Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Thorax (1)
- Am. J. Physiol., Cell Physiol. (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Macouzet M et al. | Production of conjugated linoleic acid by probiotic Lactobacillus acidophilus La-5. | 2009 | J. Appl. Microbiol. | pmid:19228257 |
| Makyła K and Paluch M | The linoleic acid influence on molecular interactions in the model of biological membrane. | 2009 | Colloids Surf B Biointerfaces | pmid:19211229 |
| Pacini G et al. | Reappraisal of the intravenous glucose tolerance index for a simple assessment of insulin sensitivity in mice. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19211728 |
| Toyosaki T and Iwabuchi M | New antioxidant protein in seaweed (Porphyra yezoensis Ueda). | 2009 | Int J Food Sci Nutr | pmid:19212859 |
| Liavonchanka A et al. | On the mechanism of a polyunsaturated fatty acid double bond isomerase from Propionibacterium acnes. | 2009 | J. Biol. Chem. | pmid:19164287 |
| Pintore G et al. | Rosmarinus officinalis L.: chemical modifications of the essential oil and evaluation of antioxidant and antimicrobial activity. | 2009 | Nat Prod Commun | pmid:20120107 |
| Ibrahim A et al. | Impact of maternal dietary fatty acid composition on glucose and lipid metabolism in male rat offspring aged 105 d. | 2009 | Br. J. Nutr. | pmid:19166630 |
| Kawahara S et al. | Effects of dietary supplementation with conjugated linoleic acid on fatty acid composition and lipid oxidation in chicken breast meat. | 2009 | Anim. Sci. J. | pmid:20163609 |
| Calder PC | Early life programming of immune and lung function: can we now exclude a role of arachidonic acid exposure? | 2009 | Br. J. Nutr. | pmid:19166631 |
| Oku H et al. | The effects of 2-bromopalmitate on the fatty acid composition in differentiating adipocytes of red sea bream (Pagrus major). | 2009 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:19166960 |
| Schwartz J et al. | Modification of dietary polyunsaturated fatty acids via complementary food enhances n-3 long-chain polyunsaturated fatty acid synthesis in healthy infants: a double blinded randomised controlled trial. | 2009 | Arch. Dis. Child. | pmid:19193660 |
| Uygun DA et al. | A novel support for antibody purification: fatty acid attached chitosan beads. | 2009 | Colloids Surf B Biointerfaces | pmid:19196498 |
| Carlotti ME et al. | Role of particle coating in controlling skin damage photoinduced by titania nanoparticles. | 2009 | Free Radic. Res. | pmid:19199115 |
| Nasrollahzadeh J et al. | Study of in vitro and in vivo effect of docosahexaenoic acid on rat C6 glioma. | 2009 | J. Exp. Ther. Oncol. | pmid:20192116 |
| Sahoo RR and Biswas SK | Frictional response of fatty acids on steel. | 2009 | J Colloid Interface Sci | pmid:19232636 |
| MartÃnez-Force E et al. | Influence of specific fatty acids on the asymmetric distribution of saturated fatty acids in sunflower (Helianthus annuus L.) triacylglycerols. | 2009 | J. Agric. Food Chem. | pmid:19166295 |
| HÃ¥versen L et al. | Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages. | 2009 | Atherosclerosis | pmid:18599066 |
| Guillén N et al. | Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver. | 2009 | Physiol. Genomics | pmid:19258494 |
| Cho MC et al. | Optimization of an enzyme-linked immunosorbent assay to screen ligand of Peroxisome proliferator-activated receptor alpha. | 2009 | Immunopharmacol Immunotoxicol | pmid:19263263 |
| Gülçin I | Antioxidant activity of L-adrenaline: a structure-activity insight. | 2009 | Chem. Biol. Interact. | pmid:18929549 |
| Ishitsuka Y et al. | Effects of bolus injection of soybean-based fat emulsion and fatty acids on pulmonary gas exchange function. | 2009 | Biol. Pharm. Bull. | pmid:19252304 |
| Blask DE et al. | Circadian stage-dependent inhibition of human breast cancer metabolism and growth by the nocturnal melatonin signal: consequences of its disruption by light at night in rats and women. | 2009 | Integr Cancer Ther | pmid:20042410 |
| de Meijer VE et al. | Parenteral fish oil as monotherapy for patients with parenteral nutrition-associated liver disease. | 2009 | Pediatr. Surg. Int. | pmid:18828026 |
| Saitou K et al. | Contribution of gustation to the palatability of linoleic acid. | 2009 | Physiol. Behav. | pmid:18835400 |
