 |
| Fang KM et al. | Free fatty acids act as endogenous ionophores, resulting in Na+ and Ca2+ influx and myocyte apoptosis. | 2008 | Cardiovasc. Res. | pmid:18267958 |
| Kishino T et al. | Visceral fat thickness in overweight men correlates with alterations in serum fatty acid composition. | 2008 | Clin. Chim. Acta | pmid:18771663 |
| Rashid S et al. | Topical omega-3 and omega-6 fatty acids for treatment of dry eye. | 2008 | Arch. Ophthalmol. | pmid:18268213 |
| Jones PJ et al. | The effect of dietary oleic, linoleic, and linolenic acids on fat oxidation and energy expenditure in healthy men. | 2008 | Metab. Clin. Exp. | pmid:18702944 |
| Hofmann E and Pollmann S | Molecular mechanism of enzymatic allene oxide cyclization in plants. | 2008 | Plant Physiol. Biochem. | pmid:18272375 |
| Dai F et al. | Antioxidant synergism of green tea polyphenols with alpha-tocopherol and L-ascorbic acid in SDS micelles. | 2008 | Biochimie | pmid:18554517 |
| Artmann A et al. | Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine. | 2008 | Biochim. Biophys. Acta | pmid:18316044 |
| McEntee MF et al. | Dietary n-3 polyunsaturated fatty acids enhance hormone ablation therapy in androgen-dependent prostate cancer. | 2008 | Am. J. Pathol. | pmid:18556778 |
| Or-Rashid MM et al. | Studies on the production of conjugated linoleic acid from linoleic and vaccenic acids by mixed rumen protozoa. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18797866 |
| Sasaki N et al. | Down-regulation of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPARalpha. | 2008 | Eur J Nutr | pmid:18320257 |
| Chicco AJ et al. | Linoleate-rich high-fat diet decreases mortality in hypertensive heart failure rats compared with lard and low-fat diets. | 2008 | Hypertension | pmid:18663155 |
| El-Yassimi A et al. | Linoleic acid induces calcium signaling, Src kinase phosphorylation, and neurotransmitter release in mouse CD36-positive gustatory cells. | 2008 | J. Biol. Chem. | pmid:18321850 |
| de Virville JD et al. | Changes in electron transport pathways in endoplasmic reticulum of rapeseed in response to cold. | 2008 | Planta | pmid:18663470 |
| Zhao ZY et al. | Influence of dietary conjugated linoleic acid on growth, fatty acid composition and hepatic lipogenesis in large yellow croaker (Pseudosciaena crocea R.). | 2008 | J Zhejiang Univ Sci B | pmid:18763301 |
| Ferrini G et al. | Dietary polyunsaturated fat reduces skin fat as well as abdominal fat in broiler chickens. | 2008 | Poult. Sci. | pmid:18281580 |
| Wang L et al. | Changing ratios of omega-6 to omega-3 fatty acids can differentially modulate polychlorinated biphenyl toxicity in endothelial cells. | 2008 | Chem. Biol. Interact. | pmid:18155686 |
| Chavarro JE et al. | A prospective study of trans-fatty acid levels in blood and risk of prostate cancer. | 2008 | Cancer Epidemiol. Biomarkers Prev. | pmid:18199715 |
| Brosnan MJ and Carkner RD | Hepatic effects of a fructose diet in the stroke-prone spontaneously hypertensive rat. | 2008 | Am. J. Hypertens. | pmid:18437120 |
| Lang I et al. | A lipoxygenase with linoleate diol synthase activity from Nostoc sp. PCC 7120. | 2008 | Biochem. J. | pmid:18031288 |
| Andersson C et al. | Cell culture models demonstrate that CFTR dysfunction leads to defective fatty acid composition and metabolism. | 2008 | J. Lipid Res. | pmid:18441018 |
| Petit HV et al. | Quality of embryos produced from dairy cows fed whole flaxseed and the success of embryo transfer. | 2008 | J. Dairy Sci. | pmid:18420609 |
| Fan X et al. | Factors affecting thermally induced furan formation. | 2008 | J. Agric. Food Chem. | pmid:18811167 |
| Caffieri S et al. | UVB photolysis of hydrocortisone 21-acetate. | 2008 | J Pharm Biomed Anal | pmid:18423938 |
| Godkin JD et al. | Phospholipase A2 regulation of bovine endometrial (BEND) cell prostaglandin production. | 2008 | Reprod. Biol. Endocrinol. | pmid:18811942 |
| Kwon JI et al. | Induction of apoptosis by linoleic acid is associated with the modulation of Bcl-2 family and Fas/FasL system and activation of caspases in AGS human gastric adenocarcinoma cells. | 2008 | J Med Food | pmid:18361731 |
| Warensjö E et al. | Effects of saturated and unsaturated fatty acids on estimated desaturase activities during a controlled dietary intervention. | 2008 | Nutr Metab Cardiovasc Dis | pmid:18367385 |
| Chung SH et al. | Synthesis of conjugated linoleic acid by human-derived Bifidobacterium breve LMC 017: utilization as a functional starter culture for milk fermentation. | 2008 | J. Agric. Food Chem. | pmid:18410112 |
| Ueda Y et al. | Elevated concentrations of linoleic acid in erythrocyte membrane phospholipids in patients with inflammatory bowel disease. | 2008 | Nutr Res | pmid:19083414 |
| Lopes PA et al. | Diet supplementation with the cis-9,trans-11 conjugated linoleic acid isomer affects the size of adipocytes in Wistar rats. | 2008 | Nutr Res | pmid:19083449 |
| Higashi-Okai K et al. | Potent antioxidant and radical-scavenging activities of traditional Japanese cereal grains. | 2008 | J. UOEH | pmid:19086696 |
