Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zheng HF et al. | Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs. | 2005 | World J. Gastroenterol. | pmid:15655819 |
Chen BQ et al. | Effects of c9,t11-conjugated linoleic acid on adhesion of human gastric carcinoma cell line SGC-7901. | 2004 | World J. Gastroenterol. | pmid:15133841 |
Chen BQ et al. | Inhibition of conjugated linoleic acid on mouse forestomach neoplasia induced by benzo (a) pyrene and chemopreventive mechanisms. | 2003 | World J. Gastroenterol. | pmid:12508349 |
Ramsden CE et al. | All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts. | 2011 | World Rev Nutr Diet | pmid:21865817 |
Watkins BA et al. | Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. | 2001 | World Rev Nutr Diet | pmid:11545041 |
Holman RT | Highpoints in an affair with polyunsaturated fatty acids. | 1991 | World Rev Nutr Diet | pmid:2053355 |
Bibus DM and Stitt PA | Metabolism of alpha-linolenic acid from flaxseed in dogs. | 1998 | World Rev Nutr Diet | pmid:9648515 |
Okuyama H et al. | Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? | 2007 | World Rev Nutr Diet | pmid:17167283 |
Okuyama H et al. | Mechanisms by which dietary fats affect coronary heart disease mortality. | 2007 | World Rev Nutr Diet | pmid:17167284 |
Okuyama H et al. | Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. | 2007 | World Rev Nutr Diet | pmid:17167285 |