| RodrÃguez-Cruz M et al. | Effect of dietary levels of corn oil on maternal arachidonic acid synthesis and fatty acid composition in lactating rats. | 2009 | Nutrition | pmid:18849148 |
| Bannenberg G et al. | Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana. | 2009 | Lipids | pmid:18949503 |
| Lapenna D et al. | Inhibitory activity of salicylic acid on lipoxygenase-dependent lipid peroxidation. | 2009 | Biochim. Biophys. Acta | pmid:18950686 |
| Zheng Y et al. | Role of caveolin-1 in EGCG-mediated protection against linoleic-acid-induced endothelial cell activation. | 2009 | J. Nutr. Biochem. | pmid:18656337 |
| Taha AY et al. | Dose-dependent anticonvulsant effects of linoleic and alpha-linolenic polyunsaturated fatty acids on pentylenetetrazol induced seizures in rats. | 2009 | Epilepsia | pmid:18657173 |
| Raz R et al. | The influence of short-chain essential fatty acids on children with attention-deficit/hyperactivity disorder: a double-blind placebo-controlled study. | 2009 | J Child Adolesc Psychopharmacol | pmid:19364294 |
| Nayeem F et al. | Dietary beta-tocopherol and linoleic acid, serum insulin, and waist circumference predict circulating sex hormone-binding globulin in premenopausal women. | 2009 | J. Nutr. | pmid:19339706 |
| Wang S et al. | In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation. | 2009 | Br. J. Nutr. | pmid:19660150 |
| Inoue N et al. | Linoleic acid-menthyl ester reduces the secretion of apolipoprotein B100 in HepG2 cells. | 2009 | J Oleo Sci | pmid:19282639 |
| Fukuda S et al. | Evaluation and characterization of bacterial metabolic dynamics with a novel profiling technique, real-time metabolotyping. | 2009 | PLoS ONE | pmid:19287504 |
| Santillo A et al. | Probiotic in lamb rennet paste enhances rennet lipolytic activity, and conjugated linoleic acid and linoleic acid content in Pecorino cheese. | 2009 | J. Dairy Sci. | pmid:19307614 |
| Zhang D et al. | Identification and expression of a new delta-12 fatty acid desaturase (FAD2-4) gene in upland cotton and its functional expression in yeast and Arabidopsis thaliana plants. | 2009 | Plant Physiol. Biochem. | pmid:19217793 |
| Stratford JM and Contreras RJ | Saliva and other taste stimuli are important for gustatory processing of linoleic acid. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19692663 |
| Choi NJ et al. | Characterizations of environmental factors in conjugated linoleic acid production by mixed rumen bacteria. | 2009 | J. Agric. Food Chem. | pmid:19754193 |
| Zhang B et al. | [Studies on the chemical constituents of the root and rhizoma of Ligusticum jeholense]. | 2009 | Zhong Yao Cai | pmid:19771843 |
| Chow CK | Dietary beta-tocopherol and serum concentrations of sex hormone-binding globulin. | 2009 | J. Nutr. | pmid:19710160 |
| Roche M et al. | Olive phenols efficiently inhibit the oxidation of serum albumin-bound linoleic acid and butyrylcholine esterase. | 2009 | Biochim. Biophys. Acta | pmid:19714864 |
| Pianaro A et al. | Stingless bees: chemical differences and potential functions in Nannotrigona testaceicornis and Plebeia droryana males and workers. | 2009 | J. Chem. Ecol. | pmid:19730955 |
| Jirovetz L et al. | Chemical composition, olfactory evaluation and antioxidant effects of essential oil from Mentha canadensis. | 2009 | Nat Prod Commun | pmid:19731614 |
| de Castro J et al. | Platelet linoleic acid is a potential biomarker of advanced non-small cell lung cancer. | 2009 | Exp. Mol. Pathol. | pmid:19733167 |
| Pandey NR et al. | An induction in hepatic HDL secretion associated with reduced ATPase expression. | 2009 | Am. J. Pathol. | pmid:19717637 |
| Radunz AE et al. | Effects of dietary polyunsaturated fatty acid supplementation on fatty acid composition in muscle and subcutaneous adipose tissue of lambs. | 2009 | J. Anim. Sci. | pmid:19717771 |
| Proudfoot JM et al. | HDL is the major lipoprotein carrier of plasma F2-isoprostanes. | 2009 | J. Lipid Res. | pmid:19050315 |
| Hodson L et al. | Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:18940935 |
| Li Z et al. | Synthesis and biological activity of hydroxylated derivatives of linoleic acid and conjugated linoleic acids. | 2009 | Chem. Phys. Lipids | pmid:19146841 |
| Tribole E | What happened to do no harm? The issue of dietary omega-6 fatty acids. | 2009 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19147337 |