| Tao M et al. | Relationship of polyunsaturated fatty acid intake to peripheral neuropathy among adults with diabetes in the National Health and Nutrition Examination Survey (NHANES) 1999 2004. | 2008 | Diabetes Care | pmid:17914029 |
| Mateu-de Antonio J et al. | Comparative effects of olive oil-based and soyabean oil-based emulsions on infection rate and leucocyte count in critically ill patients receiving parenteral nutrition. | 2008 | Br. J. Nutr. | pmid:17916276 |
| Rahman MM et al. | Docosahexaenoic acid is more potent inhibitor of osteoclast differentiation in RAW 264.7 cells than eicosapentaenoic acid. | 2008 | J. Cell. Physiol. | pmid:17929247 |
| Ku CS and Mun SP | Antioxidant activities of ethanol extracts from seeds in fresh Bokbunja (Rubus coreanus Miq.) and wine processing waste. | 2008 | Bioresour. Technol. | pmid:17931856 |
| Sarikurkcu C et al. | Studies on the antioxidant activity of the essential oil and methanol extract of Marrubium globosum subsp. globosum (lamiaceae) by three different chemical assays. | 2008 | Bioresour. Technol. | pmid:17920880 |
| Bueno AA et al. | Effects of different fatty acids and dietary lipids on adiponectin gene expression in 3T3-L1 cells and C57BL/6J mice adipose tissue. | 2008 | Pflugers Arch. | pmid:17717684 |
| Tepe B | Antioxidant potentials and rosmarinic acid levels of the methanolic extracts of Salvia virgata (Jacq), Salvia staminea (Montbret & Aucher ex Bentham) and Salvia verbenaca (L.) from Turkey. | 2008 | Bioresour. Technol. | pmid:17531471 |
| Xanthopoulou MN et al. | Biological studies of new organotin(IV) complexes of thioamide ligands. | 2008 | Eur J Med Chem | pmid:17509733 |
| Vinceti M et al. | Food intake and risk of cutaneous melanoma in an Italian population. | 2008 | Eur J Clin Nutr | pmid:17657227 |
| Damsgaard CT et al. | The effects of fish oil and high or low linoleic acid intake on fatty acid composition of human peripheral blood mononuclear cells. | 2008 | Br. J. Nutr. | pmid:17663804 |
| Chen J et al. | [Mechanism of linoleic acid on the expression of plasminogen activator inhibitor type-1 in HepG2 cells]. | 2008 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21141508 |
| Gilani GS and Nasim A | Impact of foods nutritionally enhanced through biotechnology in alleviating malnutrition in developing countries. | 2007 Sep-Oct | J AOAC Int | pmid:17955991 |
| Al-Turkmani MR et al. | Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis. | 2007 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18036797 |
| Chechetkin IR et al. | Regio- and stereospecificity of recombinant soybean lipoxygenase-2. | 2007 Jul-Aug | Dokl. Biochem. Biophys. | pmid:17933341 |
| Cho K et al. | Biochemical characterization of the dual positional specific maize lipoxygenase and the dependence of lagging and initial burst phenomenon on pH, substrate, and detergent during pre-steady state kinetics. | 2007 | J. Biochem. Mol. Biol. | pmid:17244489 |
| Muzio G et al. | PPARalpha and PP2A are involved in the proapoptotic effect of conjugated linoleic acid on human hepatoma cell line SK-HEP-1. | 2007 | Int. J. Cancer | pmid:17691108 |
| Breza JM et al. | Monosodium glutamate but not linoleic acid differentially activates gustatory neurons in the rat geniculate ganglion. | 2007 | Chem. Senses | pmid:17693416 |
| Azavache V et al. | [Is brown adipose tissue a store of long chain polyunsaturated fatty acids during postnatal developing brain?]. | 2007 | Arch Latinoam Nutr | pmid:17824193 |
| Fang IM et al. | Linoleic acid-induced expression of inducible nitric oxide synthase and cyclooxygenase II via p42/44 mitogen-activated protein kinase and nuclear factor-kappaB pathway in retinal pigment epithelial cells. | 2007 | Exp. Eye Res. | pmid:17825288 |
| Ito T et al. | The homeotic protein AGAMOUS controls late stamen development by regulating a jasmonate biosynthetic gene in Arabidopsis. | 2007 | Plant Cell | pmid:17981996 |
| Balesteros MR et al. | Determination of olive oil acidity by CE. | 2007 | Electrophoresis | pmid:17941122 |
| Tannin-Spitz T et al. | Cucurbitacin glucosides: antioxidant and free-radical scavenging activities. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17942079 |
| Barla A et al. | Screening of antioxidant activity of three Euphorbia species from Turkey. | 2007 | Fitoterapia | pmid:17582698 |
| Tejero I et al. | A PM3/d specific reaction parameterization for iron atom in the hydrogen abstraction catalyzed by soybean lipoxygenase-1. | 2007 | J Comput Chem | pmid:17274015 |
| Dufour C et al. | Inhibition of the peroxidation of linoleic acid by the flavonoid quercetin within their complex with human serum albumin. | 2007 | Free Radic. Biol. Med. | pmid:17603933 |
| Altmann R et al. | 13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells. | 2007 | Biochem. Pharmacol. | pmid:17604003 |
| Zeng YX et al. | Comparative analysis of volatile components from Clematis species growing in China. | 2007 | Anal. Chim. Acta | pmid:17606017 |