Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Butovich IA et al. | The unusual action of (R,S)-2-hydroxy-2-trifluoromethyl-trans-n-octadec-4-enoic acid on 5-lipoxygenase from potato tubers. | 1991 | Eur. J. Biochem. | pmid:2065670 |
Rose DP and Connolly JM | Effects of fatty acids and eicosanoid synthesis inhibitors on the growth of two human prostate cancer cell lines. | 1991 | Prostate | pmid:2020620 |
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Bull AW et al. | Metabolism of oxidized linoleic acid: distribution of activity for the enzymatic oxidation of 13-hydroxyoctadecadienoic acid to 13-oxooctadecadienoic acid in rat tissues. | 1991 | Prostaglandins | pmid:2020745 |
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Venkatraman JT et al. | Influence of genotype on diet-induced changes in membrane phosphatidylcholine and phosphatidylethanolamine composition of splenocytes, liver nuclear envelope and liver mitochondria. | 1991 | Lipids | pmid:2046486 |
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Ramasamy S et al. | Linoleic acid-induced endothelial cell injury: role of membrane-bound enzyme activities and lipid oxidation. | 1991 | J. Biochem. Toxicol. | pmid:1831858 |
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Batres-Cerezo R et al. | Studies of women eating diets with different fatty acid composition. III. Fatty acids and prostaglandin synthesis by platelets and cultured human endothelial cells. | 1991 | J Am Coll Nutr | pmid:1894889 |
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Ikeda I et al. | Lymphatic absorption of structured glycerolipids containing medium-chain fatty acids and linoleic acid, and their effect on cholesterol absorption in rats. | 1991 | Lipids | pmid:1895884 |
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Huynh S et al. | Metabolic utilization of linoleate and alpha-linolenate in cultured Sertoli cells. | 1991 | Comp. Biochem. Physiol., B | pmid:1684926 |
de Tomás ME et al. | Metabolic transformation of intracraneally injected [1-14C]linoleic and [1-14C]alpha-linolenic acids in malnourished developing rats. | 1991 | Lipids | pmid:1687158 |
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Julu PO and Mutamba A | Comparison of short-term effects of insulin and essential fatty acids on the slowed nerve conduction of streptozotocin diabetes in rats. | 1991 | J. Neurol. Sci. | pmid:1663993 |
Benmansour N et al. | Effects of castration, dietary fat and adipose tissue sites on adipocyte plasma-membranes cyclic AMP phosphodiesterase activity in the pig. | 1991 | Int. J. Biochem. | pmid:1665423 |
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