| Ramsden CE et al. | Letter to the Editor re: Linoleic acid and coronary heart disease. Prostaglandins Leukot. Essent. Fatty Acids (2008), by W.S. Harris. | 2009 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19147338 |
| Du YZ et al. | Preparation and characteristics of linoleic acid-grafted chitosan oligosaccharide micelles as a carrier for doxorubicin. | 2009 | Colloids Surf B Biointerfaces | pmid:19131223 |
| Plaisance V et al. | Role of the transcriptional factor C/EBPbeta in free fatty acid-elicited beta-cell failure. | 2009 | Mol. Cell. Endocrinol. | pmid:19133313 |
| Lee CM et al. | SPION-loaded chitosan-linoleic acid nanoparticles to target hepatocytes. | 2009 | Int J Pharm | pmid:19138733 |
| Tan YL and Liu CG | Self-aggregated nanoparticles from linoleic acid modified carboxymethyl chitosan: Synthesis, characterization and application in vitro. | 2009 | Colloids Surf B Biointerfaces | pmid:19124228 |
| Staiger H et al. | Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. | 2009 | Diabetes | pmid:19074989 |
| Sánchez-Campillo M et al. | Rosmarinic acid, a photo-protective agent against UV and other ionizing radiations. | 2009 | Food Chem. Toxicol. | pmid:19084569 |
| Yano M et al. | Oxidative stress induces anti-hepatitis C virus status via the activation of extracellular signal-regulated kinase. | 2009 | Hepatology | pmid:19492433 |
| Tanaka N et al. | Dietary olive oil prevents carbon tetrachloride-induced hepatic fibrosis in mice. | 2009 | J. Gastroenterol. | pmid:19506795 |
| Cho CW et al. | Enhanced transdermal delivery of loratadine from the EVA matrix. | 2009 | Drug Deliv | pmid:19514983 |
| Khalili M et al. | Influence of exogenous salicylic acid on flavonolignans and lipoxygenase activity in the hairy root cultures of Silybum marianum. | 2009 | Cell Biol. Int. | pmid:19524695 |
| Damsgaard CT et al. | Reduced ex vivo interleukin-6 production by dietary fish oil is not modified by linoleic acid intake in healthy men. | 2009 | J. Nutr. | pmid:19494025 |
| Zhang M et al. | Cytotoxic aggregates of alpha-lactalbumin induced by unsaturated fatty acid induce apoptosis in tumor cells. | 2009 | Chem. Biol. Interact. | pmid:19497410 |
| Villa PM et al. | Free fatty acid profiles in preeclampsia. | 2009 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:19497719 |
| Jeng JY et al. | Linoleic acid promotes mitochondrial biogenesis and maintains mitochondrial structure for prevention of streptozotocin damage in RIN-m5F cells. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19502730 |
| Pinho RS et al. | Potential oilseed crops from the semiarid region of northeastern Brazil. | 2009 | Bioresour. Technol. | pmid:19577461 |
| Guyenet SJ | High-fat diets: details matter. | 2009 | Obesity (Silver Spring) | pmid:19553921 |
| Zhang HM et al. | Linoleic acid-induced mitochondrial Ca(2+) efflux causes peroxynitrite generation and protein nitrotyrosylation. | 2009 | PLoS ONE | pmid:19557129 |
| Sarikurkcu C et al. | Studies on the antioxidant activity of essential oil and different solvent extracts of Vitexagnuscastus L. fruits from Turkey. | 2009 | Food Chem. Toxicol. | pmid:19595732 |
| Shah KB et al. | The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. | 2009 | Hypertension | pmid:19597033 |
| Hernández ML et al. | Expression analysis identifies FAD2-2 as the olive oleate desaturase gene mainly responsible for the linoleic acid content in virgin olive oil. | 2009 | J. Agric. Food Chem. | pmid:19601663 |
| Giroud S et al. | Dietary palmitate and linoleate oxidations, oxidative stress, and DNA damage differ according to season in mouse lemurs exposed to a chronic food deprivation. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19625694 |
| Poudel-Tandukar K et al. | Dietary intakes of alpha-linolenic and linoleic acids are inversely associated with serum C-reactive protein levels among Japanese men. | 2009 | Nutr Res | pmid:19628101 |
| Guillén MD and Uriarte PS | Contribution to further understanding of the evolution of sunflower oil submitted to frying temperature in a domestic fryer: study by 1H nuclear magnetic resonance. | 2009 | J. Agric. Food Chem. | pmid:19663427 |
| Lee OH et al. | Assessment of phenolics-enriched extract and fractions of olive leaves and their antioxidant activities. | 2009 | Bioresour. Technol. | pmid:19608415 |
| Fincham JR et al. | Fatty acid metabolism and deposition in subcutaneous adipose tissue of pasture- and feedlot-finished cattle. | 2009 | J. Anim. Sci. | pmid:19617512 |
| Tjonneland A et al. | Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case-control study within a European prospective cohort study. | 2009 | Gut | pmid:19628674 |
| de Groot RH et al. | Age dependence of plasma phospholipid fatty acid levels: potential role of linoleic acid in the age-associated increase in docosahexaenoic acid and eicosapentaenoic acid concentrations. | 2009 | Br. J. Nutr. | pmid:19402937 |
| Daly TJ et al. | Lack of genoprotective effect of phytosterols and conjugated linoleic acids on Caco-2 cells. | 2009 | Food Chem. Toxicol. | pmid:19406198 |
| Lux CA et al. | Hypersusceptibility of neutrophil granulocytes towards lethal action of free fatty acids contained in enzyme-modified atherogenic low density lipoprotein. | 2009 | Atherosclerosis | pmid:19423111 |
| Hamel FG | Preliminary report: inhibition of cellular proteasome activity by free fatty acids. | 2009 | Metab. Clin. Exp. | pmid:19423142 |
| Cheong SJ et al. | Superparamagnetic iron oxide nanoparticles-loaded chitosan-linoleic acid nanoparticles as an effective hepatocyte-targeted gene delivery system. | 2009 | Int J Pharm | pmid:19429277 |
| Fukasawa R et al. | Anti-oxidative effects of rooibos tea extract on autoxidation and thermal oxidation of lipids. | 2009 | J Oleo Sci | pmid:19430189 |
| Fang IM et al. | Comparative effects of fatty acids on proinflammatory gene cyclooxygenase 2 and inducible nitric oxide synthase expression in retinal pigment epithelial cells. | 2009 | Mol Nutr Food Res | pmid:19437483 |
| Grasso EJ and Calderón RO | Urinary bladder membrane permeability differentially induced by membrane lipid composition. | 2009 | Mol. Cell. Biochem. | pmid:19412731 |
| Yasuda M et al. | Linoleic acid metabolite suppresses skin inflammation and tumor promotion in mice: possible roles of programmed cell death 4 induction. | 2009 | Carcinogenesis | pmid:19414503 |
| Celia C et al. | Turbiscan lab expert analysis of the stability of ethosomes and ultradeformable liposomes containing a bilayer fluidizing agent. | 2009 | Colloids Surf B Biointerfaces | pmid:19376689 |
| Evans LM et al. | Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice. | 2009 | Clin. Exp. Metastasis | pmid:19267249 |
| Lata M et al. | Whole body protection against lethal ionizing radiation in mice by REC-2001: a semi-purified fraction of Podophyllum hexandrum. | 2009 | Phytomedicine | pmid:17574826 |
| Liang ZF et al. | [GC-MS analysis of the liposoluble components from fruits of Harrisonia perforata]. | 2009 | Zhong Yao Cai | pmid:20218293 |
| Mimoun M et al. | Increased tissue arachidonic acid and reduced linoleic acid in a mouse model of cystic fibrosis are reversed by supplemental glycerophospholipids enriched in docosahexaenoic acid. | 2009 | J. Nutr. | pmid:19828687 |
| Artwohl M et al. | Fatty acids induce apoptosis in human smooth muscle cells depending on chain length, saturation, and duration of exposure. | 2009 | Atherosclerosis | pmid:18597758 |
| Watanabe A et al. | In vitro free radical scavenging activity of platinum nanoparticles. | 2009 | Nanotechnology | pmid:19834242 |
| Hernández-Ledesma B et al. | Antioxidant and anti-inflammatory properties of cancer preventive peptide lunasin in RAW 264.7 macrophages. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19836349 |
| Shimomura H et al. | Steroids mediate resistance to the bactericidal effect of phosphatidylcholines against Helicobacter pylori. | 2009 | FEMS Microbiol. Lett. | pmid:19843309 |
| Chen Q et al. | Generation of fad2 transgenic mice that produce omega-6 fatty acids. | 2009 | Sci. China, C, Life Sci. | pmid:19937203 |
| Yang J et al. | Study of the inhibitory effect of fatty acids on the interaction between DNA and polymerase beta. | 2009 | Biochemistry Mosc. | pmid:19747104 |
| Detsi A et al. | Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. | 2009 | Bioorg. Med. Chem. | pmid:19853459 |
| Luo J et al. | Studies on the antioxidant activity and phenolic compounds of enzyme-assisted water extracts from Du-zhong (Eucommia ulmoides Oliv.) leaves. | 2009 | J Enzyme Inhib Med Chem | pmid:19912062 |
| Zhan ZJ et al. | Preparation and characterization of Cu,Zn-superoxide dismutase covalently modified by polyunsaturated fatty acids. | 2009 | Biochemistry Mosc. | pmid:19916943 |